Merkel cell cancer laboratory tests: Difference between revisions
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{{CMG}} {{AE}} {{AAM}} | {{CMG}} {{AE}} {{AAM}} | ||
== | ==Overview== | ||
There are no laboratory findings associated with Merkel cell cancer. | There are no laboratory findings associated with Merkel cell cancer. | ||
==Laboratory findings== | ==Laboratory findings== | ||
Laboratory findings consistent with the diagnosis of merkel cell cancer include: | |||
'''Immunohistochemistry''' | |||
* [[Epithelial]] markers play an important role in the diagnosis of [[merkel cell cancer]] which include:<ref name="pmid18496143">{{cite journal |vauthors=Weinbreck N, Marie B, Bressenot A, Montagne K, Joud A, Baumann C, Klein O, Vignaud JM |title=Immunohistochemical markers to distinguish between hemangioblastoma and metastatic clear-cell renal cell carcinoma in the brain: utility of aquaporin1 combined with cytokeratin AE1/AE3 immunostaining |journal=Am. J. Surg. Pathol. |volume=32 |issue=7 |pages=1051–9 |date=July 2008 |pmid=18496143 |doi=10.1097/PAS.0b013e3181609d7d |url=}}</ref> | |||
** [[Cytokeratin]] AE1/AE3 | |||
** [[CAM]] 5.2 | |||
** Pan-[[cytokeratin]] | |||
** Epithelial membrane [[antigen]], and | |||
** Ber-EP4 | |||
'''Cytogenetic and molecular analysis''' | |||
==References== | ==References== | ||
Revision as of 00:27, 19 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
There are no laboratory findings associated with Merkel cell cancer.
Laboratory findings
Laboratory findings consistent with the diagnosis of merkel cell cancer include:
Immunohistochemistry
- Epithelial markers play an important role in the diagnosis of merkel cell cancer which include:[1]
- Cytokeratin AE1/AE3
- CAM 5.2
- Pan-cytokeratin
- Epithelial membrane antigen, and
- Ber-EP4
Cytogenetic and molecular analysis
References
- ↑ Weinbreck N, Marie B, Bressenot A, Montagne K, Joud A, Baumann C, Klein O, Vignaud JM (July 2008). "Immunohistochemical markers to distinguish between hemangioblastoma and metastatic clear-cell renal cell carcinoma in the brain: utility of aquaporin1 combined with cytokeratin AE1/AE3 immunostaining". Am. J. Surg. Pathol. 32 (7): 1051–9. doi:10.1097/PAS.0b013e3181609d7d. PMID 18496143.