Mucinous cystadenocarcinoma differential diagnosis: Difference between revisions

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Revision as of 17:14, 11 April 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Mucinous cystadenocarcinoma must be differentiated from mucinous cystadenoma, serous cystadenoma, and pseudocyst.

Differentiating Mucinous cystadenocarcinoma from other Diseases

Mucinous cystadenocarcinoma of ovary

Mucinous borderline tumor of the ovary
Metastatic mucinous carcinoma^[1]

Mucinous cystadenocarcinoma of pancreas

Mucinous cystadenoma of pancreas
Pancreatic pseudocyst
Serous cystadenoma of pancreas

Mucinous cystadenocarcinoma of appendix

Appendicitis
Nonmucinous appendiceal tumors
Mesenteric cyst^[2]^[3]

			Lab Findings	Imaging			Histopathology
Mucinous cystadenocarcinoma of ovary	Clinical manifestations		Para-clinical findings					Gold standard
	Sign and symptoms	Physical examination	Para-clinical findings
			Lab Findings	US	CT	MRI	Histopathology
Mucinous borderline tumor of the ovary	Asymptomatic initially Vaginal bleeding Abdominal mass	Increased abdominal girth Abdominal mass	Decreased Hb	To localize the tumor	To demarcate the cancer	To see the extent of the tumor		Image guided biopsy and histopathological analysis
Metastatic mucinous carcinoma^[4]	Ascities Abdominal mass Abdominal fullness Early satiety Fatigue Bowel obstruction Pleural effusion Pelvic or abdominal pain Venous thromboembolism Bloating Urinary frequency	Increased abdominal girth Abdominal mass Ascities Pallor Lymphadenopathy	Incresed CA-125 Decreased-Hb	To assess for ascites and the extent of cancer	To see intra-abdominal spread	Shows distant metastasis and extent of the tumor	Shows	Image-guided biopsy of patients with peritoneal metastasis and histopathological analysis

Mucinous cystadenocarcinoma of pancreas	Symptoms	Physical examination	Lab Findings	US	CT	MRI	Histopathology	Gold standard
Mucinous cystadenoma of pancreas
Pancreatic pseudocyst
Serous cystadenoma of pancreas



Mucinous cystadenocarcinoma of appendix	Symptoms	Physical examination	Lab 1	US	CT	MRI	Histopathology	Gold standard
Appendicitis
Nonmucinous appendiceal tumors
Mesenteric cyst^[2]

References

↑ Ovary Epithelial tumors. Atlasgeneticsoncology (2016).http://atlasgeneticsoncology.org/Tumors/OvaryEpithTumID5230.html Accessed on February 29, 2016
↑ ^2.0 ^2.1 Hamilton DL, Stormont JM (1989). "The volcano sign of appendiceal mucocele". Gastrointest. Endosc. 35 (5): 453–6. PMID 2792684.
↑ Raijman I, Leong S, Hassaram S, Marcon NE (March 1994). "Appendiceal mucocele: endoscopic appearance". Endoscopy. 26 (3): 326–8. doi:10.1055/s-2007-1008979. PMID 8076556.
↑ Hewitt MJ, Anderson K, Hall GD, Weston M, Hutson R, Wilkinson N, Perren TJ, Lane G, Spencer JA (January 2007). "Women with peritoneal carcinomatosis of unknown origin: Efficacy of image-guided biopsy to determine site-specific diagnosis". BJOG. 114 (1): 46–50. doi:10.1111/j.1471-0528.2006.01176.x. PMID 17233859.

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[1] Ovary Epithelial tumors. Atlasgeneticsoncology (2016).http://atlasgeneticsoncology.org/Tumors/OvaryEpithTumID5230.html Accessed on February 29, 2016

[pmid2792684-2] 2.0 ^2.1 Hamilton DL, Stormont JM (1989). "The volcano sign of appendiceal mucocele". Gastrointest. Endosc. 35 (5): 453–6. PMID 2792684.

[pmid8076556-3] Raijman I, Leong S, Hassaram S, Marcon NE (March 1994). "Appendiceal mucocele: endoscopic appearance". Endoscopy. 26 (3): 326–8. doi:10.1055/s-2007-1008979. PMID 8076556.

[pmid17233859-4] Hewitt MJ, Anderson K, Hall GD, Weston M, Hutson R, Wilkinson N, Perren TJ, Lane G, Spencer JA (January 2007). "Women with peritoneal carcinomatosis of unknown origin: Efficacy of image-guided biopsy to determine site-specific diagnosis". BJOG. 114 (1): 46–50. doi:10.1111/j.1471-0528.2006.01176.x. PMID 17233859.

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 * Decreased Hb
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+* To localize the tumor
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+* To demarcate the cancer
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+* To see the extent of the tumor
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+* Image guided biopsy and histopathological analysis
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 | style="background: #DCDCDC; padding: 5px; text-align: center;" |Metastatic
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 mucinous
-carcinoma
+carcinoma<ref name="pmid17233859">{{cite journal |vauthors=Hewitt MJ, Anderson K, Hall GD, Weston M, Hutson R, Wilkinson N, Perren TJ, Lane G, Spencer JA |title=Women with peritoneal carcinomatosis of unknown origin: Efficacy of image-guided biopsy to determine site-specific diagnosis |journal=BJOG |volume=114 |issue=1 |pages=46–50 |date=January 2007 |pmid=17233859 |doi=10.1111/j.1471-0528.2006.01176.x |url=}}</ref>
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 * Ascities
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 * Decreased-Hb
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+* To assess for ascites and
+the extent of cancer
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+* To see intra-abdominal spread
 | style="background: #F5F5F5; padding: 5px;" |
+* Shows distant metastasis and extent of the tumor
 | style="background: #F5F5F5; padding: 5px;" |
+* Shows
 | style="background: #F5F5F5; padding: 5px;" |
+* Image-guided biopsy of patients with peritoneal metastasis and histopathological analysis
 |-
 | style="background: #DCDCDC; padding: 5px; text-align: center;" |