Astrocytoma differential diagnosis: Difference between revisions

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! colspan="2" rowspan="4" |Diseases
! colspan="2" rowspan="4" |Diseases
| colspan="8" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Clinical manifestations'''
| colspan="8" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Clinical manifestations'''
! colspan="5" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Para-clinical findings
! colspan="4" rowspan="2" |Para-clinical findings
| colspan="1" rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Gold standard'''
| colspan="1" rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Gold standard'''
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Additional findings
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Additional findings
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! colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical examination
! colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical examination
|-
|-
! colspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab Findings
!Lab Findings
! colspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging
! colspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Histopathology
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Histopathology
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! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hydrocephalus
! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Hydrocephalus
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Focal neurologic deficit
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Focal neurologic deficit
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |EPO
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Endocrine abnormalities
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Endocrine abnormalities
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |CT scan
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |CT scan
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B-hCG rise leads to precocious puberty in males
B-hCG rise leads to precocious puberty in males
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Revision as of 15:35, 17 January 2019

Astrocytoma Microchapters

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Patient Information

Overview

Historical Perspective

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Differentiating Astrocytoma from other Diseases

Epidemiology and Demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.

Overview

Differentiating astrocytoma from other Diseases

Diseases Clinical manifestations Para-clinical findings Gold standard Additional findings
Symptoms Physical examination
Lab Findings Imaging Histopathology
Headache Seizure Visual disturbance Hearing loss Constitutional Extraocular movement disorder Hydrocephalus Focal neurologic deficit Endocrine abnormalities CT scan MRI
Adult primary brain tumors Glioblastoma multiform + − +
  • Astrocyte origin
  • Pleomorphic cell
  • Pseudopalisading appearance
  • GFAP +
  • Necrosis +
  • Hemorrhage +
  • Vascular prolifration +
Oligodendroglioma + − +
  • Oligodendrocyte origin
  • Calcification +
  • Fried egg cell appearance
Meningioma + − +
  • Arachnoid origin
  • Psammoma bodies
  • Whorled spindle cell pattern
Hemangioblastoma + − +
  • Blood vessel origin
  • Capillaries with thin walls
Pitutary adenoma + + Bitemporal hemianopia − − +/−
  • Endocrine cell hyperplasia
Schwannoma + + −
  • Schwann cell origin
  • S100+
primary CNS lymphoma + −
  • B cell origin
  • Similar to non hodgkin lymphoma (diffuse large B cell)
Childhood primary brain tumors Pilocytic astrocytoma + −
  • Glial cell origin
  • Solid and cystic component
  • GFAP +
Medulloblastoma + +
  • Neuroectoderm origin
  • Homer wright rosettes
Ependymoma + +
  • Ependymal cell origin
  • Perivascular pseudorosette
Craniopharyngioma + + Bitemporal hemianopia −
  • Ectodermal origin (Rathkes pouch)
  • Calcification +
Pinealoma + + vertical gaze palsy − +

B-hCG rise leads to precocious puberty in males

  • Similar to testicular seminoma
Vascular AV malformation + −
Brain aneurysm + −
Infectious Bacterial brain abscess + + −
Tuberculosis + + −
Toxoplasmosis + −
Hydatid cyst + −
Fungal + −
Other Brain metastasis + −

References

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