Vulvar cancer natural history: Difference between revisions
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==Complications== | ==Complications== | ||
* [[Pelvic pain]]<ref name="pmid29121621">{{cite journal |vauthors=Dass PH, Kuper-Hommel MJ |title=A review of squamous cell vulvar cancers in Waikato region, New Zealand |journal=N. Z. Med. J. |volume=130 |issue=1465 |pages=19–28 |date=November 2017 |pmid=29121621 |doi= |url=}}</ref> | * [[Pelvic pain]]<ref name="pmid29121621">{{cite journal |vauthors=Dass PH, Kuper-Hommel MJ |title=A review of squamous cell vulvar cancers in Waikato region, New Zealand |journal=N. Z. Med. J. |volume=130 |issue=1465 |pages=19–28 |date=November 2017 |pmid=29121621 |doi= |url=}}</ref><ref name="pmid30932169">{{cite journal |vauthors=Wiggans A, Coleridge S, Bryant A, Morrison J |title=Relationship between vulvar symptoms and incidence of vulvar cancer in women referred to a rapid access clinic |journal=Int J Gynaecol Obstet |volume= |issue= |pages= |date=April 2019 |pmid=30932169 |doi=10.1002/ijgo.12818 |url=}}</ref> | ||
* Fistula | * Fistula | ||
*[[Metastasis]] - usually in the liver and lungs but may occur in other sites | *[[Metastasis]] - usually in the liver and lungs but may occur in other sites | ||
Revision as of 19:51, 10 April 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Monalisa Dmello, M.B,B.S., M.D. [2] Syed Musadiq Ali M.B.B.S.[3]
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Risk calculators and risk factors for Vulvar cancer natural history |
Overview
If left untreated, patients with vulvar cancer may progress to develop ulcer on vulva or wart-like patches on vulva and chronic pruritus of the vulva. Common complications of vulvar cancer include fistula and metastasis. Prognosis is generally good, and the 5 year survival rate of patients with vulvar cancer is approximately 71.2%.[1]
Natural history
- Patient has early symptoms like ulcer on vulva, chronic pruritus of the vulva, and wart-like patches on vulva.
- As the tumor grows larger, patient may notice symptoms like unusual bleeding or discharge from the lesion, large mass on the vulva, dysuria, and dyspareunia.
- In advanced disease, metastases may be present in the abdomen and lungs.
- The patient may present with dyspnea, cough with blood-stained sputum, persistent pain or discomfort in the chest, edema hands/feet, and inguinal lymphadenopathy.
- Once the cancer spreads to the other organs, it is most likely fatal.
Complications
- Pelvic pain[2][3]
- Fistula
- Metastasis - usually in the liver and lungs but may occur in other sites
Prognosis
- Vulvar cancer is associated with a 5 year survival rate of 71.2%.
- Following is a table illustrating the survival of patients with vulvar squamous cell carcinoma.[1]
| Stage | 5-year relative survival (%) |
| I | 93% |
| II | 79% |
| III | 53% |
| IV | 29% |
References
- ↑ 1.0 1.1 Survival statistics for vulvar cancer. Vulvar cancer. http://www.cancer.ca/en/cancer-information/cancer-type/vulvar/prognosis-and-survival/survival-statistics/?region=ns Accessed on October 1, 2015
- ↑ Dass PH, Kuper-Hommel MJ (November 2017). "A review of squamous cell vulvar cancers in Waikato region, New Zealand". N. Z. Med. J. 130 (1465): 19–28. PMID 29121621.
- ↑ Wiggans A, Coleridge S, Bryant A, Morrison J (April 2019). "Relationship between vulvar symptoms and incidence of vulvar cancer in women referred to a rapid access clinic". Int J Gynaecol Obstet. doi:10.1002/ijgo.12818. PMID 30932169.