Mucoepidermoid carcinoma surgery: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Mucoepidermoid carcinoma}} | {{Mucoepidermoid carcinoma}} | ||
{{CMG}}{{AE}}{{MV}} | {{CMG}}{{AE}}{{Badria}} , {{MV}} | ||
==Overview== | ==Overview== | ||
Surgery is the mainstay of therapy for mucoepidermoid carcinoma. | Surgery is the mainstay of therapy for mucoepidermoid carcinoma. | ||
==Surgery== | ==Surgery== | ||
*Mucoepidermoid carcinoma (low-grade): complete surgical excision with sparing of the facial nerve.<ref name="ppp"> Mucoepidermoid Carcinoma Surgery. WikiBooks. https://en.wikibooks.org/wiki/Radiation_Oncology/Head_%26_Neck/Salivary_gland Accessed on February 17,2016</ref> | *Mucoepidermoid carcinoma (low-grade): complete surgical excision with sparing of the facial nerve.<ref name="ppp"> Mucoepidermoid Carcinoma Surgery. WikiBooks. https://en.wikibooks.org/wiki/Radiation_Oncology/Head_%26_Neck/Salivary_gland Accessed on February 17,2016</ref><ref name="ppp"> Mucoepidermoid Carcinoma Surgery. WikiBooks. https://en.wikibooks.org/wiki/Radiation_Oncology/Head_%26_Neck/Salivary_gland Accessed on February 17,2016</ref> | ||
*Mucoepidermoid carcinoma (high-grade): parotidectomy with facial nerve sparing may be followed by radiotherapy. | *Mucoepidermoid carcinoma (high-grade): parotidectomy with facial nerve sparing may be followed by radiotherapy. | ||
*Clinically aggressive mucoepidermoid carcinoma tumors with facial nerve involvement will require radical surgery with sacrifice of the facial nerve and radiotherapy. <ref name="pmid29318070">{{cite journal |vauthors=Gedar Totuk OM, Demir MK, Yapicier O, Mestanoglu M |title=Low-Grade Mucoepidermoid Carcinoma of the Lacrimal Gland in a Teenaged Patient |journal=Case Rep Ophthalmol Med |volume=2017 |issue= |pages=2418505 |date=2017 |pmid=29318070 |pmc=5727657 |doi=10.1155/2017/2418505 |url=}}</ref> | *Clinically aggressive mucoepidermoid carcinoma tumors with facial nerve involvement will require radical surgery with sacrifice of the facial nerve and radiotherapy. <ref name="pmid29318070">{{cite journal |vauthors=Gedar Totuk OM, Demir MK, Yapicier O, Mestanoglu M |title=Low-Grade Mucoepidermoid Carcinoma of the Lacrimal Gland in a Teenaged Patient |journal=Case Rep Ophthalmol Med |volume=2017 |issue= |pages=2418505 |date=2017 |pmid=29318070 |pmc=5727657 |doi=10.1155/2017/2418505 |url=}}</ref> | ||
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*Lymph node dissection is usually only performed for clinically or radiographically detected nodal metastasis. | *Lymph node dissection is usually only performed for clinically or radiographically detected nodal metastasis. | ||
* Low grade mucoepidermoid carcinoma in the floor of the mouth can be surgically excised along with involved [[lymph node]]. | |||
<ref name="pmid14662408">{{cite journal |vauthors=Rinaldo A, Shaha AR, Pellitteri PK, Bradley PJ, Ferlito A |title=Management of malignant sublingual salivary gland tumors |journal=Oral Oncol. |volume=40 |issue=1 |pages=2–5 |date=January 2004 |pmid=14662408 |doi= |url=}}</ref> | <ref name="pmid14662408">{{cite journal |vauthors=Rinaldo A, Shaha AR, Pellitteri PK, Bradley PJ, Ferlito A |title=Management of malignant sublingual salivary gland tumors |journal=Oral Oncol. |volume=40 |issue=1 |pages=2–5 |date=January 2004 |pmid=14662408 |doi= |url=}}</ref> | ||
The treatment measures for MEC of Salivary Gland may involve:<ref name="pmid9261001">{{cite journal |vauthors=Helmus C |title=Subtotal parotidectomy: a 10-year review (1985 to 1994) |journal=Laryngoscope |volume=107 |issue=8 |pages=1024–7 |date=August 1997 |pmid=9261001 |doi= |url=}}</ref> | |||
* When the tumor is at an inaccessible location, clinical trial therapies (especially for stage IV disease) including therapeutic drugs, radiation, stem cell transplantation, and monoclonal antibodies, either singly or in combination of various therapies | |||
* Follow-up care with regular screening and check-ups are important, to watch for recurrence and any metastatic behavior<ref name="pmid26813873">{{cite journal |vauthors=Maloth AK, Nandan SR, Kulkarni PG, Dorankula SP, Muddana K |title=Mucoepidermoid Carcinoma of Floor of the Mouth - A Rarity |journal=J Clin Diagn Res |volume=9 |issue=12 |pages=ZD03–4 |date=December 2015 |pmid=26813873 |pmc=4717804 |doi=10.7860/JCDR/2015/15595.6912 |url=}}</ref> | |||
==Indications== | ==Indications== | ||
Revision as of 19:44, 22 January 2019
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Mucoepidermoid carcinoma Microchapters |
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Differentiating Mucoepidermoid Carcinoma from other Diseases |
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Diagnosis |
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Case Studies |
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Mucoepidermoid carcinoma surgery On the Web |
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American Roentgen Ray Society Images of Mucoepidermoid carcinoma surgery |
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Risk calculators and risk factors for Mucoepidermoid carcinoma surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Badria Munir M.B.B.S.[2] , Maria Fernanda Villarreal, M.D. [3]
Overview
Surgery is the mainstay of therapy for mucoepidermoid carcinoma.
Surgery
- Mucoepidermoid carcinoma (low-grade): complete surgical excision with sparing of the facial nerve.[1][1]
- Mucoepidermoid carcinoma (high-grade): parotidectomy with facial nerve sparing may be followed by radiotherapy.
- Clinically aggressive mucoepidermoid carcinoma tumors with facial nerve involvement will require radical surgery with sacrifice of the facial nerve and radiotherapy. [2]
- Primary nerve grafting using the sural nerve if possible is performed.
- Lymph node dissection is usually only performed for clinically or radiographically detected nodal metastasis.
- Low grade mucoepidermoid carcinoma in the floor of the mouth can be surgically excised along with involved lymph node.
[3] The treatment measures for MEC of Salivary Gland may involve:[4]
- When the tumor is at an inaccessible location, clinical trial therapies (especially for stage IV disease) including therapeutic drugs, radiation, stem cell transplantation, and monoclonal antibodies, either singly or in combination of various therapies
- Follow-up care with regular screening and check-ups are important, to watch for recurrence and any metastatic behavior[5]
Indications
- Indications for surgery for mucoepidermoid carcinoma, include:[6]
- Biological and histological features suitable for surgery
Gallery
{{#ev:youtube|20sj0dJI6Xg}}
References
- ↑ 1.0 1.1 Mucoepidermoid Carcinoma Surgery. WikiBooks. https://en.wikibooks.org/wiki/Radiation_Oncology/Head_%26_Neck/Salivary_gland Accessed on February 17,2016
- ↑ Gedar Totuk OM, Demir MK, Yapicier O, Mestanoglu M (2017). "Low-Grade Mucoepidermoid Carcinoma of the Lacrimal Gland in a Teenaged Patient". Case Rep Ophthalmol Med. 2017: 2418505. doi:10.1155/2017/2418505. PMC 5727657. PMID 29318070.
- ↑ Rinaldo A, Shaha AR, Pellitteri PK, Bradley PJ, Ferlito A (January 2004). "Management of malignant sublingual salivary gland tumors". Oral Oncol. 40 (1): 2–5. PMID 14662408.
- ↑ Helmus C (August 1997). "Subtotal parotidectomy: a 10-year review (1985 to 1994)". Laryngoscope. 107 (8): 1024–7. PMID 9261001.
- ↑ Maloth AK, Nandan SR, Kulkarni PG, Dorankula SP, Muddana K (December 2015). "Mucoepidermoid Carcinoma of Floor of the Mouth - A Rarity". J Clin Diagn Res. 9 (12): ZD03–4. doi:10.7860/JCDR/2015/15595.6912. PMC 4717804. PMID 26813873.
- ↑ Rapidis, Alexander D.; Givalos, Nikolaos; Gakiopoulou, Hariklia; Stavrianos, Spyros D.; Faratzis, Gregory; Lagogiannis, George A.; Katsilieris, Ioannis; Patsouris, Efstratios (2007). "Mucoepidermoid carcinoma of the salivary glands". Oral Oncology. 43 (2): 130–136. doi:10.1016/j.oraloncology.2006.03.001. ISSN 1368-8375.