Pleomorphic adenoma classification: Difference between revisions
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==Classification== | ==Classification== | ||
*Pleomorphic adenoma can be classified on the | *Pleomorphic adenoma can be classified based on the stromal content of the tumor into the following subgroups.<ref name="pmid1002574">{{cite journal |vauthors=Seifert G, Langrock I, Donath K |title=[A pathological classification of pleomorphic adenoma of the salivary glands (author's transl)] |language=German |journal=HNO |volume=24 |issue=12 |pages=415–26 |date=December 1976 |pmid=1002574 |doi= |url=}}</ref> | ||
**Subgroup 1 | **Subgroup 1 is the classical pleomorphic adenoma with a stroma content of 30-50% | ||
**subgroup 2 | **subgroup 2 has a stroma content of 80% | ||
**subgroup 3 | **subgroup 3 has a poor stroma content of 20-30% or less and an epithelial differentiation similar to subgroup 1 | ||
**subgroup 4 has also a poor stroma content (6%) with a relatively monomorphic epithelial structure. | **subgroup 4 has also a poor stroma content (6%) with a relatively monomorphic epithelial structure. | ||
*Depending upon which | *Depending upon which component predominates pleomorphic adenoma can also be classified into:<ref name="ZhanKhaja2016">{{cite journal|last1=Zhan|first1=Kevin Y.|last2=Khaja|first2=Sobia F.|last3=Flack|first3=Allen B.|last4=Day|first4=Terry A.|title=Benign Parotid Tumors|journal=Otolaryngologic Clinics of North America|volume=49|issue=2|year=2016|pages=327–342|issn=00306665|doi=10.1016/j.otc.2015.10.005}}</ref> | ||
**Cellular(either epithelial or myoepithelial cell rich) | **Cellular(either epithelial or myoepithelial cell rich) | ||
**Stroma-rich | **Stroma-rich | ||
Revision as of 17:56, 22 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Pleomorphic adenoma can be classified into 4 subgroups on the basis of histological appearance and stromal content. Subgroup 1(30-50%) of stromal content, subgroup 2(80%), subgroup 3(20-30%), subgroup 4(6%).
Classification
- Pleomorphic adenoma can be classified based on the stromal content of the tumor into the following subgroups.[1]
- Subgroup 1 is the classical pleomorphic adenoma with a stroma content of 30-50%
- subgroup 2 has a stroma content of 80%
- subgroup 3 has a poor stroma content of 20-30% or less and an epithelial differentiation similar to subgroup 1
- subgroup 4 has also a poor stroma content (6%) with a relatively monomorphic epithelial structure.
- Depending upon which component predominates pleomorphic adenoma can also be classified into:[2]
- Cellular(either epithelial or myoepithelial cell rich)
- Stroma-rich
- Mixed type or classic
References
- ↑ Seifert G, Langrock I, Donath K (December 1976). "[A pathological classification of pleomorphic adenoma of the salivary glands (author's transl)]". HNO (in German). 24 (12): 415–26. PMID 1002574.
- ↑ Zhan, Kevin Y.; Khaja, Sobia F.; Flack, Allen B.; Day, Terry A. (2016). "Benign Parotid Tumors". Otolaryngologic Clinics of North America. 49 (2): 327–342. doi:10.1016/j.otc.2015.10.005. ISSN 0030-6665.