Merkel cell cancer epidemiology and demographics: Difference between revisions

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Revision as of 02:24, 31 January 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2] Ahmad Al Maradni, M.D. [3]

Overview

The incidence of merkel cell carcinoma ranges from 0.5 per 100,000 individuals. The median age at diagnosis is approximately 65 years. Merkel cell carcinoma is more common among males and individuals of the caucasian race.

Epidemiology and Demographics

Incidence

The incidence of merkel cell carcinoma ranges from 0.5 per 100,000 individuals.^[1]^[2]
The incidence is thought to have tripled between 1986 and 2001.
According to the new research incidence rates are reportedly increasing in Australia and New Zealand.^[3]^[4]
By 2020, the incidenceof merkel cell carcinoma was estimated to be 2835 cases in the United States.^[5]
By 2035, the incidenceof merkel cell carcinoma was estimated to be 3284 cases in the United States.^[6]

Age

Merkel cell carcinoma incidence increases progressively with age.^[7]
The majority of patients with merkel cell carcinoma are diagnosed at age > 50 years.^[7]
The median age at diagnosis is approximately 65 years.^[8]

Gender

Merkel cell carcinomar is slightly more common among males than females.^[7]

Race

Merkel cell carcinoma is much more common among individuals of the Caucasian race compared to individuals of other ethnicities.^[7]

References

↑ Girschik J, Thorn K, Beer TW, Heenan PJ, Fritschi L (November 2011). "Merkel cell carcinoma in Western Australia: a population-based study of incidence and survival". Br. J. Dermatol. 165 (5): 1051–7. doi:10.1111/j.1365-2133.2011.10493.x. PMID 21711338.
↑ Kieny A, Cribier B, Meyer N, Velten M, Jégu J, Lipsker D (February 2019). "Epidemiology of Merkel cell carcinoma. A population-based study from 1985 to 2013, in northeastern of France". Int. J. Cancer. 144 (4): 741–745. doi:10.1002/ijc.31860. PMID 30194728.
↑ Girschik J, Thorn K, Beer TW, Heenan PJ, Fritschi L (November 2011). "Merkel cell carcinoma in Western Australia: a population-based study of incidence and survival". Br. J. Dermatol. 165 (5): 1051–7. doi:10.1111/j.1365-2133.2011.10493.x. PMID 21711338.
↑ Youlden DR, Soyer HP, Youl PH, Fritschi L, Baade PD (August 2014). "Incidence and survival for Merkel cell carcinoma in Queensland, Australia, 1993-2010". JAMA Dermatol. 150 (8): 864–72. doi:10.1001/jamadermatol.2014.124. PMID 24943712.
↑ Paulson KG, Park SY, Vandeven NA, Lachance K, Thomas H, Chapuis AG, Harms KL, Thompson JA, Bhatia S, Stang A, Nghiem P (March 2018). "Merkel cell carcinoma: Current US incidence and projected increases based on changing demographics". J. Am. Acad. Dermatol. 78 (3): 457–463.e2. doi:10.1016/j.jaad.2017.10.028. PMID 29102486.
↑ Paulson KG, Park SY, Vandeven NA, Lachance K, Thomas H, Chapuis AG, Harms KL, Thompson JA, Bhatia S, Stang A, Nghiem P (March 2018). "Merkel cell carcinoma: Current US incidence and projected increases based on changing demographics". J. Am. Acad. Dermatol. 78 (3): 457–463.e2. doi:10.1016/j.jaad.2017.10.028. PMID 29102486.
↑ ^7.0 ^7.1 ^7.2 ^7.3 Heath M, Jaimes N, Lemos B, Mostaghimi A, Wang LC, Peñas PF; et al. (2008). "Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features". J Am Acad Dermatol. 58 (3): 375–81. doi:10.1016/j.jaad.2007.11.020. PMC 2335370. PMID 18280333.
↑ National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdp

Template:WikiDoc Sources

[pmid217113382-1] Girschik J, Thorn K, Beer TW, Heenan PJ, Fritschi L (November 2011). "Merkel cell carcinoma in Western Australia: a population-based study of incidence and survival". Br. J. Dermatol. 165 (5): 1051–7. doi:10.1111/j.1365-2133.2011.10493.x. PMID 21711338.

[pmid30194728-2] Kieny A, Cribier B, Meyer N, Velten M, Jégu J, Lipsker D (February 2019). "Epidemiology of Merkel cell carcinoma. A population-based study from 1985 to 2013, in northeastern of France". Int. J. Cancer. 144 (4): 741–745. doi:10.1002/ijc.31860. PMID 30194728.

[pmid21711338-3] Girschik J, Thorn K, Beer TW, Heenan PJ, Fritschi L (November 2011). "Merkel cell carcinoma in Western Australia: a population-based study of incidence and survival". Br. J. Dermatol. 165 (5): 1051–7. doi:10.1111/j.1365-2133.2011.10493.x. PMID 21711338.

[pmid24943712-4] Youlden DR, Soyer HP, Youl PH, Fritschi L, Baade PD (August 2014). "Incidence and survival for Merkel cell carcinoma in Queensland, Australia, 1993-2010". JAMA Dermatol. 150 (8): 864–72. doi:10.1001/jamadermatol.2014.124. PMID 24943712.

[pmid29102486-5] Paulson KG, Park SY, Vandeven NA, Lachance K, Thomas H, Chapuis AG, Harms KL, Thompson JA, Bhatia S, Stang A, Nghiem P (March 2018). "Merkel cell carcinoma: Current US incidence and projected increases based on changing demographics". J. Am. Acad. Dermatol. 78 (3): 457–463.e2. doi:10.1016/j.jaad.2017.10.028. PMID 29102486.

[pmid291024862-6] Paulson KG, Park SY, Vandeven NA, Lachance K, Thomas H, Chapuis AG, Harms KL, Thompson JA, Bhatia S, Stang A, Nghiem P (March 2018). "Merkel cell carcinoma: Current US incidence and projected increases based on changing demographics". J. Am. Acad. Dermatol. 78 (3): 457–463.e2. doi:10.1016/j.jaad.2017.10.028. PMID 29102486.

[pmid18280333-7] 7.0 ^7.1 ^7.2 ^7.3 Heath M, Jaimes N, Lemos B, Mostaghimi A, Wang LC, Peñas PF; et al. (2008). "Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features". J Am Acad Dermatol. 58 (3): 375–81. doi:10.1016/j.jaad.2007.11.020. PMC 2335370. PMID 18280333.

[cancergov-8] National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdp

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 ==Overview==
-The incidence of [[merkel cell carcinoma]] ranges from 0.5 per 100,000 individuals. The median age at diagnosis is approximately 65 years. [[Merkel cell carcinoma]] is more common among males and individuals of the Caucasian race.
+The incidence of merkel cell carcinoma ranges from 0.5 per 100,000 individuals. The [[median]] age at diagnosis is approximately 65 years. Merkel cell carcinoma is more common among males and individuals of the caucasian race.
 ==Epidemiology and Demographics==