Ovarian germ cell tumor classification: Difference between revisions
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*Yolk sac tumor | *Yolk sac tumor | ||
*Mixed germ cell tumors | *Mixed germ cell tumors | ||
*Pure embryonal carcinoma | |||
*Non-gestational choriocarcinoma | |||
*Pure embryoma | |||
=== WHO Classification of Ovarian Tumors === | === WHO Classification of Ovarian Tumors === | ||
'''WHO''' classifies ovarian tumors as follows:<ref name="pmid27983698">{{cite journal |vauthors=Rojas V, Hirshfield KM, Ganesan S, Rodriguez-Rodriguez L |title=Molecular Characterization of Epithelial Ovarian Cancer: Implications for Diagnosis and Treatment |journal=Int J Mol Sci |volume=17 |issue=12 |pages= |date=December 2016 |pmid=27983698 |pmc=5187913 |doi=10.3390/ijms17122113 |url=}}</ref><ref name="pmid26054417">{{cite journal |vauthors=Horta M, Cunha TM |title=Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists |journal=Diagn Interv Radiol |volume=21 |issue=4 |pages=277–86 |date=2015 |pmid=26054417 |pmc=4498422 |doi=10.5152/dir.2015.34414 |url=}}</ref><ref name="pmid21716157">{{cite journal |vauthors=McCluggage WG |title=Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis |journal=Pathology |volume=43 |issue=5 |pages=420–32 |date=August 2011 |pmid=21716157 |doi=10.1097/PAT.0b013e328348a6e7 |url=}}</ref><ref name="pmid26894303">{{cite journal |vauthors=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J |title=The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications |journal=Arch. Gynecol. Obstet. |volume=293 |issue=4 |pages=695–700 |date=April 2016 |pmid=26894303 |doi=10.1007/s00404-016-4035-8 |url=}}</ref><ref name="urlonlinelibrary.wiley.com">{{cite web |url=https://onlinelibrary.wiley.com/doi/pdf/10.1002/cncr.11345 |title=onlinelibrary.wiley.com |format= |work= |accessdate=}}</ref><ref name="pmid20154587">{{cite journal |vauthors=Kurman RJ, Shih IeM |title=The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory |journal=Am. J. Surg. Pathol. |volume=34 |issue=3 |pages=433–43 |date=March 2010 |pmid=20154587 |pmc=2841791 |doi=10.1097/PAS.0b013e3181cf3d79 |url=}}</ref> | '''WHO''' classifies ovarian tumors as follows:<ref name="pmid27983698">{{cite journal |vauthors=Rojas V, Hirshfield KM, Ganesan S, Rodriguez-Rodriguez L |title=Molecular Characterization of Epithelial Ovarian Cancer: Implications for Diagnosis and Treatment |journal=Int J Mol Sci |volume=17 |issue=12 |pages= |date=December 2016 |pmid=27983698 |pmc=5187913 |doi=10.3390/ijms17122113 |url=}}</ref><ref name="pmid26054417">{{cite journal |vauthors=Horta M, Cunha TM |title=Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists |journal=Diagn Interv Radiol |volume=21 |issue=4 |pages=277–86 |date=2015 |pmid=26054417 |pmc=4498422 |doi=10.5152/dir.2015.34414 |url=}}</ref><ref name="pmid21716157">{{cite journal |vauthors=McCluggage WG |title=Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis |journal=Pathology |volume=43 |issue=5 |pages=420–32 |date=August 2011 |pmid=21716157 |doi=10.1097/PAT.0b013e328348a6e7 |url=}}</ref><ref name="pmid26894303">{{cite journal |vauthors=Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J |title=The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications |journal=Arch. Gynecol. Obstet. |volume=293 |issue=4 |pages=695–700 |date=April 2016 |pmid=26894303 |doi=10.1007/s00404-016-4035-8 |url=}}</ref><ref name="urlonlinelibrary.wiley.com">{{cite web |url=https://onlinelibrary.wiley.com/doi/pdf/10.1002/cncr.11345 |title=onlinelibrary.wiley.com |format= |work= |accessdate=}}</ref><ref name="pmid20154587">{{cite journal |vauthors=Kurman RJ, Shih IeM |title=The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory |journal=Am. J. Surg. Pathol. |volume=34 |issue=3 |pages=433–43 |date=March 2010 |pmid=20154587 |pmc=2841791 |doi=10.1097/PAS.0b013e3181cf3d79 |url=}}</ref> | ||
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* '''Tumor-like lesions''' | * '''Tumor-like lesions''' | ||
|} | |} | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 15:14, 7 March 2019
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Ovarian germ cell tumor Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
Ovarian germ cell tumor may be benign or malignant. Each category subclassified to different types based on histologic features.
Classification
Ovarian germ cell tumor may be classified into two subtypes of benign and malignant tumors. Benign tumors are comprised of only teratoma, however, the malignant germ cell tumors may be classified to different types according to the histologic features.
- Teratoma[1]
- Mature cystic teratomas (dermoid cysts)
- Immature teratomas
- Monodermal teratomas
- Struma ovarii
- Carcinoid tumors
- Neural tumors
- Dysgerminoma
- Yolk sac tumor
- Mixed germ cell tumors
- Pure embryonal carcinoma
- Non-gestational choriocarcinoma
- Pure embryoma
WHO Classification of Ovarian Tumors
WHO classifies ovarian tumors as follows:[2][3][4][5][6][7]
| Ovarian Cancer | |||
|---|---|---|---|
| Epithelial | Sex-cord stromal | Germ cell | Others |
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References
- ↑ Outwater EK, Siegelman ES, Hunt JL (2001). "Ovarian teratomas: tumor types and imaging characteristics". Radiographics. 21 (2): 475–90. doi:10.1148/radiographics.21.2.g01mr09475. PMID 11259710.
- ↑ Rojas V, Hirshfield KM, Ganesan S, Rodriguez-Rodriguez L (December 2016). "Molecular Characterization of Epithelial Ovarian Cancer: Implications for Diagnosis and Treatment". Int J Mol Sci. 17 (12). doi:10.3390/ijms17122113. PMC 5187913. PMID 27983698.
- ↑ Horta M, Cunha TM (2015). "Sex cord-stromal tumors of the ovary: a comprehensive review and update for radiologists". Diagn Interv Radiol. 21 (4): 277–86. doi:10.5152/dir.2015.34414. PMC 4498422. PMID 26054417.
- ↑ McCluggage WG (August 2011). "Morphological subtypes of ovarian carcinoma: a review with emphasis on new developments and pathogenesis". Pathology. 43 (5): 420–32. doi:10.1097/PAT.0b013e328348a6e7. PMID 21716157.
- ↑ Meinhold-Heerlein I, Fotopoulou C, Harter P, Kurzeder C, Mustea A, Wimberger P, Hauptmann S, Sehouli J (April 2016). "The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications". Arch. Gynecol. Obstet. 293 (4): 695–700. doi:10.1007/s00404-016-4035-8. PMID 26894303.
- ↑ "onlinelibrary.wiley.com".
- ↑ Kurman RJ, Shih I (March 2010). "The origin and pathogenesis of epithelial ovarian cancer: a proposed unifying theory". Am. J. Surg. Pathol. 34 (3): 433–43. doi:10.1097/PAS.0b013e3181cf3d79. PMC 2841791. PMID 20154587. Vancouver style error: initials (help)