Desmoid tumor other diagnostic studies: Difference between revisions

	Desmoid tumor Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Desmoid tumor from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
CT
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1

Revision as of 20:01, 1 March 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]

Antibodies including smooth muscle actin, desmin and KIT are often examined to aid in distinguishing desmoids from other tumors.

Characteristic features of desmoid tumors on immunohistochemistry and relevant antibodies
Other diagnostic tests	Associated characteristics features
Immunohistochemistry (aids histologic diagnosis)	Spindle cells on immunohistochemical stains show the following features: Positive for: Nuclear beta-catenin (regardless of the site, 90% of desmoids show nuclear reactivity, relatively high specificity) Vimentin Smooth muscle actin Negative for: Desmin Cytokeratins S-100
Antibodies	In order to distinguish desmoid tumors from other tumors, following antibodies are often examined: Smooth muscle actin Desmin KIT

@@ Line 12: / Line 12: @@
 !Associated characteristics features
 |-
-|Immunohistochemistry
+|'''Immunohistochemistry'''
 (aids histologic diagnosis)
 |Spindle cells on immunohistochemical stains show the following features:
@@ Line 24: / Line 24: @@
 **S-100
 |-
-|Antibodies
+|'''Antibodies'''
 |In order to distinguish desmoid tumors from other tumors, following antibodies are often examined:
 *Smooth muscle actin