Sandbox:Maneesha: Difference between revisions

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==Epidemiology and Demographics==
==Epidemiology and Demographics==


==Risk factors==
*Prior head and neck irradiation is a risk factor for the development of Pleomorphic adenoma.<ref name="pmid30028745">{{cite journal |vauthors=Gündüz AK, Yeşiltaş YS, Shields CL |title=Overview of benign and malignant lacrimal gland tumors |journal=Curr Opin Ophthalmol |volume=29 |issue=5 |pages=458–468 |date=September 2018 |pmid=30028745 |doi=10.1097/ICU.0000000000000515 |url=}}</ref>
*Environmental factors
*Occupations like working in rubber industry, nickel industry etc.<ref name="pmid9279445">{{cite journal |vauthors=Swanson GM, Burns PB |title=Cancers of the salivary gland: workplace risks among women and men |journal=Ann Epidemiol |volume=7 |issue=6 |pages=369–74 |date=August 1997 |pmid=9279445 |doi= |url=}}</ref><ref name="pmid9209856">{{cite journal |vauthors=Horn-Ross PL, Ljung BM, Morrow M |title=Environmental factors and the risk of salivary gland cancer |journal=Epidemiology |volume=8 |issue=4 |pages=414–9 |date=July 1997 |pmid=9209856 |doi= |url=}}</ref>
==Classification==
==Classification==
*Pleomorphic adenoma can be classified on the basis of the histological appearance i.e, epithelial and stromal changes into the following subgroups.<ref name="pmid1002574">{{cite journal |vauthors=Seifert G, Langrock I, Donath K |title=[A pathological classification of pleomorphic adenoma of the salivary glands (author's transl)] |language=German |journal=HNO |volume=24 |issue=12 |pages=415–26 |date=December 1976 |pmid=1002574 |doi= |url=}}</ref>  
*Pleomorphic adenoma can be classified on the basis of the histological appearance i.e, epithelial and stromal changes into the following subgroups.<ref name="pmid1002574">{{cite journal |vauthors=Seifert G, Langrock I, Donath K |title=[A pathological classification of pleomorphic adenoma of the salivary glands (author's transl)] |language=German |journal=HNO |volume=24 |issue=12 |pages=415–26 |date=December 1976 |pmid=1002574 |doi= |url=}}</ref>  

Revision as of 18:16, 23 January 2019


Epidemiology and Demographics

Classification

  • Pleomorphic adenoma can be classified on the basis of the histological appearance i.e, epithelial and stromal changes into the following subgroups.[1]
    • Subgroup 1 (30,5%) is the classical pleomorphic adenoma with a stroma content of 30-50%
    • subgroup 2 (55%) has a stroma content of 80%
    • subgroup 3 (9%) has a poor stroma content of 20-30% or less and an epithelial differentiation similar to subgroup 1
    • subgroup 4 has also a poor stroma content (6%) with a relatively monomorphic epithelial structure.

Natural history, Complications and Prognosis

Natural history

References

  1. Seifert G, Langrock I, Donath K (December 1976). "[A pathological classification of pleomorphic adenoma of the salivary glands (author's transl)]". HNO (in German). 24 (12): 415–26. PMID 1002574.