Ovarian germ cell tumor risk factors: Difference between revisions
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==Overview== | ==Overview== | ||
[[Gonadal dysgeneisis]] and androgen insensitivity syndrome are known risk factors for the development of [[ovarian]] [[germ cell]] [[tumors]]. | |||
==Risk Factors== | ==Risk Factors== | ||
[[Ovarian]] [[germ cell]] [[tumors]] tend to affect individuals with [[gonadal dysgenesis]] at a greater extent.<ref name="PleskacovaHersmus2010">{{cite journal|last1=Pleskacova|first1=J.|last2=Hersmus|first2=R.|last3=Oosterhuis|first3=J.W.|last4=Setyawati|first4=B.A.|last5=Faradz|first5=S.M.|last6=Cools|first6=M.|last7=Wolffenbuttel|first7=K.P.|last8=Lebl|first8=J.|last9=Drop|first9=S.L.|last10=Looijenga|first10=L.H.|title=Tumor Risk in Disorders of Sex Development|journal=Sexual Development|volume=4|issue=4-5|year=2010|pages=259–269|issn=1661-5433|doi=10.1159/000314536}}</ref> | |||
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===Mature teratoma=== | ===Mature teratoma=== | ||
*Common risk factors in the malignant transformation of mature teratoma include: | *Common risk factors in the malignant transformation of mature teratoma include: | ||
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===Dysgerminoma=== | ===Dysgerminoma=== | ||
*Common risk factors in the development of dysgerminoma are [[gonadal dysgenesis]], [[androgen insensitivity syndrome]] and [[gonadoblastoma]].<ref name= wqd>{{cite book | last = Kliegman | first = Robert | title = Nelson textbook of pediatrics | publisher = Elsevier/Saunders | location = Philadelphia, PA | year = 2011 | isbn = 978-1-4377-0755-7 }}</ref> | *Common risk factors in the development of dysgerminoma are [[gonadal dysgenesis]], [[androgen insensitivity syndrome]] and [[gonadoblastoma]].<ref name= wqd>{{cite book | last = Kliegman | first = Robert | title = Nelson textbook of pediatrics | publisher = Elsevier/Saunders | location = Philadelphia, PA | year = 2011 | isbn = 978-1-4377-0755-7 }}</ref> | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 18:36, 15 March 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2] Monalisa Dmello, M.B,B.S., M.D. [3]
Overview
Gonadal dysgeneisis and androgen insensitivity syndrome are known risk factors for the development of ovarian germ cell tumors.
Risk Factors
Ovarian germ cell tumors tend to affect individuals with gonadal dysgenesis at a greater extent.[1]
Mature teratoma
- Common risk factors in the malignant transformation of mature teratoma include:
Dysgerminoma
- Common risk factors in the development of dysgerminoma are gonadal dysgenesis, androgen insensitivity syndrome and gonadoblastoma.[4]
References
- ↑ Pleskacova, J.; Hersmus, R.; Oosterhuis, J.W.; Setyawati, B.A.; Faradz, S.M.; Cools, M.; Wolffenbuttel, K.P.; Lebl, J.; Drop, S.L.; Looijenga, L.H. (2010). "Tumor Risk in Disorders of Sex Development". Sexual Development. 4 (4–5): 259–269. doi:10.1159/000314536. ISSN 1661-5433.
- ↑ Hackethal A, Brueggmann D, Bohlmann MK, Franke FE, Tinneberg HR, Münstedt K (December 2008). "Squamous-cell carcinoma in mature cystic teratoma of the ovary: systematic review and analysis of published data". Lancet Oncol. 9 (12): 1173–80. doi:10.1016/S1470-2045(08)70306-1. PMID 19038764.
- ↑ Park, Jeong-Yeol; Kim, Dae-Yeon; Kim, Jong-Hyeok; Kim, Yong-Man; Kim, Young-Tak; Nam, Joo-Hyun (2008). "Malignant transformation of mature cystic teratoma of the ovary: Experience at a single institution". European Journal of Obstetrics & Gynecology and Reproductive Biology. 141 (2): 173–178. doi:10.1016/j.ejogrb.2008.07.032. ISSN 0301-2115.
- ↑ Kliegman, Robert (2011). Nelson textbook of pediatrics. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1-4377-0755-7.