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! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Focal neurologic deficit
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Focal neurologic deficit
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |EPO
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |EPO
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Prolactin
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Endocrine abnormalities
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |CT scan
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |CT scan
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |MRI
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |MRI
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* Pseudopalisading appearance
* Pseudopalisading appearance


* GFAP+
* GFAP +


* Necrosis+
* Necrosis +


* Hemorrhage+
* Hemorrhage +


* Vascular prolifration+
* Vascular prolifration +
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* Oligodendrocyte origin
* Oligodendrocyte origin


* Calcification+
* Calcification +


* Fried egg cell appearance
* Fried egg cell appearance
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* Glial cell origin
* Solid and cystic component
* GFAP +
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* Neuroectoderm origin
* Homer wright rosettes
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* Ependymal cell origin
* Perivascular pseudorosette
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* Ectodermal origin (Rathkes pouch)
* Calcification +
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| style="background: #F5F5F5; padding: 5px;" |+
B-hCG rise leads to precocious puberty in males
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* Similar to testicular seminoma
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Revision as of 15:34, 17 January 2019

Astrocytoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Astrocytoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.

Overview

Differentiating astrocytoma from other Diseases

Diseases Clinical manifestations Para-clinical findings Gold standard Additional findings
Symptoms Physical examination
Lab Findings Imaging Histopathology
Headache Seizure Visual disturbance Hearing loss Constitutional Extraocular movement disorder Hydrocephalus Focal neurologic deficit EPO Endocrine abnormalities CT scan MRI
Adult primary brain tumors Glioblastoma multiform + − +
  • Astrocyte origin
  • Pleomorphic cell
  • Pseudopalisading appearance
  • GFAP +
  • Necrosis +
  • Hemorrhage +
  • Vascular prolifration +
Oligodendroglioma + − +
  • Oligodendrocyte origin
  • Calcification +
  • Fried egg cell appearance
Meningioma + − +
  • Arachnoid origin
  • Psammoma bodies
  • Whorled spindle cell pattern
Hemangioblastoma + − + +
  • Blood vessel origin
  • Capillaries with thin walls
Pitutary adenoma + + Bitemporal hemianopia − − +/−
  • Endocrine cell hyperplasia
Schwannoma + + −
  • Schwann cell origin
  • S100+
primary CNS lymphoma + −
  • B cell origin
  • Similar to non hodgkin lymphoma (diffuse large B cell)
Childhood primary brain tumors Pilocytic astrocytoma + −
  • Glial cell origin
  • Solid and cystic component
  • GFAP +
Medulloblastoma + +
  • Neuroectoderm origin
  • Homer wright rosettes
Ependymoma + +
  • Ependymal cell origin
  • Perivascular pseudorosette
Craniopharyngioma + + Bitemporal hemianopia −
  • Ectodermal origin (Rathkes pouch)
  • Calcification +
Pinealoma + + vertical gaze palsy − +

B-hCG rise leads to precocious puberty in males

  • Similar to testicular seminoma
Vascular AV malformation + −
Brain aneurysm + −
Infectious Bacterial brain abscess + + −
Tuberculosis + + −
Toxoplasmosis + −
Hydatid cyst + −
Fungal + −
Other Brain metastasis + −

References

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