Thymoma diagnostic study of choice: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Thymoma}} | {{Thymoma}} | ||
{{CMG}} {{AE}} [[User:K.Nouman|Khuram Nouman, M.D. [2]]] | {{CMG}} {{shyam}} {{AE}} [[User:K.Nouman|Khuram Nouman, M.D. [2]]] | ||
== Overview == | == Overview == | ||
Thymoma can be largely diagnosed by using radiological techniques. | Thymoma can be largely diagnosed by using radiological techniques. | ||
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* Among the patients who present with clinical signs of [[myasthenia gravis]] (MG), the [[Computed tomography|CT Scan]] is the test of choice for the diagnosis of Thymoma. | * Among the patients who present with clinical signs of [[myasthenia gravis]] (MG), the [[Computed tomography|CT Scan]] is the test of choice for the diagnosis of Thymoma. | ||
* [[Computed tomography|CT Scan]] with IV contrast and magnetic resonance imaging are helpful in determining the vascularity of the thymoma and helps in safe surgical removal of large tumors. | * [[Computed tomography|CT Scan]] with IV contrast and magnetic resonance imaging are helpful in determining the vascularity of the thymoma and helps in safe surgical removal of large tumors. | ||
* PET | * PET scan is very valuable in diagnosing the cases of invasive [[malignant]] thymoma.<ref name="pmid26273398">{{cite journal| author=Scagliori E, Evangelista L, Panunzio A, Calabrese F, Nannini N, Polverosi R et al.| title=Conflicting or complementary role of computed tomography (CT) and positron emission tomography (PET)/CT in the assessment of thymic cancer and thymoma: our experience and literature review. | journal=Thorac Cancer | year= 2015 | volume= 6 | issue= 4 | pages= 433-42 | pmid=26273398 | doi=10.1111/1759-7714.12197 | pmc=4511321 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26273398 }} </ref> | ||
* Thallium 201 single photon emission computed tomography is useful to distinguish normal thymic tissue from hyperplastic tissue or thymoma | * Thallium 201 single photon emission computed tomography is useful to distinguish normal thymic tissue from hyperplastic tissue or thymoma | ||
* Ultrasonically guided core needle biopsy is used to obtain larger tissue specimens for histological examination. Annessi and colleagues were able to diagnose thymoma in all patients that had undergone anterior mediastinal core [[needle biopsy]] by ultrasonic guidance with a [[sensitivity]] and [[specificity]] of 100%. | * Ultrasonically guided core needle biopsy is used to obtain larger tissue specimens for histological examination. Annessi and colleagues were able to diagnose thymoma in all patients that had undergone anterior mediastinal core [[needle biopsy]] by ultrasonic guidance with a [[sensitivity]] and [[specificity]] of 100%. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2] Associate Editor(s)-in-Chief: Khuram Nouman, M.D. [2]
Overview
Thymoma can be largely diagnosed by using radiological techniques.
Diagnostic Study of Choice
Investigations:
- Posterior-anterior (PA) and lateral X-ray of the chest are helpful in diagnosing most of thymomas.
- Among the patients who present with clinical signs of myasthenia gravis (MG), the CT Scan is the test of choice for the diagnosis of Thymoma.
- CT Scan with IV contrast and magnetic resonance imaging are helpful in determining the vascularity of the thymoma and helps in safe surgical removal of large tumors.
- PET scan is very valuable in diagnosing the cases of invasive malignant thymoma.[1]
- Thallium 201 single photon emission computed tomography is useful to distinguish normal thymic tissue from hyperplastic tissue or thymoma
- Ultrasonically guided core needle biopsy is used to obtain larger tissue specimens for histological examination. Annessi and colleagues were able to diagnose thymoma in all patients that had undergone anterior mediastinal core needle biopsy by ultrasonic guidance with a sensitivity and specificity of 100%.
References
- ↑ Scagliori E, Evangelista L, Panunzio A, Calabrese F, Nannini N, Polverosi R; et al. (2015). "Conflicting or complementary role of computed tomography (CT) and positron emission tomography (PET)/CT in the assessment of thymic cancer and thymoma: our experience and literature review". Thorac Cancer. 6 (4): 433–42. doi:10.1111/1759-7714.12197. PMC 4511321. PMID 26273398.