Epithelial ovarian tumors classification: Difference between revisions
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==Classification== | ==Classification== | ||
=== General Classification === | |||
* '''Epithelial ovarian tumors''' can broadly be classified on the bases of histopathology and clinical behavior as: | * '''Epithelial ovarian tumors''' can broadly be classified on the bases of histopathology and clinical behavior as: | ||
** Benign | ** Benign | ||
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* '''Transitional cell tumors''' | * '''Transitional cell tumors''' | ||
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=== WHO Classification of Ovarian Epithelial Tumors === | |||
* '''WHO''' classifies epithelial ovarian tumors on the basis of histology as follows: | * '''WHO''' classifies epithelial ovarian tumors on the basis of histology as follows: | ||
** '''Serous tumors:''' | ** '''Serous tumors:''' | ||
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*** Adenosarcoma | *** Adenosarcoma | ||
*** Carcinosarcoma (formerly mixed Müllerian tumors) | *** Carcinosarcoma (formerly mixed Müllerian tumors) | ||
=== Epithelial Ovarian Cancer Classification Based on Clinicopathologic and Molecular Evidence === | |||
* Recent advances in histopathology and a better understanding of clinicopathologic characteristics have led to a classification system that correlates histology and clinical characteristics; | |||
* This classification subdivides malignant ovarian tumors in two types. | |||
* '''Type I''' tumors generally arise from endometriosis or fallopian tubal related serous epithelium. They exhibit less aggressive clinical course and a different genetic profile relative to '''Type II'''. | |||
* '''Type II''' tumors generally arise from fallopian tubal epithelium. They exhibit more aggressive clinical course and a different genetic profile relative to '''Type I'''. | |||
** | ** | ||
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==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 16:45, 13 February 2019
Template:Eithelial Ovarian Cancers
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Hannan Javed, M.D.[2]
Overview
Classification
General Classification
- Epithelial ovarian tumors can broadly be classified on the bases of histopathology and clinical behavior as:
- Benign
- Borderline
- Malignant tumors
- Table below provides a summary of this classification:
| Epithelial ovarian tumors | ||
|---|---|---|
| Benign | Borderline | Malignant |
|
|
|
WHO Classification of Ovarian Epithelial Tumors
- WHO classifies epithelial ovarian tumors on the basis of histology as follows:
- Serous tumors:
- Benign (cystadenoma)
- Borderline tumors (serous borderline tumor)
- Malignant (serous adenocarcinoma)
- Mucinous tumors:
- Benign (cystadenoma)
- Borderline tumors (mucinous borderline tumor)
- Malignant (mucinous adenocarcinoma)
- Endometrioid tumors:
- Benign (cystadenoma)
- Borderline tumors (endometrioid borderline tumor)
- Malignant (endometrioid adenocarcinoma)
- Clear cell tumors:
- Benign
- Borderline tumors
- Malignant (clear cell adenocarcinoma)
- Transitional cell tumors:
- Brenner tumor
- Brenner tumor of borderline malignancy
- Malignant Brenner tumor
- Transitional cell carcinoma (non-Brenner type)
- Epithelial-stromal:
- Adenosarcoma
- Carcinosarcoma (formerly mixed Müllerian tumors)
- Serous tumors:
Epithelial Ovarian Cancer Classification Based on Clinicopathologic and Molecular Evidence
- Recent advances in histopathology and a better understanding of clinicopathologic characteristics have led to a classification system that correlates histology and clinical characteristics;
- This classification subdivides malignant ovarian tumors in two types.
- Type I tumors generally arise from endometriosis or fallopian tubal related serous epithelium. They exhibit less aggressive clinical course and a different genetic profile relative to Type II.
- Type II tumors generally arise from fallopian tubal epithelium. They exhibit more aggressive clinical course and a different genetic profile relative to Type I.
| Epithelial Ovarian Cancer | |
|---|---|
| Type I | Type II |
|
|
| Ovarian Cancer | |||
|---|---|---|---|
| Epithelial | Sex-cord stromal | Germ cell | Mixed-cell type |
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