Gonadoblastoma history and symptoms: Difference between revisions
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===History=== | ===History=== | ||
Patients with gonadoblastoma may have a positive history of:<ref name="978-0-323-40067-1">{{cite book | last = Saia | first = Philip | title = Clinical gynecologic oncology | publisher = Elsevier | location = Philadelphia, PA | year = 2018 | isbn = 978-0-323-40067-1 }}</ref><ref name="pmid2231948">{{cite journal |vauthors=Chapman WH, Plymyer MR, Dresner ML |title=Gonadoblastoma in an anatomically normal man: a case report and literature review |journal=J. Urol. |volume=144 |issue=6 |pages=1472–4 |date=December 1990 |pmid=2231948 |doi= |url=}}</ref> | Patients with gonadoblastoma may have a positive history of:<ref name="978-0-323-40067-1">{{cite book | last = Saia | first = Philip | title = Clinical gynecologic oncology | publisher = Elsevier | location = Philadelphia, PA | year = 2018 | isbn = 978-0-323-40067-1 }}</ref><ref name="pmid2231948">{{cite journal |vauthors=Chapman WH, Plymyer MR, Dresner ML |title=Gonadoblastoma in an anatomically normal man: a case report and literature review |journal=J. Urol. |volume=144 |issue=6 |pages=1472–4 |date=December 1990 |pmid=2231948 |doi= |url=}}</ref> | ||
*[[Ambiguous genitalia]] | * [[Ambiguous genitalia]] | ||
*Sexual development disorders | * Sexual development disorders | ||
*[[Hypospadias]] or [[undescended testes]] | * [[Hypospadias]] or [[undescended testes]] | ||
===Common Symptoms=== | ===Common Symptoms=== | ||
Common symptoms of gonadoblastoma include:<ref name="978-0-323-40067-1">{{cite book | last = Saia | first = Philip | title = Clinical gynecologic oncology | publisher = Elsevier | location = Philadelphia, PA | year = 2018 | isbn = 978-0-323-40067-1 }}</ref><ref name="pmid2231948">{{cite journal |vauthors=Chapman WH, Plymyer MR, Dresner ML |title=Gonadoblastoma in an anatomically normal man: a case report and literature review |journal=J. Urol. |volume=144 |issue=6 |pages=1472–4 |date=December 1990 |pmid=2231948 |doi= |url=}}</ref> | Common symptoms of gonadoblastoma include:<ref name="978-0-323-40067-1">{{cite book | last = Saia | first = Philip | title = Clinical gynecologic oncology | publisher = Elsevier | location = Philadelphia, PA | year = 2018 | isbn = 978-0-323-40067-1 }}</ref><ref name="pmid2231948">{{cite journal |vauthors=Chapman WH, Plymyer MR, Dresner ML |title=Gonadoblastoma in an anatomically normal man: a case report and literature review |journal=J. Urol. |volume=144 |issue=6 |pages=1472–4 |date=December 1990 |pmid=2231948 |doi= |url=}}</ref> | ||
*[[Primary amenorrhea]] | * [[Primary amenorrhea]] | ||
*[[Virilization]] | * [[Virilization]] | ||
===Less Common Symptoms=== | ===Less Common Symptoms=== | ||
Less common symptoms of gonadoblastoma include:<ref name="978-0-323-40067-1">{{cite book | last = Saia | first = Philip | title = Clinical gynecologic oncology | publisher = Elsevier | location = Philadelphia, PA | year = 2018 | isbn = 978-0-323-40067-1 }}</ref><ref name="pmid2231948">{{cite journal |vauthors=Chapman WH, Plymyer MR, Dresner ML |title=Gonadoblastoma in an anatomically normal man: a case report and literature review |journal=J. Urol. |volume=144 |issue=6 |pages=1472–4 |date=December 1990 |pmid=2231948 |doi= |url=}}</ref> | Less common symptoms of gonadoblastoma include:<ref name="978-0-323-40067-1">{{cite book | last = Saia | first = Philip | title = Clinical gynecologic oncology | publisher = Elsevier | location = Philadelphia, PA | year = 2018 | isbn = 978-0-323-40067-1 }}</ref><ref name="pmid2231948">{{cite journal |vauthors=Chapman WH, Plymyer MR, Dresner ML |title=Gonadoblastoma in an anatomically normal man: a case report and literature review |journal=J. Urol. |volume=144 |issue=6 |pages=1472–4 |date=December 1990 |pmid=2231948 |doi= |url=}}</ref> | ||
*Growing [[mass]] in [[testicles]] | * Growing [[mass]] in [[testicles]] | ||
*Chronic pain in testis | * Chronic pain in testis | ||
*Low [[abdominal mass]] in phenotypically normal women | * Low [[abdominal mass]] in phenotypically normal women | ||
==References== | ==References== | ||
Revision as of 21:36, 19 February 2019
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Gonadoblastoma Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
Patients with gonadoblastoma present either during infancy with ambiguous genitalia or later with sexual developmental complaints. The hallmark of gonadoblastoma is gonadal developmental disorders. The majority of affected individuals are phenotypically women and may be discovered during a workup for virilization and/or primary amenorrhea. Others are phenotypically men with sex organs developmental problems such as cryptorchidism and hypospadias.Although very rarely, gonadoblastoma has been found in anatomically normal male individuals. In these individuals, it may present with a sense of discomfort or pain in testicles.
History and Symptoms
History
Patients with gonadoblastoma may have a positive history of:[1][2]
- Ambiguous genitalia
- Sexual development disorders
- Hypospadias or undescended testes
Common Symptoms
Common symptoms of gonadoblastoma include:[1][2]
Less Common Symptoms
Less common symptoms of gonadoblastoma include:[1][2]
- Growing mass in testicles
- Chronic pain in testis
- Low abdominal mass in phenotypically normal women
References
- ↑ 1.0 1.1 1.2 Saia, Philip (2018). Clinical gynecologic oncology. Philadelphia, PA: Elsevier. ISBN 978-0-323-40067-1.
- ↑ 2.0 2.1 2.2 Chapman WH, Plymyer MR, Dresner ML (December 1990). "Gonadoblastoma in an anatomically normal man: a case report and literature review". J. Urol. 144 (6): 1472–4. PMID 2231948.