Retinoblastoma historical perspective: Difference between revisions
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Retinoblastoma was first described in 1809 by James Wardrop.<ref name="pmid3306547">{{cite journal| author=Albert DM| title=Historic review of retinoblastoma. | journal=Ophthalmology | year= 1987 | volume= 94 | issue= 6 | pages= 654-62 | pmid=3306547 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3306547 }} </ref> | Retinoblastoma was first described in 1809 by James Wardrop.<ref name="pmid3306547">{{cite journal| author=Albert DM| title=Historic review of retinoblastoma. | journal=Ophthalmology | year= 1987 | volume= 94 | issue= 6 | pages= 654-62 | pmid=3306547 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3306547 }} </ref> | ||
==Historical Perspective == | ==Historical Perspective == | ||
* | *In 1809, Dr. James Wardrop, Scottish surgeon and ophthalmologist, first described the retinoblastoma tumor.<ref name="pmid3306547">{{cite journal| author=Albert DM| title=Historic review of retinoblastoma. | journal=Ophthalmology | year= 1987 | volume= 94 | issue= 6 | pages= 654-62 | pmid=3306547 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3306547 }} </ref> | ||
*In 1971, Dr. Knudson proposed the two-hit hypothesis which give the light to the pathogenesis of the familial and sporadic form of the tumor.<ref name="pmid5279523">{{cite journal |vauthors=Knudson AG |title=Mutation and cancer: statistical study of retinoblastoma |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=68 |issue=4 |pages=820–3 |date=April 1971 |pmid=5279523 |pmc=389051 |doi= |url=}}</ref> | |||
*In 1899, Flexner and Wintersteiner were the first to discover the association between tumor rosettes and photoreceptors of the adult retina. | *In 1899, Flexner and Wintersteiner were the first to discover the association between tumor rosettes and photoreceptors of the adult retina. | ||
*In 1920s Verhoeff claimed that the tumor arose from embryonic retinal cells and hence proposed the name "retinoblastoma". | *In 1920s Verhoeff claimed that the tumor arose from embryonic retinal cells and hence proposed the name "retinoblastoma". | ||
Revision as of 20:28, 18 April 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
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Overview
Retinoblastoma was first described in 1809 by James Wardrop.[1]
Historical Perspective
- In 1809, Dr. James Wardrop, Scottish surgeon and ophthalmologist, first described the retinoblastoma tumor.[1]
- In 1971, Dr. Knudson proposed the two-hit hypothesis which give the light to the pathogenesis of the familial and sporadic form of the tumor.[2]
- In 1899, Flexner and Wintersteiner were the first to discover the association between tumor rosettes and photoreceptors of the adult retina.
- In 1920s Verhoeff claimed that the tumor arose from embryonic retinal cells and hence proposed the name "retinoblastoma".