Waldenström's macroglobulinemia: Difference between revisions
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==[[Diagnosis]]== | ==[[Diagnosis]]== | ||
Not all the diagnostic tests mentioned are performed in a WM patient. A doctor takes into account the following factors before choosing diagnostic tests in a particular patient: | ==Diagnostic criteria of Waldenstrom Macroglobulinemia== | ||
*Suspected type of cancer. | In September 26-30, 2002, in Athens, Greece,the Second International Workshop was held in which the following diagnostic criteria for Waldenstrom's Macroglobulinemia was proposed: | ||
*Signs and symptoms. | #IgM monoclonal protein of any concentration. | ||
*Age. | #Bone marrow infiltration by small lymphocytes showing plasmacytoid/plasma-cell differentiation. | ||
*Medical condition of the patient. | #Intertrabecular pattern of bone marrow infiltration. | ||
*Results of earlier medical tests. | #Surface IgM+, CD5±, CD10−, CD19+, CD20+, CD22+, CD23−, CD25+, CD27+, FMC7+, CD103−, CD138 immunophenotype. | ||
*Not all the diagnostic tests mentioned are performed in a WM patient. A doctor takes into account the following factors before choosing diagnostic tests in a particular patient: | |||
**Suspected type of cancer. | |||
**Signs and symptoms. | |||
**Age. | |||
**Medical condition of the patient. | |||
**Results of earlier medical tests. | |||
[[Waldenström's macroglobulinemia diagnostic study of choice|Diagnostic Study of Choice]] | [[Waldenström's macroglobulinemia history and symptoms|History and Symptoms]] | [[Waldenström's macroglobulinemia physical examination|Physical Examination]] | [[Waldenström's macroglobulinemia laboratory findings|Laboratory Findings]] | [[Waldenström's macroglobulinemia electrocardiogram|Electrocardiogram]] | [[Waldenström's macroglobulinemia chest x ray|Chest X Ray]] | [[Waldenström's macroglobulinemia CT|CT]] | [[Waldenström's macroglobulinemia MRI|MRI]] | [[Waldenström's macroglobulinemia Electrocardiography or Ultrasound|Electrocardiography or Ultrasound]] | [[Waldenström's macroglobulinemia Other Imaging Findings|Other Imaging Findings]] | [[Waldenström's macroglobulinemia Other Diagnostic Studies|Other Diagnostic Studies]] | [[Waldenström's macroglobulinemia diagnostic study of choice|Diagnostic Study of Choice]] | [[Waldenström's macroglobulinemia history and symptoms|History and Symptoms]] | [[Waldenström's macroglobulinemia physical examination|Physical Examination]] | [[Waldenström's macroglobulinemia laboratory findings|Laboratory Findings]] | [[Waldenström's macroglobulinemia electrocardiogram|Electrocardiogram]] | [[Waldenström's macroglobulinemia chest x ray|Chest X Ray]] | [[Waldenström's macroglobulinemia CT|CT]] | [[Waldenström's macroglobulinemia MRI|MRI]] | [[Waldenström's macroglobulinemia Electrocardiography or Ultrasound|Electrocardiography or Ultrasound]] | [[Waldenström's macroglobulinemia Other Imaging Findings|Other Imaging Findings]] | [[Waldenström's macroglobulinemia Other Diagnostic Studies|Other Diagnostic Studies]] | ||
Revision as of 16:53, 6 February 2019
Waldenström's macroglobulinemia Microchapters |
Differentiating Waldenström's macroglobulinemia from other Diseases |
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Diagnosis |
Treatment |
Case Studies |
Waldenström's macroglobulinemia On the Web |
American Roentgen Ray Society Images of Waldenström's macroglobulinemia |
Directions to Hospitals Treating Waldenström's macroglobulinemia |
Risk calculators and risk factors for Waldenström's macroglobulinemia |
For patient information on this page, click here Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2] Roukoz A. Karam, M.D.[3], Mirdula Sharma, MBBS [4]
Synonyms and keywords: Waldenstrom/Waldenstrom's macroglubulinemia (WM), Primary macroglobulinemia, Lymphoplasmacytic lymphoma (LPL), Plasmacytoid lymphocytic lymphoma, Familial Waldenstrom's Macroglobulinaemia, Waldenström macroglobulinaemia
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Waldenström's Macroglobulinemia from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic criteria of Waldenstrom Macroglobulinemia
In September 26-30, 2002, in Athens, Greece,the Second International Workshop was held in which the following diagnostic criteria for Waldenstrom's Macroglobulinemia was proposed:
- IgM monoclonal protein of any concentration.
- Bone marrow infiltration by small lymphocytes showing plasmacytoid/plasma-cell differentiation.
- Intertrabecular pattern of bone marrow infiltration.
- Surface IgM+, CD5±, CD10−, CD19+, CD20+, CD22+, CD23−, CD25+, CD27+, FMC7+, CD103−, CD138 immunophenotype.
- Not all the diagnostic tests mentioned are performed in a WM patient. A doctor takes into account the following factors before choosing diagnostic tests in a particular patient:
- Suspected type of cancer.
- Signs and symptoms.
- Age.
- Medical condition of the patient.
- Results of earlier medical tests.
Diagnostic Study of Choice | History and Symptoms | Physical Examination | Laboratory Findings | Electrocardiogram | Chest X Ray | CT | MRI | Electrocardiography or Ultrasound | Other Imaging Findings | Other Diagnostic Studies
Treatment
Medical Therapy | Surgery | Cost-Effectiveness of Therapy | Future or Investigational Therapies
Case Studies