Diabetes insipidus Diagnostic study of choice: Difference between revisions
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=== Diagnostic approach === | === Diagnostic approach === | ||
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Revision as of 20:12, 24 January 2019
Diabetes insipidus Microchapters |
Diagnosis |
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Treatment |
Case Studies |
Diabetes insipidus Diagnostic study of choice On the Web |
American Roentgen Ray Society Images of Diabetes insipidus Diagnostic study of choice |
Risk calculators and risk factors for Diabetes insipidus Diagnostic study of choice |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Trusha Tank, M.D.[2]
Overview
Diagnostic Study of Choice
Diagnostic approach
Clinical exam, signs, symptoms | |||||||||||||||||||||||||||||||||||||||
24-hrs water balance: •Confirm polyurea and polydipsia | |||||||||||||||||||||||||||||||||||||||
24-hrs urine volume: • >50-60 ml/kg (age 0-10) • >40-50 ml/kg (age >10) | |||||||||||||||||||||||||||||||||||||||
Blood and urine test (Na+, Posm, Uosm) | Other diagnostic hypothesis | ||||||||||||||||||||||||||||||||||||||
• Plasma Na+ >143 mEq/L • Posm >295 mOsm/kg H2O • Uosm < Posm | • Plasma Na+ <143 mEq/L • Posm <295 mOsm/kg H2O • Uosm < Posm | ||||||||||||||||||||||||||||||||||||||
Water deprivation test (minimum for 7 hrs) • Monitor body wt, Posm, Uosm, plasma AVP • Inturrept and measure AVP/Copeptin if; • >3-5% body wt loss • Plasma Na+ > 143 mEq/L • Posm >295 mOsm/kg H2O • Uosm increases to normal | |||||||||||||||||||||||||||||||||||||||