Ovarian germ cell tumor history and symptoms: Difference between revisions
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** Acute abdominal pain may indicate the tumor is complicated by ovarian torsion or rupture that may happen in 5%-10% and 1%-3% of affected individuals, respectively. | ** Acute abdominal pain may indicate the tumor is complicated by ovarian torsion or rupture that may happen in 5%-10% and 1%-3% of affected individuals, respectively. | ||
*** Torsion usually tends to complicate at a greater extent the intermediate-sized tumors rather than the larger or smaller ones. | *** Torsion usually tends to complicate at a greater extent the intermediate-sized tumors rather than the larger or smaller ones. | ||
* Very rarely, mature teratoma can manifest with neurologic symptoms due to associated Anti-NMDA receptor encephalitis. Symptoms such as:<ref name="DalmauGleichman2008">{{cite journal|last1=Dalmau|first1=Josep|last2=Gleichman|first2=Amy J|last3=Hughes|first3=Ethan G|last4=Rossi|first4=Jeffrey E|last5=Peng|first5=Xiaoyu|last6=Lai|first6=Meizan|last7=Dessain|first7=Scott K|last8=Rosenfeld|first8=Myrna R|last9=Balice-Gordon|first9=Rita|last10=Lynch|first10=David R|title=Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies|journal=The Lancet Neurology|volume=7|issue=12|year=2008|pages=1091–1098|issn=14744422|doi=10.1016/S1474-4422(08)70224-2}}</ref> | |||
** Memory problems | |||
** Psychiatric problems | |||
** Decreased level of consciousness | |||
** Seizure | |||
** Dyskinesia | |||
==References== | ==References== | ||
Revision as of 21:11, 26 February 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
The clinical manifestations of patients with ovarian germ cell tumors depend on the type of the tumor and its potential to produce hormonal materials. Usually, they present with abdominal pain or distention, menstrual irregularities, symptoms of virilization, rapidly growing abdominal/pelvic mass, acute abdominal pain from complications such as necrosis, capsular distention, rupture or torsion and or simply they can be asymptomatic.
History and Symptoms
The clinical manifestations of patients with ovarian germ cell tumors depend on the type of the tumor and its potential to produce hormonal materials. Usually, they present with abdominal pain or distention, menstrual irregularities, symptoms of virilization, rapidly growing abdominal/pelvic mass, acute abdominal pain from complications such as necrosis, capsular distention, rupture or torsion and or simply they can be asymptomatic.[1]
Mature teratoma
- Approximately 20 % of patients with mature ovarian teratoma are asymptomatic.[2]
- The most common symptom in those who are symptomatic is lower abdominal pain.
- Acute abdominal pain may indicate the tumor is complicated by ovarian torsion or rupture that may happen in 5%-10% and 1%-3% of affected individuals, respectively.
- Torsion usually tends to complicate at a greater extent the intermediate-sized tumors rather than the larger or smaller ones.
- Acute abdominal pain may indicate the tumor is complicated by ovarian torsion or rupture that may happen in 5%-10% and 1%-3% of affected individuals, respectively.
- Very rarely, mature teratoma can manifest with neurologic symptoms due to associated Anti-NMDA receptor encephalitis. Symptoms such as:[3]
- Memory problems
- Psychiatric problems
- Decreased level of consciousness
- Seizure
- Dyskinesia
References
- ↑ Low, Jeffrey J.H.; Ilancheran, Arunachalam; Ng, Joseph S. (2012). "Malignant ovarian germ-cell tumours". Best Practice & Research Clinical Obstetrics & Gynaecology. 26 (3): 347–355. doi:10.1016/j.bpobgyn.2012.01.002. ISSN 1521-6934.
- ↑ Ayhan, Ali; Bukulmez, Orhan; Genc, Cuneyt; Karamursel, Burcu S.; Ayhan, Ayse (2000). "Mature cystic teratomas of the ovary: case series from one institution over 34 years". European Journal of Obstetrics & Gynecology and Reproductive Biology. 88 (2): 153–157. doi:10.1016/S0301-2115(99)00141-4. ISSN 0301-2115.
- ↑ Dalmau, Josep; Gleichman, Amy J; Hughes, Ethan G; Rossi, Jeffrey E; Peng, Xiaoyu; Lai, Meizan; Dessain, Scott K; Rosenfeld, Myrna R; Balice-Gordon, Rita; Lynch, David R (2008). "Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies". The Lancet Neurology. 7 (12): 1091–1098. doi:10.1016/S1474-4422(08)70224-2. ISSN 1474-4422.