Appendix cancer natural history, complications and prognosis: Difference between revisions
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*[Subtype of disease/malignancy] is associated with the most favorable prognosis. | *[Subtype of disease/malignancy] is associated with the most favorable prognosis. | ||
*The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis. | *The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis. | ||
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*'''The 5-year survival''' | *'''The 5-year survival''' | ||
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**Distant metastasis 51% | **Distant metastasis 51% | ||
* '''Poor prognostic factors for adenocarcinoma''' are as follows: | * '''Poor prognostic factors''' for '''appendiceal adenocarcinoma''' are as follows: | ||
** Advanced stage | ** Advanced stage | ||
**High grade | **High grade | ||
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** Spread of the tumor beyond the left lower quadrant | ** Spread of the tumor beyond the left lower quadrant | ||
** Presence of malignant cells outside of the visceral peritoneum of the appendix | ** Presence of malignant cells outside of the visceral peritoneum of the appendix | ||
** Poor prognostic factors '''''in the presence of pseudomyxoma peritonei''''' | |||
** abdominal distension | |||
** weight loss | |||
** high histological grade | |||
** and morphological evidence of invasion of underlying structures | |||
==References== | ==References== | ||
Revision as of 16:41, 16 January 2019
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Appendix cancer Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]
Overview
If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
OR
Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
OR
Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
Natural History, Complications, and Prognosis
Natural History
- The symptoms of (disease name) usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
- The symptoms of (disease name) typically develop ___ years after exposure to ___.
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Complications
- Common complications of [disease name] include:
- [Complication 1]
- [Complication 2]
- [Complication 3]
Prognosis
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [--]%.
- Depending on the extent of the [tumor/disease progression] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.
| Template:Five year survival | ||
|---|---|---|
| Carcinoid tumors | ||
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| Adenocarcinoma | ||
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- The 5-year survival
- Appendiceal carcinoid tumors
- 94% localized disease
- 85% regional disease
- 34% distant metastases
- goblet cell 12.5%
- Tubular tumors are benign clinically
- Adenocarcinoma
- localized 95%
- Distant metastasis 0%
- Mucinous
- localized 80%
- Distant metastasis 51%
- Poor prognostic factors for appendiceal adenocarcinoma are as follows:
- Advanced stage
- High grade
- Nonmucinous histology
- Spread of the tumor beyond the left lower quadrant
- Presence of malignant cells outside of the visceral peritoneum of the appendix
- Poor prognostic factors in the presence of pseudomyxoma peritonei
- abdominal distension
- weight loss
- high histological grade
- and morphological evidence of invasion of underlying structures