Pleomorphic adenoma other diagnostic studies: Difference between revisions
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==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
*Pleomorphic adenoma may also be diagnosed using [[fine needle aspiration]] (FNA) and core needle [[biopsy]]. | *Pleomorphic adenoma may also be diagnosed using [[fine needle aspiration]] (FNA) and core needle [[biopsy]]. | ||
*[[FNA]] can determine whether the tumor is [[malignant]] in nature with a [[sensitivity]] approximately 90%<ref>{{cite journal | | *[[FNA]] can determine whether the tumor is [[malignant]] in nature with a [[sensitivity]] approximately 90%<ref name="CohenPatel2004">{{cite journal|last1=Cohen|first1=Erik G.|last2=Patel|first2=Snehal G.|last3=Lin|first3=Oscar|last4=Boyle|first4=Jay O.|last5=Kraus|first5=Dennis H.|last6=Singh|first6=Bhuvanesh|last7=Wong|first7=Richard J.|last8=Shah|first8=Jatin P.|last9=Shaha|first9=Ashok R.|title=Fine-Needle Aspiration Biopsy of Salivary Gland Lesions in a Selected Patient Population|journal=Archives of Otolaryngology–Head & Neck Surgery|volume=130|issue=6|year=2004|pages=773|issn=0886-4470|doi=10.1001/archotol.130.6.773}}</ref> | ||
*FNA can also distinguish primary salivary tumor from [[metastatic]] disease | *FNA can also distinguish primary salivary tumor from [[metastatic]] disease | ||
*Core needle [[biopsy]] is more accurate compared to [[FNA]] with diagnostic [[accuracy]] greater than 97%<ref>{{cite journal |author=Wan YL, Chan SC, Chen YL, ''et al'' |title=Ultrasonography-guided core-needle biopsy of parotid gland masses |journal=AJNR Am J Neuroradiol |volume=25 |issue=9 |pages=1608–12 |year=2004 |month=Oct |pmid=15502149 |doi= |url=http://www.ajnr.org/cgi/pmidlookup?view=long&pmid=15502149}}</ref> | *Core needle [[biopsy]] is more accurate compared to [[FNA]] with diagnostic [[accuracy]] greater than 97%<ref>{{cite journal |author=Wan YL, Chan SC, Chen YL, ''et al'' |title=Ultrasonography-guided core-needle biopsy of parotid gland masses |journal=AJNR Am J Neuroradiol |volume=25 |issue=9 |pages=1608–12 |year=2004 |month=Oct |pmid=15502149 |doi= |url=http://www.ajnr.org/cgi/pmidlookup?view=long&pmid=15502149}}</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
The other diagnostic studies available for pleomorphic adenoma are FNA and core biopsy.
Other Diagnostic Studies
- Pleomorphic adenoma may also be diagnosed using fine needle aspiration (FNA) and core needle biopsy.
- FNA can determine whether the tumor is malignant in nature with a sensitivity approximately 90%[1]
- FNA can also distinguish primary salivary tumor from metastatic disease
- Core needle biopsy is more accurate compared to FNA with diagnostic accuracy greater than 97%[2]
- Findings on fine needle aspiration (FNA) and core needle biopsy, include:
- Admixture of polygonal epithelial and spindle-shaped myoepithelial elements
- Mesenchymal stroma (important feature)
- Proliferation of myoepithelium and epithelium
References
- ↑ Cohen, Erik G.; Patel, Snehal G.; Lin, Oscar; Boyle, Jay O.; Kraus, Dennis H.; Singh, Bhuvanesh; Wong, Richard J.; Shah, Jatin P.; Shaha, Ashok R. (2004). "Fine-Needle Aspiration Biopsy of Salivary Gland Lesions in a Selected Patient Population". Archives of Otolaryngology–Head & Neck Surgery. 130 (6): 773. doi:10.1001/archotol.130.6.773. ISSN 0886-4470.
- ↑ Wan YL, Chan SC, Chen YL; et al. (2004). "Ultrasonography-guided core-needle biopsy of parotid gland masses". AJNR Am J Neuroradiol. 25 (9): 1608–12. PMID 15502149. Unknown parameter
|month=ignored (help)