Appendix cancer risk factors: Difference between revisions
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==Risk Factors== | ==Risk Factors== | ||
===Common Risk Factors=== | ===Common Risk Factors=== | ||
*Common risk factors in the development of | *Common risk factors in the development of appendix cancers include: | ||
**Smoking | **Smoking | ||
**[[Multiple endocrine neoplasia type 1|Multiple endocrine neoplasia type 1 (MEN1) syndrome]] | **[[Multiple endocrine neoplasia type 1|Multiple endocrine neoplasia type 1 (MEN1) syndrome]] | ||
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***Adenocarcinoma peak age 60s decade while carcinoid tumors are prevalent in 40s. <ref name="pmid9024720">{{cite journal| author=Modlin IM, Sandor A| title=An analysis of 8305 cases of carcinoid tumors. | journal=Cancer | year= 1997 | volume= 79 | issue= 4 | pages= 813-29 | pmid=9024720 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9024720 }} </ref><ref name="pmid7795991">{{cite journal| author=Deans GT, Spence RA| title=Neoplastic lesions of the appendix. | journal=Br J Surg | year= 1995 | volume= 82 | issue= 3 | pages= 299-306 | pmid=7795991 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7795991 }} </ref> | ***Adenocarcinoma peak age 60s decade while carcinoid tumors are prevalent in 40s. <ref name="pmid9024720">{{cite journal| author=Modlin IM, Sandor A| title=An analysis of 8305 cases of carcinoid tumors. | journal=Cancer | year= 1997 | volume= 79 | issue= 4 | pages= 813-29 | pmid=9024720 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9024720 }} </ref><ref name="pmid7795991">{{cite journal| author=Deans GT, Spence RA| title=Neoplastic lesions of the appendix. | journal=Br J Surg | year= 1995 | volume= 82 | issue= 3 | pages= 299-306 | pmid=7795991 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7795991 }} </ref> | ||
===Less Common Risk Factors=== | ===Less Common Risk Factors=== | ||
*Less common risk factors in the development of | *Less common risk factors in the development of appendix cancers include: | ||
**Chronic inflammatory disease specially [[ulcerative colitis]].<ref name="pmid7942699">{{cite journal| author=Odze RD, Medline P, Cohen Z| title=Adenocarcinoma arising in an appendix involved with chronic ulcerative colitis. | journal=Am J Gastroenterol | year= 1994 | volume= 89 | issue= 10 | pages= 1905-7 | pmid=7942699 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7942699 }} </ref> | **Chronic inflammatory disease specially [[ulcerative colitis]].<ref name="pmid7942699">{{cite journal| author=Odze RD, Medline P, Cohen Z| title=Adenocarcinoma arising in an appendix involved with chronic ulcerative colitis. | journal=Am J Gastroenterol | year= 1994 | volume= 89 | issue= 10 | pages= 1905-7 | pmid=7942699 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7942699 }} </ref> | ||
**'''Sex'''<ref name="pmid7795991">{{cite journal| author=Deans GT, Spence RA| title=Neoplastic lesions of the appendix. | journal=Br J Surg | year= 1995 | volume= 82 | issue= 3 | pages= 299-306 | pmid=7795991 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7795991 }} </ref> | **'''Sex'''<ref name="pmid7795991">{{cite journal| author=Deans GT, Spence RA| title=Neoplastic lesions of the appendix. | journal=Br J Surg | year= 1995 | volume= 82 | issue= 3 | pages= 299-306 | pmid=7795991 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7795991 }} </ref> | ||
Revision as of 20:10, 16 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]
Overview
Alike other malignancies, common risk factors in the development of appendix cancer are a combination of environmental and genetic factors.
Common risk factors in the development of appendix cancer include age, sex, smoking, MEN1 Syndrome, and medical conditions which affect gastric acid secretion like atrophic gastritis, pernicious anemia and Zollinger-Ellison syndrome.
Risk Factors
Common Risk Factors
- Common risk factors in the development of appendix cancers include:
- Smoking
- Multiple endocrine neoplasia type 1 (MEN1) syndrome
- Any condition that influence acid production of stomach like atrophic gastritis, pernicious anemia and Zollinger-Ellison syndrome
- Age
Less Common Risk Factors
- Less common risk factors in the development of appendix cancers include:
- Chronic inflammatory disease specially ulcerative colitis.[3]
- Sex[2]
- There is a male dominant pattern of prevalence in adenocarcinoma of appendix.
- Although it is still controversial, most of the published studies demonstrated that females are more commonly affected by appendiceal carcinoids than men. [4]
References
- ↑ Modlin IM, Sandor A (1997). "An analysis of 8305 cases of carcinoid tumors". Cancer. 79 (4): 813–29. PMID 9024720.
- ↑ 2.0 2.1 Deans GT, Spence RA (1995). "Neoplastic lesions of the appendix". Br J Surg. 82 (3): 299–306. PMID 7795991.
- ↑ Odze RD, Medline P, Cohen Z (1994). "Adenocarcinoma arising in an appendix involved with chronic ulcerative colitis". Am J Gastroenterol. 89 (10): 1905–7. PMID 7942699.
- ↑ Syracuse DC, Perzin KH, Price JB, Wiedel PD, Mesa-Tejada R (1979). "Carcinoid tumors of the appendix. Mesoappendiceal extension and nodal metastases". Ann Surg. 190 (1): 58–63. PMC 1344458. PMID 464679.