Nasopharyngeal carcinoma interventions: Difference between revisions

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==Overview==
==Overview==
==Indications==
'''<big>Radiotherapy:</big>'''
'''<big>Radiotherapy:</big>'''


'''Stage I and II:'''
'''Stage I and II:'''<ref name="LeeNg2014">{{cite journal|last1=Lee|first1=Anne W.M.|last2=Ng|first2=Wai Tong|last3=Chan|first3=Lucy L.K.|last4=Hung|first4=Wai Man|last5=Chan|first5=Connie C.C.|last6=Sze|first6=Henry C.K.|last7=Chan|first7=Oscar S.H.|last8=Chang|first8=Amy T.Y.|last9=Yeung|first9=Rebecca M.W.|title=Evolution of treatment for nasopharyngeal cancer – Success and setback in the intensity-modulated radiotherapy era|journal=Radiotherapy and Oncology|volume=110|issue=3|year=2014|pages=377–384|issn=01678140|doi=10.1016/j.radonc.2014.02.003}}</ref>
* The mainstay of treatment for early stages of nasopharyngeal carcinoma is radiotherapy.  
* The mainstay of treatment for early stages of nasopharyngeal carcinoma is radiotherapy.  
* Place of radiation:
* Place of radiation:
** both sides of neck
** both sides of the neck
** retropharyngeal nodes
** retropharyngeal nodes
* Dose:
* Dose:
** Primary tumor and affected lymph nodes: 66–70 Gy
** Primary tumor and affected lymph nodes: 66–70 Gy
** Uninvolved neck: 50 Gy
** Uninvolved neck: 50 Gy
 
'''Stage III and IV:'''<ref name="Ribassin-MajedMarguet2017">{{cite journal|last1=Ribassin-Majed|first1=Laureen|last2=Marguet|first2=Sophie|last3=Lee|first3=Anne W.M.|last4=Ng|first4=Wai Tong|last5=Ma|first5=Jun|last6=Chan|first6=Anthony T.C.|last7=Huang|first7=Pei-Yu|last8=Zhu|first8=Guopei|last9=Chua|first9=Daniel T.T.|last10=Chen|first10=Yong|last11=Mai|first11=Hai-Qiang|last12=Kwong|first12=Dora L.W.|last13=Cheah|first13=Shie-Lee|last14=Moon|first14=James|last15=Tung|first15=Yuk|last16=Chi|first16=Kwan-Hwa|last17=Fountzilas|first17=George|last18=Bourhis|first18=Jean|last19=Pignon|first19=Jean Pierre|last20=Blanchard|first20=Pierre|title=What Is the Best Treatment of Locally Advanced Nasopharyngeal Carcinoma? An Individual Patient Data Network Meta-Analysis|journal=Journal of Clinical Oncology|volume=35|issue=5|year=2017|pages=498–505|issn=0732-183X|doi=10.1200/JCO.2016.67.4119}}</ref>
==Indications==
* In these patients radiotherapy is used in combination with chemotherapy.
 
The mainstay of treatment for TT is medical therapy.


==References==
==References==

Revision as of 14:41, 19 March 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief:

Overview

Indications

Radiotherapy:

Stage I and II:[1]

  • The mainstay of treatment for early stages of nasopharyngeal carcinoma is radiotherapy.
  • Place of radiation:
    • both sides of the neck
    • retropharyngeal nodes
  • Dose:
    • Primary tumor and affected lymph nodes: 66–70 Gy
    • Uninvolved neck: 50 Gy

Stage III and IV:[2]

  • In these patients radiotherapy is used in combination with chemotherapy.

References

  1. Lee, Anne W.M.; Ng, Wai Tong; Chan, Lucy L.K.; Hung, Wai Man; Chan, Connie C.C.; Sze, Henry C.K.; Chan, Oscar S.H.; Chang, Amy T.Y.; Yeung, Rebecca M.W. (2014). "Evolution of treatment for nasopharyngeal cancer – Success and setback in the intensity-modulated radiotherapy era". Radiotherapy and Oncology. 110 (3): 377–384. doi:10.1016/j.radonc.2014.02.003. ISSN 0167-8140.
  2. Ribassin-Majed, Laureen; Marguet, Sophie; Lee, Anne W.M.; Ng, Wai Tong; Ma, Jun; Chan, Anthony T.C.; Huang, Pei-Yu; Zhu, Guopei; Chua, Daniel T.T.; Chen, Yong; Mai, Hai-Qiang; Kwong, Dora L.W.; Cheah, Shie-Lee; Moon, James; Tung, Yuk; Chi, Kwan-Hwa; Fountzilas, George; Bourhis, Jean; Pignon, Jean Pierre; Blanchard, Pierre (2017). "What Is the Best Treatment of Locally Advanced Nasopharyngeal Carcinoma? An Individual Patient Data Network Meta-Analysis". Journal of Clinical Oncology. 35 (5): 498–505. doi:10.1200/JCO.2016.67.4119. ISSN 0732-183X.

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