Pleomorphic adenoma other diagnostic studies: Difference between revisions
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*Pleomorphic adenoma may also be diagnosed using [[fine needle aspiration]] (FNA) and core needle [[biopsy]]. | *Pleomorphic adenoma may also be diagnosed using [[fine needle aspiration]] (FNA) and core needle [[biopsy]]. | ||
*[[FNA]] can determine whether the [[tumor]] is [[malignant]] in nature with a [[sensitivity]] approximately 90%<ref name="BatsakisSneige2016">{{cite journal|last1=Batsakis|first1=John G.|last2=Sneige|first2=Nour|last3=El-Naggar|first3=Adel K.|title=Fine-Needle Aspiration of Salivary Glands: Its Utility and Tissue Effects|journal=Annals of Otology, Rhinology & Laryngology|volume=101|issue=2|year=2016|pages=185–188|issn=0003-4894|doi=10.1177/000348949210100215}}</ref> | *[[FNA]] can determine whether the [[tumor]] is [[malignant]] in nature with a [[sensitivity]] approximately 90%<ref name="BatsakisSneige2016">{{cite journal|last1=Batsakis|first1=John G.|last2=Sneige|first2=Nour|last3=El-Naggar|first3=Adel K.|title=Fine-Needle Aspiration of Salivary Glands: Its Utility and Tissue Effects|journal=Annals of Otology, Rhinology & Laryngology|volume=101|issue=2|year=2016|pages=185–188|issn=0003-4894|doi=10.1177/000348949210100215}}</ref> | ||
*FNA can also distinguish primary salivary tumor from [[metastatic]] disease. | *[[FNA]] can also distinguish primary salivary tumor from [[metastatic]] [[disease]]. | ||
*Core needle [[biopsy]] is more accurate compared to [[FNA]] with diagnostic [[accuracy]] greater than 97%<ref name="KesseManjaly2002">{{cite journal|last1=Kesse|first1=K.W|last2=Manjaly|first2=G|last3=Violaris|first3=N|last4=Howlett|first4=D.C|title=Ultrasound-guided biopsy in the evaluation of focal lesions and diffuse swelling of the parotid gland|journal=British Journal of Oral and Maxillofacial Surgery|volume=40|issue=5|year=2002|pages=384–388|issn=02664356|doi=10.1016/S0266-4356(02)00189-4}}</ref> | *Core needle [[biopsy]] is more accurate compared to [[FNA]] with diagnostic [[accuracy]] greater than 97%<ref name="KesseManjaly2002">{{cite journal|last1=Kesse|first1=K.W|last2=Manjaly|first2=G|last3=Violaris|first3=N|last4=Howlett|first4=D.C|title=Ultrasound-guided biopsy in the evaluation of focal lesions and diffuse swelling of the parotid gland|journal=British Journal of Oral and Maxillofacial Surgery|volume=40|issue=5|year=2002|pages=384–388|issn=02664356|doi=10.1016/S0266-4356(02)00189-4}}</ref> | ||
*Findings on [[fine needle aspiration]] (FNA) and core needle biopsy, include: | *Findings on [[fine needle aspiration]] (FNA) and core needle biopsy, include: | ||
:*Admixture of polygonal epithelial and spindle-shaped myoepithelial elements | :*Admixture of polygonal [[epithelial]] and spindle-shaped [[myoepithelial]] elements | ||
:*[[Mesenchyme|Mesenchymal stroma]] (important feature) | :*[[Mesenchyme|Mesenchymal stroma]] (important feature) | ||
:*Proliferation of [[Myoepithelial cells|myoepithelium]] and [[epithelium]] | :*[[Proliferation]] of [[Myoepithelial cells|myoepithelium]] and [[epithelium]] | ||
==References== | ==References== | ||
Revision as of 16:51, 28 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
The other diagnostic studies available for pleomorphic adenoma are FNA and core biopsy.
Other Diagnostic Studies
- Pleomorphic adenoma may also be diagnosed using fine needle aspiration (FNA) and core needle biopsy.
- FNA can determine whether the tumor is malignant in nature with a sensitivity approximately 90%[1]
- FNA can also distinguish primary salivary tumor from metastatic disease.
- Core needle biopsy is more accurate compared to FNA with diagnostic accuracy greater than 97%[2]
- Findings on fine needle aspiration (FNA) and core needle biopsy, include:
- Admixture of polygonal epithelial and spindle-shaped myoepithelial elements
- Mesenchymal stroma (important feature)
- Proliferation of myoepithelium and epithelium
References
- ↑ Batsakis, John G.; Sneige, Nour; El-Naggar, Adel K. (2016). "Fine-Needle Aspiration of Salivary Glands: Its Utility and Tissue Effects". Annals of Otology, Rhinology & Laryngology. 101 (2): 185–188. doi:10.1177/000348949210100215. ISSN 0003-4894.
- ↑ Kesse, K.W; Manjaly, G; Violaris, N; Howlett, D.C (2002). "Ultrasound-guided biopsy in the evaluation of focal lesions and diffuse swelling of the parotid gland". British Journal of Oral and Maxillofacial Surgery. 40 (5): 384–388. doi:10.1016/S0266-4356(02)00189-4. ISSN 0266-4356.