Craniopharyngioma differential diagnosis: Difference between revisions
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*[[Optic nerve glioma]] | *[[Optic nerve glioma]] | ||
General ''imaging differential'' considerations include:<ref name="pmid1260697">{{cite journal |vauthors=Petito CK, DeGirolami U, Earle KM |title=Craniopharyngiomas: a clinical and pathological review |journal=Cancer |volume=37 |issue=4 |pages=1944–52 |date=April 1976 |pmid=1260697 |doi= |url=}}</ref> <ref name="pmid9761047">{{cite journal |vauthors=Bunin GR, Surawicz TS, Witman PA, Preston-Martin S, Davis F, Bruner JM |title=The descriptive epidemiology of craniopharyngioma |journal=J. Neurosurg. |volume=89 |issue=4 |pages=547–51 |date=October 1998 |pmid=9761047 |doi=10.3171/jns.1998.89.4.0547 |url=}}</re | General ''imaging differential'' considerations include:<nowiki><ref name="pmid1260697"></nowiki>{{cite journal |vauthors=Petito CK, DeGirolami U, Earle KM |title=Craniopharyngiomas: a clinical and pathological review |journal=Cancer |volume=37 |issue=4 |pages=1944–52 |date=April 1976 |pmid=1260697 |doi= |url=}}</ref> <ref name="pmid9761047">{{cite journal |vauthors=Bunin GR, Surawicz TS, Witman PA, Preston-Martin S, Davis F, Bruner JM |title=The descriptive epidemiology of craniopharyngioma |journal=J. Neurosurg. |volume=89 |issue=4 |pages=547–51 |date=October 1998 |pmid=9761047 |doi=10.3171/jns.1998.89.4.0547 |url=}}</re | ||
*'''Rathke cleft cyst''' | *'''Rathke cleft cyst''' | ||
**No solid or enhancing component | **No solid or enhancing component | ||
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**Presence of fat is helpful, but requires fat saturated sequences or CT to confirm | **Presence of fat is helpful, but requires fat saturated sequences or CT to confirm | ||
Craniopharyngioma must be differentiated from other causes of diabetes insipidus.<ref name="pmid1260697">{{cite journal |vauthors=Petito CK, DeGirolami U, Earle KM |title=Craniopharyngiomas: a clinical and pathological review |journal=Cancer |volume=37 |issue=4 |pages=1944–52 |date=April 1976 |pmid=1260697 |doi= |url=}}</ref> | Craniopharyngioma must be differentiated from other causes of diabetes insipidus.<nowiki><ref name="pmid1260697"></nowiki>{{cite journal |vauthors=Petito CK, DeGirolami U, Earle KM |title=Craniopharyngiomas: a clinical and pathological review |journal=Cancer |volume=37 |issue=4 |pages=1944–52 |date=April 1976 |pmid=1260697 |doi= |url=}}</ref> | ||
{| class="wikitable" | {| class="wikitable" | ||
!Type of DI | !Type of DI | ||
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* [[Lung]] involvement | * [[Lung]] involvement | ||
* [[GI bleeding]] | * [[GI bleeding]] | ||
* [[Lymphadenopathy|Lymph node enlargement]]<ref name="pmid1340034">{{cite journal| author=Ghosh KN, Bhattacharya A| title=Gonotrophic nature of Phlebotomus argentipes (Diptera: Psychodidae) in the laboratory. | journal=Rev Inst Med Trop Sao Paulo | year= 1992 | volume= 34 | issue= 2 | pages= 181-2 | pmid=1340034 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1340034 }} </ref> | * [[Lymphadenopathy|Lymph node enlargement]]<ref name="pmid1340034">{{cite journal| author=Ghosh KN, Bhattacharya A| title=Gonotrophic nature of Phlebotomus argentipes (Diptera: Psychodidae) in the laboratory. | journal=Rev Inst Med Trop Sao Paulo | year= 1992 | volume= 34 | issue= 2 | pages= 181-2 | pmid=1340034 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1340034 }} </ref> | ||
| | | | ||
* CD1a and CD45 + | * CD1a and CD45 + | ||
Revision as of 18:05, 7 February 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Marjan Khan M.B.B.S.[2]
Overview
Craniopharyngioma must be differentiated from other pituitary masses such as sarcoid, pituitary adenoma, aneurysm, teratoma, tuberculosis, rathke cleft cyst, chordoma, hypothalamic glioma, hamartoma of tuber cinereum, histiocytosis, meningioma and optic nerve glioma.
Differentiating Craniopharyngioma from other Diseases
Craniopharyngioma is a mass in the pituitary region. The common pituitary masses that can be confused with craniopharyngioma are following.[1] [2] [2]
| Type of DI | Subclass | Disease | Defining signs and symptoms | Lab/Imaging findings |
|---|---|---|---|---|
| Central | Acquired | Histiocytosis |
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| Craniopharyngioma |
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 | ||
| Sarcoidosis |
|
 | ||
| Congenital | Hydrocephalus |
|
Dilated ventricles on CT and MRI
 | |
| Wolfram Syndrome (DIDMOAD) |
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| Nephrogenic | Acquired | Drug-induced (demeclocycline, lithium) |
| |
| Hypercalcemia |
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| Hypokalemia |
| |||
| Multiple myeloma |
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 | ||
| Sickle cell disease |
|
 | ||
| Primary polydipsia | Psychogenic |
| ||
| Gestational diabetes insipidus |
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| Diabetes mellitus |
| |||
References
- ↑ Petito CK, DeGirolami U, Earle KM (April 1976). "Craniopharyngiomas: a clinical and pathological review". Cancer. 37 (4): 1944–52. PMID 1260697.
- ↑ 2.0 2.1 Bunin GR, Surawicz TS, Witman PA, Preston-Martin S, Davis F, Bruner JM (October 1998). "The descriptive epidemiology of craniopharyngioma". J. Neurosurg. 89 (4): 547–51. doi:10.3171/jns.1998.89.4.0547. PMID 9761047.</re
- Sarcoid, sellar tumour (pituitary adenoma)
- Aneurysm
- Teratoma or tuberculosis (and other granulomatous diseases)
- Cleft cyst (Rathke), chordoma
- Hypothalamic glioma, hamartoma of tuber cinereum, histiocytosis
- Meningioma, metastasis
- Optic nerve glioma
- ↑ Ghosh KN, Bhattacharya A (1992). "Gonotrophic nature of Phlebotomus argentipes (Diptera: Psychodidae) in the laboratory". Rev Inst Med Trop Sao Paulo. 34 (2): 181–2. PMID 1340034.