Neurofibroma surgery: Difference between revisions
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'''Plexiform neurofibroma (NF-1 associated)''' | '''Plexiform neurofibroma (NF-1 associated)''' | ||
* The primary treatment option for [[plexiform neurofibroma]] is not [[surgery|surgery,]]<ref>{{cite journal |vauthors=Packer RJ, Gutmann DH, Rubenstein A, etal |title=Plexiform neurofibromas in NF1: toward biologic-based therapy |journal=Neurology |volume=58 |issue=10 |pages=1461–70 |date=May 2002 |pmid=12041525 |url=http://www.neurology.org/cgi/pmidlookup?view=long&pmid=12041525 |doi=10.1212/wnl.58.10.1461}}</ref><ref name="radio" /> until and unless debilitating symptoms are present | * The primary treatment option for [[plexiform neurofibroma]] is not [[surgery|surgery,]]<ref>{{cite journal |vauthors=Packer RJ, Gutmann DH, Rubenstein A, etal |title=Plexiform neurofibromas in NF1: toward biologic-based therapy |journal=Neurology |volume=58 |issue=10 |pages=1461–70 |date=May 2002 |pmid=12041525 |url=http://www.neurology.org/cgi/pmidlookup?view=long&pmid=12041525 |doi=10.1212/wnl.58.10.1461}}</ref><ref name="radio" /> until and unless debilitating symptoms are present and if there is a possibility of malignant transformation | ||
* Removal of [[plexiform neurofibroma]]s is difficult because they can be large and cross [[tissue]] boundaries hence, leading to incomplete resection | * Removal of [[plexiform neurofibroma]]s is difficult because they can be large and cross [[tissue]] boundaries hence, leading to incomplete resection | ||
* Recurrence after resection is frequent | * Recurrence after resection is frequent | ||
Revision as of 16:02, 3 April 2019
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Neurofibroma Microchapters |
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Treatment |
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Neurofibroma surgery On the Web |
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American Roentgen Ray Society Images of Neurofibroma surgery |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2] Shanshan Cen, M.D. [3]
Overview
Surgery is the mainstay of treatment for neurofibroma.
Surgery
Localised neurofibroma and Diffuse neurofibroma (not associated with NF-1)
- Localised and diffuse lesions usually be treated surgically[1]
- Neurofibromas that infiltrate between nerve fascicles are unable to be separated from the parent nerve, therefore, deep-seated lesions are often managed conservatively
- Local recurrence after excision is uncommon and malignant transformation is rare
Plexiform neurofibroma (NF-1 associated)
- The primary treatment option for plexiform neurofibroma is not surgery,[2][1] until and unless debilitating symptoms are present and if there is a possibility of malignant transformation
- Removal of plexiform neurofibromas is difficult because they can be large and cross tissue boundaries hence, leading to incomplete resection
- Recurrence after resection is frequent
References
- ↑ 1.0 1.1 Neurofibroma. Dr Bruno Di Muzio and Dr Maxime St-Amant et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/neurofibroma Accessed on November 17, 2015
- ↑ Packer RJ, Gutmann DH, Rubenstein A, et al. (May 2002). "Plexiform neurofibromas in NF1: toward biologic-based therapy". Neurology. 58 (10): 1461–70. doi:10.1212/wnl.58.10.1461. PMID 12041525.