Acute lymphoblastic leukemia risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Carlos A Lopez, M.D. [3]

Overview

Common risk factors in the development of acute lymphoblastic leukemia are Down syndrome, ataxia telangiectasia, Bloom syndrome, X-linked agammaglobulinemia, Fanconi's anemia and severe combined immunodeficiency.

Risk Factors

Common risk factors in the development of acute lymphoblastic leukemia are Down syndrome, ataxia telangiectasia, Bloom syndrome, X-linked agammaglobulinemia, Fanconi's anemia severe combined immunodeficiency, Radiation exposure, exposure to benzene, and smoking.

Common risk factors

Acute lymphoblastic leukemia risk factors may include the following:

• Radiation exposure
• Benzene exposure
• Infections with the following viruses
  • EBV
  • HTLV-1
• Previous use of chemotherapy drugs
• Smoking
• Down syndrome
• Ataxia telangiectasia
• Bloom syndrome
• X-linked agammaglobulinemia
• Fanconi's anemia
• Severe combined immunodeficiency