Breast lumps differential diagnosis: Difference between revisions

Jump to navigation Jump to search
← Older editNewer edit →
VisualWikitext
No edit summary
No edit summary
Line 8: Line 8:
Differential diagnosis of [[breast lumps]] include: <ref name="pmid15691804">{{cite journal| author=Cheung KL, Lam TP| title=Approach to a lump in the breast: a regional perspective. | journal=Asian J Surg | year= 2005 | volume= 28 | issue= 1 | pages= 65-70 | pmid=15691804 | doi=10.1016/S1015-9584(09)60264-5 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15691804  }} </ref><ref name="pmid11560983">{{cite journal| author=Collyar DE| title=Breast cancer: a global perspective. | journal=J Clin Oncol | year= 2001 | volume= 19 | issue= 18 Suppl | pages= 101S-105S | pmid=11560983 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11560983  }} </ref><ref name="pmid3307689">{{cite journal| author=Lang AP, Luchsinger IS, Rawling EG| title=Filariasis of the breast. | journal=Arch Pathol Lab Med | year= 1987 | volume= 111 | issue= 8 | pages= 757-9 | pmid=3307689 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3307689  }} </ref><ref name="pmid8629415">{{cite journal| author=Varghese R, Raghuveer CV, Pai MR, Bansal R| title=Microfilariae in cytologic smears: a report of six cases. | journal=Acta Cytol | year= 1996 | volume= 40 | issue= 2 | pages= 299-301 | pmid=8629415 | doi=10.1159/000333755 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8629415  }} </ref><ref>Alagaratnam, T.T. & Wong, J. World J. Surg. (1989) 13: 743. https://doi.org/10.1007/BF01658425</ref><ref name="pmid2623884">{{cite journal| author=Shukla HS, Kumar S| title=Benign breast disorders in nonwestern populations: Part II--Benign breast disorders in India. | journal=World J Surg | year= 1989 | volume= 13 | issue= 6 | pages= 746-9 | pmid=2623884 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2623884  }} </ref><ref name="pmid11574178">{{cite journal| author=Leung TN, Haines CJ, Chung TK| title=Five-year compliance with hormone replacement therapy in postmenopausal Chinese women in Hong Kong. | journal=Maturitas | year= 2001 | volume= 39 | issue= 3 | pages= 195-201 | pmid=11574178 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11574178  }} </ref>
Differential diagnosis of [[breast lumps]] include: <ref name="pmid15691804">{{cite journal| author=Cheung KL, Lam TP| title=Approach to a lump in the breast: a regional perspective. | journal=Asian J Surg | year= 2005 | volume= 28 | issue= 1 | pages= 65-70 | pmid=15691804 | doi=10.1016/S1015-9584(09)60264-5 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15691804  }} </ref><ref name="pmid11560983">{{cite journal| author=Collyar DE| title=Breast cancer: a global perspective. | journal=J Clin Oncol | year= 2001 | volume= 19 | issue= 18 Suppl | pages= 101S-105S | pmid=11560983 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11560983  }} </ref><ref name="pmid3307689">{{cite journal| author=Lang AP, Luchsinger IS, Rawling EG| title=Filariasis of the breast. | journal=Arch Pathol Lab Med | year= 1987 | volume= 111 | issue= 8 | pages= 757-9 | pmid=3307689 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3307689  }} </ref><ref name="pmid8629415">{{cite journal| author=Varghese R, Raghuveer CV, Pai MR, Bansal R| title=Microfilariae in cytologic smears: a report of six cases. | journal=Acta Cytol | year= 1996 | volume= 40 | issue= 2 | pages= 299-301 | pmid=8629415 | doi=10.1159/000333755 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8629415  }} </ref><ref>Alagaratnam, T.T. & Wong, J. World J. Surg. (1989) 13: 743. https://doi.org/10.1007/BF01658425</ref><ref name="pmid2623884">{{cite journal| author=Shukla HS, Kumar S| title=Benign breast disorders in nonwestern populations: Part II--Benign breast disorders in India. | journal=World J Surg | year= 1989 | volume= 13 | issue= 6 | pages= 746-9 | pmid=2623884 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2623884  }} </ref><ref name="pmid11574178">{{cite journal| author=Leung TN, Haines CJ, Chung TK| title=Five-year compliance with hormone replacement therapy in postmenopausal Chinese women in Hong Kong. | journal=Maturitas | year= 2001 | volume= 39 | issue= 3 | pages= 195-201 | pmid=11574178 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11574178  }} </ref>
{|
{|
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases
! style="background: #4479BA; color: #FFFFFF; text-align: center;" rowspan="3" |Diseases
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Etiology
! style="background: #4479BA; color: #FFFFFF; text-align: center;" rowspan="3" |Etiology
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Benign
! style="background: #4479BA; color: #FFFFFF; text-align: center;" rowspan="3" |Benign
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Malignant
! style="background: #4479BA; color: #FFFFFF; text-align: center;" rowspan="3" |Malignant
! colspan="9" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Clinical manifestation
! style="background: #4479BA; color: #FFFFFF; text-align: center;" colspan="9" |Clinical manifestation
! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Paraclinical findings
! style="background: #4479BA; color: #FFFFFF; text-align: center;" colspan="3" |Paraclinical findings
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard diagnosis
! style="background: #4479BA; color: #FFFFFF; text-align: center;" rowspan="3" |Gold standard diagnosis
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
! style="background: #4479BA; color: #FFFFFF; text-align: center;" rowspan="3" |Associated findings
|-
|-
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Demography
! style="background: #4479BA; color: #FFFFFF; text-align: center;" rowspan="2" |Demography
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |History
! style="background: #4479BA; color: #FFFFFF; text-align: center;" rowspan="2" |History
! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptoms
! style="background: #4479BA; color: #FFFFFF; text-align: center;" colspan="3" |Symptoms
! colspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Signs
! style="background: #4479BA; color: #FFFFFF; text-align: center;" colspan="4" |Signs
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab findings
! style="background: #4479BA; color: #FFFFFF; text-align: center;" rowspan="2" |Lab findings
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Histopathology
! style="background: #4479BA; color: #FFFFFF; text-align: center;" rowspan="2" |Histopathology
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging
! style="background: #4479BA; color: #FFFFFF; text-align: center;" rowspan="2" |Imaging
|-
|-
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Mass
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Mass
Line 33: Line 33:
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Others
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Others
|-
|-
! style="background:#DCDCDC;" align="center" |[[Fibroadenoma]]<ref name="PintoAguiar2014">{{cite journal|last1=Pinto|first1=Joana|last2=Aguiar|first2=Ana Teresa|last3=Duarte|first3=Hálio|last4=Vilaverde|first4=Filipa|last5=Rodrigues|first5=Ângelo|last6=Krug|first6=José Luís|title=Simple and Complex Fibroadenomas|journal=Journal of Ultrasound in Medicine|volume=33|issue=3|year=2014|pages=415–419|issn=02784297|doi=10.7863/ultra.33.3.415}}</ref>
! align="center" style="background:#DCDCDC;" |[[Fibroadenoma]]<ref name="PintoAguiar2014">{{cite journal|last1=Pinto|first1=Joana|last2=Aguiar|first2=Ana Teresa|last3=Duarte|first3=Hálio|last4=Vilaverde|first4=Filipa|last5=Rodrigues|first5=Ângelo|last6=Krug|first6=José Luís|title=Simple and Complex Fibroadenomas|journal=Journal of Ultrasound in Medicine|volume=33|issue=3|year=2014|pages=415–419|issn=02784297|doi=10.7863/ultra.33.3.415}}</ref>
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
* Unknown
* Unknown
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
* Very slight increased risk of breast cancer in complex fibroadenoma
* Very slight increased risk of breast cancer in complex fibroadenoma
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
* Most common benign tumor, women aged 20-30 years
* Most common benign tumor, women aged 20-30 years
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
* Increased in size during pregnancy or with estrogen therapy, and regress after menopause
* Increased in size during pregnancy or with estrogen therapy, and regress after menopause
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |±
| align="center" style="background:#F5F5F5;" |±
| style="background:#F5F5F5;" align="center" |–
| align="center" style="background:#F5F5F5;" |–
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
* Solitary,
* Solitary,


* well-defined
* well-defined
* mobile mass
* mobile mass
| style="background:#F5F5F5;" align="center" |–
| align="center" style="background:#F5F5F5;" |–
| style="background:#F5F5F5;" align="center" |–
| align="center" style="background:#F5F5F5;" |–
| style="background:#F5F5F5;" align="center" |NA
| align="center" style="background:#F5F5F5;" |NA
| style="background:#F5F5F5;" align="center" |Nl
| align="center" style="background:#F5F5F5;" |Nl
| style="background:#F5F5F5;" align="center" |Proliferative breast lesion without atypia
| align="center" style="background:#F5F5F5;" |Proliferative breast lesion without atypia
| style="background:#F5F5F5;" align="center" |Well-defined, solid mass
| align="center" style="background:#F5F5F5;" |Well-defined, solid mass
| style="background:#F5F5F5;" align="center" | Mammography or ultrasound + biopsy
| align="center" style="background:#F5F5F5;" | Mammography or ultrasound + biopsy
| style="background:#F5F5F5;" align="center" |NA
| align="center" style="background:#F5F5F5;" |NA
|-
|-
! style="background:#DCDCDC;" align="center" |[[Breast]] [[cyst]]<ref name="pmid16900392">{{cite journal| author=Courtillot C, Plu-Bureau G, Binart N, Balleyguier C, Sigal-Zafrani B, Goffin V et al.| title=Benign breast diseases. | journal=J Mammary Gland Biol Neoplasia | year= 2005 | volume= 10 | issue= 4 | pages= 325-35 | pmid=16900392 | doi=10.1007/s10911-006-9006-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16900392  }}</ref>
! align="center" style="background:#DCDCDC;" |[[Breast]] [[cyst]]<ref name="pmid16900392">{{cite journal| author=Courtillot C, Plu-Bureau G, Binart N, Balleyguier C, Sigal-Zafrani B, Goffin V et al.| title=Benign breast diseases. | journal=J Mammary Gland Biol Neoplasia | year= 2005 | volume= 10 | issue= 4 | pages= 325-35 | pmid=16900392 | doi=10.1007/s10911-006-9006-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16900392  }}</ref>
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
* Hormonal fluctuation
* Hormonal fluctuation
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
* No increased risk of malignancy for simple cyst
* No increased risk of malignancy for simple cyst
* <1% for complicated cyst
* <1% for complicated cyst
* <1% to 23% for complex cyst
* <1% to 23% for complex cyst
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
* Hormonal replacement therapy (HRT)
* Hormonal replacement therapy (HRT)
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
* Found in premenopausal, perimenopausal, and postmenopausal women
* Found in premenopausal, perimenopausal, and postmenopausal women
* Mostly seen among HRT users
* Mostly seen among HRT users
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |±
| align="center" style="background:#F5F5F5;" |±
| style="background:#F5F5F5;" align="center" |–
| align="center" style="background:#F5F5F5;" |–
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
* Solitary
* Solitary
* Cluster of small masses or an ill-defined mass
* Cluster of small masses or an ill-defined mass
* Smooth, firm, and frequently tender
* Smooth, firm, and frequently tender
| style="background:#F5F5F5;" align="center" |–
| align="center" style="background:#F5F5F5;" |–
| style="background:#F5F5F5;" align="center" |–
| align="center" style="background:#F5F5F5;" |–
| style="background:#F5F5F5;" align="center" |NA
| align="center" style="background:#F5F5F5;" |NA
| style="background:#F5F5F5;" align="center" |Nl
| align="center" style="background:#F5F5F5;" |Nl
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
* Nonproliferative breast lesions
* Nonproliferative breast lesions
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
* simple cyst: Well circumscribed,posterior acoustic enhancement without internal echoes  
* simple cyst: Well circumscribed,posterior acoustic enhancement without internal echoes  
* Complicated cyst: Homogenous low-level internal echoes due to without solid components
* Complicated cyst: Homogenous low-level internal echoes due to without solid components
* Complex cyst: thick walls greater than 0.5 mm with solid component
* Complex cyst: thick walls greater than 0.5 mm with solid component
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
* Ultrasound
* Ultrasound
* Fine needle aspiration (FNA) for confirmation
* Fine needle aspiration (FNA) for confirmation
|NA
|NA
|-
|-
! style="background:#DCDCDC;" align="center" |Fibrocystic change
! align="center" style="background:#DCDCDC;" |Fibrocystic change
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Galactocele
! align="center" style="background:#DCDCDC;" |Galactocele
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |Milk duct obstruction
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |No increased risk of malignancy
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
* Milk retention cysts
| style="background:#F5F5F5;" align="center" |
* Fluid collection
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
* pregnant women
| style="background:#F5F5F5;" align="center" |
* During breast-feeding
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |+
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |±
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |±
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
* Soft masses
| style="background:#F5F5F5;" align="center" |
* Cystic masses
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |–
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |NA
| align="center" style="background:#F5F5F5;" |Nl
| align="center" style="background:#F5F5F5;" |Nonproliferative breast lesions
| align="center" style="background:#F5F5F5;" |
* Mammography: Intermediate mass in absence of classic fat-fluid level
* Ultrasound: Complex mass
| align="center" style="background:#F5F5F5;" |
* Ultrasound
* Mammography
| align="center" style="background:#F5F5F5;" | NA
|-
|-
! style="background:#DCDCDC;" align="center" |Cysts of montgomery
! align="center" style="background:#DCDCDC;" |Cysts of montgomery
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |[[Hemangioma]]
! align="center" style="background:#DCDCDC;" |[[Hemangioma]]
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Breast abscess
! align="center" style="background:#DCDCDC;" |Breast abscess
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Mastitis
! align="center" style="background:#DCDCDC;" |Mastitis
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
* Inflammation
* Inflammation
* Infection
* Infection
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases
Line 230: Line 240:
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
|-
|-
! style="background:#DCDCDC;" align="center" |Breast carcinoma
! align="center" style="background:#DCDCDC;" |Breast carcinoma
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |Positive [[family history]]
| align="center" style="background:#F5F5F5;" |Positive [[family history]]
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Ductal carcinoma in situ
! align="center" style="background:#DCDCDC;" |Ductal carcinoma in situ
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Microinvasive breast cancer
! align="center" style="background:#DCDCDC;" |Microinvasive breast cancer
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Breast sarcoma
! align="center" style="background:#DCDCDC;" |Breast sarcoma
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Paget disease
! align="center" style="background:#DCDCDC;" |Paget disease
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |[[Phyllodes tumor]]
! align="center" style="background:#DCDCDC;" |[[Phyllodes tumor]]
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Lymphoma
! align="center" style="background:#DCDCDC;" |Lymphoma
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Metastasis
! align="center" style="background:#DCDCDC;" |Metastasis
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Duct ectasia
! align="center" style="background:#DCDCDC;" |Duct ectasia
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Intraductal [[papilloma]]
! align="center" style="background:#DCDCDC;" |Intraductal [[papilloma]]
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Lipoma
! align="center" style="background:#DCDCDC;" |Lipoma
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases
Line 458: Line 468:
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
|-
|-
! style="background:#DCDCDC;" align="center" |[[Neurofibroma]]
! align="center" style="background:#DCDCDC;" |[[Neurofibroma]]
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Pregnancy
! align="center" style="background:#DCDCDC;" |Pregnancy
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Gynecomastia
! align="center" style="background:#DCDCDC;" |Gynecomastia
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Premenstrual syndrome
! align="center" style="background:#DCDCDC;" |Premenstrual syndrome
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Breast trauma
! align="center" style="background:#DCDCDC;" |Breast trauma
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Fat necrosis
! align="center" style="background:#DCDCDC;" |Fat necrosis
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background:#DCDCDC;" align="center" |Drugs
! align="center" style="background:#DCDCDC;" |Drugs
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" | +
| align="center" style="background:#F5F5F5;" | +
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |
| align="center" style="background:#F5F5F5;" |
| style="background:#F5F5F5;" align="center" |  
| align="center" style="background:#F5F5F5;" |  
|-
|-
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases

Revision as of 15:16, 16 January 2019

Breast lumps Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Breast lumps from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Breast lumps differential diagnosis On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Breast lumps differential diagnosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Breast lumps differential diagnosis

on Breast lumps differential diagnosis

Breast lumps differential diagnosis in the news

Blogs on Breast lumps differential diagnosis

Directions to Hospitals Treating Breast lumps

Risk calculators and risk factors for Breast lumps differential diagnosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]

Overview

Breast lumps must be differentiated from other diseases such as malignancy, cysts, inflammation and non-inflammatory solid lumps. Breast symptoms such as nipple discharge and mastalgia require assessment as well.

Differentiating Breast lumps from other Diseases

Differential diagnosis of breast lumps include: [1][2][3][4][5][6][7]

Diseases Etiology Benign Malignant Clinical manifestation Paraclinical findings Gold standard diagnosis Associated findings
Demography History Symptoms Signs Lab findings Histopathology Imaging
Mass Mastalgia Nipple discharge Breast exam Skin changes LAP Others
Fibroadenoma[8]
  • Unknown
 +
  • Very slight increased risk of breast cancer in complex fibroadenoma
  • Most common benign tumor, women aged 20-30 years
  • Increased in size during pregnancy or with estrogen therapy, and regress after menopause
 + ± –
  • Solitary,
  • well-defined
  • mobile mass
 – – NA Nl Proliferative breast lesion without atypia Well-defined, solid mass Mammography or ultrasound + biopsy NA
Breast cyst[9]
  • Hormonal fluctuation
 +
  • No increased risk of malignancy for simple cyst
  • <1% for complicated cyst
  • <1% to 23% for complex cyst
  • Hormonal replacement therapy (HRT)
  • Found in premenopausal, perimenopausal, and postmenopausal women
  • Mostly seen among HRT users
 + ± –
  • Solitary
  • Cluster of small masses or an ill-defined mass
  • Smooth, firm, and frequently tender
 – – NA Nl
  • Nonproliferative breast lesions
  • simple cyst: Well circumscribed,posterior acoustic enhancement without internal echoes
  • Complicated cyst: Homogenous low-level internal echoes due to without solid components
  • Complex cyst: thick walls greater than 0.5 mm with solid component
  • Ultrasound
  • Fine needle aspiration (FNA) for confirmation
 NA
Fibrocystic change +
Galactocele Milk duct obstruction + No increased risk of malignancy
  • Milk retention cysts
  • Fluid collection
  • pregnant women
  • During breast-feeding
 + ± ±
  • Soft masses
  • Cystic masses
 – – NA Nl Nonproliferative breast lesions
  • Mammography: Intermediate mass in absence of classic fat-fluid level
  • Ultrasound: Complex mass
  • Ultrasound
  • Mammography
 NA
Cysts of montgomery +
Hemangioma +
Breast abscess +
Mastitis
  • Inflammation
  • Infection
 +
Diseases Etiology Benign Malignant Demography History Mass Pain Nipple discharge Breast exam Skin changes LAP Others Lab findings Histopathology Imaging Gold standard diagnosis Associated findings
Breast carcinoma + Positive family history
Ductal carcinoma in situ +
Microinvasive breast cancer +
Breast sarcoma +
Paget disease +
Phyllodes tumor +
Lymphoma +
Metastasis +
Duct ectasia +
Intraductal papilloma +
Lipoma +
Diseases Etiology Benign Malignant Demography History Mass Pain Nipple discharge Breast exam Skin changes LAP Others Lab findings Histopathology Imaging Gold standard diagnosis Associated findings
Neurofibroma +
Pregnancy +
Gynecomastia +
Premenstrual syndrome +
Breast trauma +
Fat necrosis +
Drugs +
Diseases Etiology Benign Malignant Demography History Mass Pain Nipple discharge Breast exam Skin changes LAP Others Lab findings Histopathology Imaging Gold standard diagnosis Associated findings

NA

References

  1. ↑ Cheung KL, Lam TP (2005). "Approach to a lump in the breast: a regional perspective". Asian J Surg. 28 (1): 65–70. doi:10.1016/S1015-9584(09)60264-5. PMID 15691804.
  2. ↑ Collyar DE (2001). "Breast cancer: a global perspective". J Clin Oncol. 19 (18 Suppl): 101S–105S. PMID 11560983.
  3. ↑ Lang AP, Luchsinger IS, Rawling EG (1987). "Filariasis of the breast". Arch Pathol Lab Med. 111 (8): 757–9. PMID 3307689.
  4. ↑ Varghese R, Raghuveer CV, Pai MR, Bansal R (1996). "Microfilariae in cytologic smears: a report of six cases". Acta Cytol. 40 (2): 299–301. doi:10.1159/000333755. PMID 8629415.
  5. ↑ Alagaratnam, T.T. & Wong, J. World J. Surg. (1989) 13: 743. https://doi.org/10.1007/BF01658425
  6. ↑ Shukla HS, Kumar S (1989). "Benign breast disorders in nonwestern populations: Part II--Benign breast disorders in India". World J Surg. 13 (6): 746–9. PMID 2623884.
  7. ↑ Leung TN, Haines CJ, Chung TK (2001). "Five-year compliance with hormone replacement therapy in postmenopausal Chinese women in Hong Kong". Maturitas. 39 (3): 195–201. PMID 11574178.
  8. ↑ Pinto, Joana; Aguiar, Ana Teresa; Duarte, Hálio; Vilaverde, Filipa; Rodrigues, Ângelo; Krug, José Luís (2014). "Simple and Complex Fibroadenomas". Journal of Ultrasound in Medicine. 33 (3): 415–419. doi:10.7863/ultra.33.3.415. ISSN 0278-4297.
  9. ↑ Courtillot C, Plu-Bureau G, Binart N, Balleyguier C, Sigal-Zafrani B, Goffin V; et al. (2005). "Benign breast diseases". J Mammary Gland Biol Neoplasia. 10 (4): 325–35. doi:10.1007/s10911-006-9006-4. PMID 16900392.


Template:WikiDoc Sources

Retrieved from "https://www.wikidoc.org/index.php?title=Breast_lumps_differential_diagnosis&oldid=1536441"