Hepatocellular adenoma history and symptoms: Difference between revisions
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{{CMG}}; {{AE}} {{ZAS}} | {{CMG}}; {{AE}} {{ZAS}} | ||
==Overview== | ==Overview== | ||
The small hepatocellular adenoma is generally asymptomatic. Typical clinical manifestations include spontaneous rupture or hemorrhage leading to acute abdominal pain with progression hypotension and even death. There is history of oral contraceptive use in women and long term anabolic steroids use in men. | The small [[hepatocellular adenoma]] is generally [[asymptomatic]]. Typical [[clinical]] manifestations include spontaneous [[rupture]] or [[hemorrhage]] leading to [[acute abdominal pain]] with progression [[hypotension]] and even death. There is history of [[Oral contraceptive|oral contraceptive use]] in women and long term [[anabolic]] [[steroids]] use in men. | ||
==Hepatocellular adenoma history and symptoms== | ==Hepatocellular adenoma history and symptoms== | ||
* The small hepatocellular adenoma is generally asymptomatic.<ref name="AgrawalAgarwal2015">{{cite journal|last1=Agrawal|first1=Shefali|last2=Agarwal|first2=Sheela|last3=Arnason|first3=Thomas|last4=Saini|first4=Sanjay|last5=Belghiti|first5=Jacques|title=Management of Hepatocellular Adenoma: Recent Advances|journal=Clinical Gastroenterology and Hepatology|volume=13|issue=7|year=2015|pages=1221–1230|issn=15423565|doi=10.1016/j.cgh.2014.05.023}}</ref><ref>{{Cite journal | * The small [[hepatocellular adenoma]] is generally [[asymptomatic]].<ref name="AgrawalAgarwal2015">{{cite journal|last1=Agrawal|first1=Shefali|last2=Agarwal|first2=Sheela|last3=Arnason|first3=Thomas|last4=Saini|first4=Sanjay|last5=Belghiti|first5=Jacques|title=Management of Hepatocellular Adenoma: Recent Advances|journal=Clinical Gastroenterology and Hepatology|volume=13|issue=7|year=2015|pages=1221–1230|issn=15423565|doi=10.1016/j.cgh.2014.05.023}}</ref><ref>{{Cite journal | ||
| author = [[Massimo Roncalli]], [[Amedeo Sciarra]] & [[Luca Di Tommaso]] | | author = [[Massimo Roncalli]], [[Amedeo Sciarra]] & [[Luca Di Tommaso]] | ||
| title = Benign hepatocellular nodules of healthy liver: focal nodular hyperplasia and hepatocellular adenoma | | title = Benign hepatocellular nodules of healthy liver: focal nodular hyperplasia and hepatocellular adenoma | ||
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| pmid = 21481415 | | pmid = 21481415 | ||
}}</ref> | }}</ref> | ||
* Abdominal pain is the most common symptom in other patients, that is usually related to tumoral hemorrhage. | * [[Abdominal pain]] is the most common [[symptom]] in other [[Patient|patients]], that is usually related to [[Tumor|tumoral]] [[hemorrhage]]. | ||
* Right upper quadrant abdominal fullness or discomfort is present in 40% of cases due to mass effect. | * [[Right upper quadrant]] [[Abdomen|abdominal]] fullness or [[discomfort]] is present in 40% of cases due to [[mass]] effect. | ||
* Typical clinical manifestation is spontaneous rupture or hemorrhage leading to acute abdominal pain with progression to hypotension and even death. | * Typical [[clinical]] manifestation is spontaneous [[rupture]] or [[hemorrhage]] leading to [[acute abdominal pain]] with progression to [[hypotension]] and even death. | ||
* There is history of oral contraceptive use in women and long term anabolic steroids use in men.<ref name="pmid18333188">{{cite journal| author=Barthelmes L, Tait IS| title=Liver cell adenoma and liver cell adenomatosis. | journal=HPB (Oxford) | year= 2005 | volume= 7 | issue= 3 | pages= 186-96 | pmid=18333188 | doi=10.1080/13651820510028954 | pmc=PMC2023950 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18333188 }} </ref><ref name=age>Introduction. Hindawi(2015). http://www.hindawi.com/journals/ijh/2013/374170. Accessed on November 2, 2015</ref> | * There is history of [[Oral contraceptive|oral contraceptive use]] in women and long term [[anabolic]] [[steroids]] use in men.<ref name="pmid18333188">{{cite journal| author=Barthelmes L, Tait IS| title=Liver cell adenoma and liver cell adenomatosis. | journal=HPB (Oxford) | year= 2005 | volume= 7 | issue= 3 | pages= 186-96 | pmid=18333188 | doi=10.1080/13651820510028954 | pmc=PMC2023950 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18333188 }} </ref><ref name="age">Introduction. Hindawi(2015). http://www.hindawi.com/journals/ijh/2013/374170. Accessed on November 2, 2015</ref> | ||
==References== | ==References== | ||
Revision as of 15:31, 15 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Zahir Ali Shaikh, MD[2]
Overview
The small hepatocellular adenoma is generally asymptomatic. Typical clinical manifestations include spontaneous rupture or hemorrhage leading to acute abdominal pain with progression hypotension and even death. There is history of oral contraceptive use in women and long term anabolic steroids use in men.
Hepatocellular adenoma history and symptoms
- The small hepatocellular adenoma is generally asymptomatic.[1][2][3]
- Abdominal pain is the most common symptom in other patients, that is usually related to tumoral hemorrhage.
- Right upper quadrant abdominal fullness or discomfort is present in 40% of cases due to mass effect.
- Typical clinical manifestation is spontaneous rupture or hemorrhage leading to acute abdominal pain with progression to hypotension and even death.
- There is history of oral contraceptive use in women and long term anabolic steroids use in men.[4][5]
References
- ↑ Agrawal, Shefali; Agarwal, Sheela; Arnason, Thomas; Saini, Sanjay; Belghiti, Jacques (2015). "Management of Hepatocellular Adenoma: Recent Advances". Clinical Gastroenterology and Hepatology. 13 (7): 1221–1230. doi:10.1016/j.cgh.2014.05.023. ISSN 1542-3565.
- ↑ Massimo Roncalli, Amedeo Sciarra & Luca Di Tommaso (2016). "Benign hepatocellular nodules of healthy liver: focal nodular hyperplasia and hepatocellular adenoma". Clinical and molecular hepatology. 22 (2): 199–211. doi:10.3350/cmh.2016.0101. PMID 27189732. Unknown parameter
|month=ignored (help) - ↑ David Q. Wang, Laurie M. Fiske, Caroline T. Carreras & David A. Weinstein (2011). "Natural history of hepatocellular adenoma formation in glycogen storage disease type I". The Journal of pediatrics. 159 (3): 442–446. doi:10.1016/j.jpeds.2011.02.031. PMID 21481415. Unknown parameter
|month=ignored (help) - ↑ Barthelmes L, Tait IS (2005). "Liver cell adenoma and liver cell adenomatosis". HPB (Oxford). 7 (3): 186–96. doi:10.1080/13651820510028954. PMC 2023950. PMID 18333188.
- ↑ Introduction. Hindawi(2015). http://www.hindawi.com/journals/ijh/2013/374170. Accessed on November 2, 2015