Retinoblastoma staging: Difference between revisions

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{|
|- style="background: #4479BA; color: #FFFFFF; text-align: center;"
|- style="background: #4479BA; color: #FFFFFF; text-align: center;"
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Stage
| colspan="6" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |
| colspan="6" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Description
|-
|-
| style="background: #DCDCDC; padding: 5px; text-align: center;" |
| style="background: #DCDCDC; padding: 5px; text-align: center;" |Stage 0
| colspan="6" style="background: #F5F5F5; padding: 5px;" |
| colspan="6" style="background: #F5F5F5; padding: 5px;" |Eye enucleated and no dissemination of the disease
|-
|-
| style="background: #DCDCDC; padding: 5px; text-align: center;" |
| style="background: #DCDCDC; padding: 5px; text-align: center;" |Stage I
| colspan="6" style="background: #F5F5F5; padding: 5px;" |
| colspan="6" style="background: #F5F5F5; padding: 5px;" |Eye enucleated, completely resected histologically
|-
|-
| style="background: #DCDCDC; padding: 5px; text-align: center;" |
| style="background: #DCDCDC; padding: 5px; text-align: center;" |Stage II
| colspan="6" style="background: #F5F5F5; padding: 5px;" |
| colspan="6" style="background: #F5F5F5; padding: 5px;" |Eye enucleated, microscopic residual tumor
|-
|-
| style="background: #DCDCDC; padding: 5px; text-align: center;" |
| style="background: #DCDCDC; padding: 5px; text-align: center;" |Stage III
| colspan="3" style="background: #F5F5F5; padding: 5px;" |
| colspan="3" style="background: #F5F5F5; padding: 5px;" |Regional extension
| colspan="3" style="background: #F5F5F5; padding: 5px;" |
| colspan="3" style="background: #F5F5F5; padding: 5px;" |a.Overt orbital disease
 
b.Preauricular or cervical lymph node extension
|-
|-
| style="background: #DCDCDC; padding: 5px; text-align: center;" |
| style="background: #DCDCDC; padding: 5px; text-align: center;" |Stage IV
| colspan="3" style="background: #F5F5F5; padding: 5px;" |
| colspan="3" style="background: #F5F5F5; padding: 5px;" |Metastatic disease
| colspan="3" style="background: #F5F5F5; padding: 5px;" |
| colspan="3" style="background: #F5F5F5; padding: 5px;" |a.Hematogenous metastasis (without CNS involvement)
 
—Single lesion
 
—Multiple lesions
 
b.CNS extension (with or without any other site of regional or metastatic disease)
 
—Prechiasmatic lesion
 
—CNS mass
 
—Leptomeningeal and CSF disease
|}
|}



Revision as of 15:44, 25 April 2019

Retinoblastoma Microchapters

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Patient Information

Overview

Historical perspective

Classification

Pathophysiology

Causes

Differentiating Retinoblastoma from other Diseases

Epidemiology & Demographics

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Diagnosis

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Retinoblastoma staging On the Web

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NICE Guidance

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Directions to Hospitals Treating Retinoblastoma

Risk calculators and risk factors for Retinoblastoma staging

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]

Overview

According to the International classification of retinoblastoma, there are five stages of retinoblastoma based on the tumor size, location, local spread, neovascular glaucoma, intravascular hemorrhage, and orbital cellulitis.

Staging

  • There is two known staging system for retinoblastoma:
    • American Joint Committee on Cancer (AJCC) staging system
    • International Retinoblastoma Staging System
      • This staging system is used in the clinical setting greater than the AJCC staging system.
Stage Description
Stage 0 Eye enucleated and no dissemination of the disease
Stage I Eye enucleated, completely resected histologically
Stage II Eye enucleated, microscopic residual tumor
Stage III Regional extension a.Overt orbital disease

b.Preauricular or cervical lymph node extension

Stage IV Metastatic disease a.Hematogenous metastasis (without CNS involvement)

—Single lesion

—Multiple lesions

b.CNS extension (with or without any other site of regional or metastatic disease)

—Prechiasmatic lesion

—CNS mass

—Leptomeningeal and CSF disease