Epithelial ovarian tumors history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
The [[clinical]] manifestations of patients with | The [[clinical]] manifestations of patients with epithelial ovarian tumors depend on the type of the [[tumor]] and its potential to produce [[hormonal]] materials. Usually, they present with [[abdominal pain]] or [[Abdominal distention|distention]], [[menstrual irregularities]], symptoms of [[virilization]], rapidly growing [[abdominal]]/[[pelvic]] [[mass]], [[acute abdominal pain]] from [[complications]] such as [[necrosis]], [[Capsule|capsular]] distention, [[rupture]] or [[torsion]] and or simply they can be [[asymptomatic]]. | ||
==History and Symptoms== | ==History and Symptoms== | ||
The [[clinical]] manifestations of patients with | The [[clinical]] manifestations of patients with epithelial ovarian tumors depend on the type of the [[tumor]] and its potential to produce [[hormonal]] materials. Usually, they present with [[abdominal pain]] or distention, [[menstrual irregularities]], symptoms of [[virilization]], rapidly growing [[abdominal]]/[[pelvic]] [[mass]], [[acute abdominal pain]] from [[complications]] such as [[necrosis]], [[Capsule|capsular]] distention, [[rupture]] or [[torsion]] and or simply they can be [[asymptomatic]].<ref name="LowIlancheran2012">{{cite journal|last1=Low|first1=Jeffrey J.H.|last2=Ilancheran|first2=Arunachalam|last3=Ng|first3=Joseph S.|title=Malignant ovarian germ-cell tumours|journal=Best Practice & Research Clinical Obstetrics & Gynaecology|volume=26|issue=3|year=2012|pages=347–355|issn=15216934|doi=10.1016/j.bpobgyn.2012.01.002}}</ref> | ||
* Approximately 20 % of patients are [[asymptomatic]].<ref name="AyhanBukulmez2000">{{cite journal|last1=Ayhan|first1=Ali|last2=Bukulmez|first2=Orhan|last3=Genc|first3=Cuneyt|last4=Karamursel|first4=Burcu S.|last5=Ayhan|first5=Ayse|title=Mature cystic teratomas of the ovary: case series from one institution over 34 years|journal=European Journal of Obstetrics & Gynecology and Reproductive Biology|volume=88|issue=2|year=2000|pages=153–157|issn=03012115|doi=10.1016/S0301-2115(99)00141-4}}</ref> | |||
* Approximately 20 % of patients | |||
* The most common symptom in those who are [[symptomatic]] is [[lower abdominal pain]]. | * The most common symptom in those who are [[symptomatic]] is [[lower abdominal pain]]. | ||
** [[Acute abdominal pain]] may indicate the [[tumor]] is complicated by [[ovarian torsion]] or [[rupture]] that may happen in 5%-10% and 1%-3% of affected individuals, respectively. | ** [[Acute abdominal pain]] may indicate the [[tumor]] is complicated by [[ovarian torsion]] or [[rupture]] that may happen in 5%-10% and 1%-3% of affected individuals, respectively. | ||
*** [[Torsion]] usually tends to complicate at a greater extent the intermediate-sized [[tumors]] rather than the larger or smaller ones. | *** [[Torsion]] usually tends to complicate at a greater extent the intermediate-sized [[tumors]] rather than the larger or smaller ones. | ||
* Very rarely, | * Very rarely, epithelial ovarian tumors can manifest with [[neurologic]] [[symptoms]] due to associated [[Anti-NMDA receptor encephalitis]]. [[Symptoms]] such as:<ref name="DalmauGleichman2008">{{cite journal|last1=Dalmau|first1=Josep|last2=Gleichman|first2=Amy J|last3=Hughes|first3=Ethan G|last4=Rossi|first4=Jeffrey E|last5=Peng|first5=Xiaoyu|last6=Lai|first6=Meizan|last7=Dessain|first7=Scott K|last8=Rosenfeld|first8=Myrna R|last9=Balice-Gordon|first9=Rita|last10=Lynch|first10=David R|title=Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies|journal=The Lancet Neurology|volume=7|issue=12|year=2008|pages=1091–1098|issn=14744422|doi=10.1016/S1474-4422(08)70224-2}}</ref> | ||
** [[Memory]] problems | ** [[Memory]] problems | ||
** [[Psychiatric Disorders|Psychiatric]] problems | ** [[Psychiatric Disorders|Psychiatric]] problems | ||
| Line 20: | Line 19: | ||
** [[Seizure]] | ** [[Seizure]] | ||
** [[Dystonia|Dyskinesia]] | ** [[Dystonia|Dyskinesia]] | ||
=== | ===Hormonal=== | ||
*[[Menstrual irregularities]] | |||
*[[Amenorrhea]] | |||
*[[virilization]] | |||
*[[Amenorrhea]] | |||
* | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 13:51, 2 April 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hannan Javed, M.D.[2]
Overview
The clinical manifestations of patients with epithelial ovarian tumors depend on the type of the tumor and its potential to produce hormonal materials. Usually, they present with abdominal pain or distention, menstrual irregularities, symptoms of virilization, rapidly growing abdominal/pelvic mass, acute abdominal pain from complications such as necrosis, capsular distention, rupture or torsion and or simply they can be asymptomatic.
History and Symptoms
The clinical manifestations of patients with epithelial ovarian tumors depend on the type of the tumor and its potential to produce hormonal materials. Usually, they present with abdominal pain or distention, menstrual irregularities, symptoms of virilization, rapidly growing abdominal/pelvic mass, acute abdominal pain from complications such as necrosis, capsular distention, rupture or torsion and or simply they can be asymptomatic.[1]
- Approximately 20 % of patients are asymptomatic.[2]
- The most common symptom in those who are symptomatic is lower abdominal pain.
- Acute abdominal pain may indicate the tumor is complicated by ovarian torsion or rupture that may happen in 5%-10% and 1%-3% of affected individuals, respectively.
- Very rarely, epithelial ovarian tumors can manifest with neurologic symptoms due to associated Anti-NMDA receptor encephalitis. Symptoms such as:[3]
- Memory problems
- Psychiatric problems
- Decreased level of consciousness
- Seizure
- Dyskinesia
Hormonal
References
- ↑ Low, Jeffrey J.H.; Ilancheran, Arunachalam; Ng, Joseph S. (2012). "Malignant ovarian germ-cell tumours". Best Practice & Research Clinical Obstetrics & Gynaecology. 26 (3): 347–355. doi:10.1016/j.bpobgyn.2012.01.002. ISSN 1521-6934.
- ↑ Ayhan, Ali; Bukulmez, Orhan; Genc, Cuneyt; Karamursel, Burcu S.; Ayhan, Ayse (2000). "Mature cystic teratomas of the ovary: case series from one institution over 34 years". European Journal of Obstetrics & Gynecology and Reproductive Biology. 88 (2): 153–157. doi:10.1016/S0301-2115(99)00141-4. ISSN 0301-2115.
- ↑ Dalmau, Josep; Gleichman, Amy J; Hughes, Ethan G; Rossi, Jeffrey E; Peng, Xiaoyu; Lai, Meizan; Dessain, Scott K; Rosenfeld, Myrna R; Balice-Gordon, Rita; Lynch, David R (2008). "Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies". The Lancet Neurology. 7 (12): 1091–1098. doi:10.1016/S1474-4422(08)70224-2. ISSN 1474-4422.