Seminoma natural history, complications and prognosis: Difference between revisions
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==Prognosis== | ==Prognosis== | ||
*Prognosis for stage I is excellent, and the survival rate of patients with seminoma for satgr I is approximately 100%.<ref name="pmid26893743">{{cite journal |vauthors=Dong W, Gang W, Liu M, Zhang H |title=Analysis of the prognosis of patients with testicular seminoma |journal=Oncol Lett |volume=11 |issue=2 |pages=1361–1366 |date=February 2016 |pmid=26893743 |pmc=4734256 |doi=10.3892/ol.2015.4065 |url=}}</ref> | *Prognosis for stage I is excellent, and the survival rate of patients with seminoma for satgr I is approximately 100%.<ref name="pmid26893743">{{cite journal |vauthors=Dong W, Gang W, Liu M, Zhang H |title=Analysis of the prognosis of patients with testicular seminoma |journal=Oncol Lett |volume=11 |issue=2 |pages=1361–1366 |date=February 2016 |pmid=26893743 |pmc=4734256 |doi=10.3892/ol.2015.4065 |url=}}</ref><ref name="HoneckerAparicio2018">{{cite journal|last1=Honecker|first1=F|last2=Aparicio|first2=J|last3=Berney|first3=D|last4=Beyer|first4=J|last5=Bokemeyer|first5=C|last6=Cathomas|first6=R|last7=Clarke|first7=N|last8=Cohn-Cedermark|first8=G|last9=Daugaard|first9=G|last10=Dieckmann|first10=K -P|last11=Fizazi|first11=K|last12=Fosså|first12=S|last13=Germa-Lluch|first13=J R|last14=Giannatempo|first14=P|last15=Gietema|first15=J A|last16=Gillessen|first16=S|last17=Haugnes|first17=H S|last18=Heidenreich|first18=A|last19=Hemminki|first19=K|last20=Huddart|first20=R|last21=Jewett|first21=M A S|last22=Joly|first22=F|last23=Lauritsen|first23=J|last24=Lorch|first24=A|last25=Necchi|first25=A|last26=Nicolai|first26=N|last27=Oing|first27=C|last28=Oldenburg|first28=J|last29=Ondruš|first29=D|last30=Papachristofilou|first30=A|last31=Powles|first31=T|last32=Sohaib|first32=A|last33=Ståhl|first33=O|last34=Tandstad|first34=T|last35=Toner|first35=G|last36=Horwich|first36=A|title=ESMO Consensus Conference on testicular germ cell cancer: diagnosis, treatment and follow-up|journal=Annals of Oncology|volume=29|issue=8|year=2018|pages=1658–1686|issn=0923-7534|doi=10.1093/annonc/mdy217}}</ref> | ||
*Prognosis for stage II is generally good, the 5-year mortality survival rate of patients with satge II of seminoma is approximately 97%. | *Prognosis for stage II is generally good, the 5-year mortality survival rate of patients with satge II of seminoma is approximately 97%. | ||
*Prognosis for stage III is generally good, the 5-year mortality survival rate of patients with satge II of seminoma is approximately 85% | *Prognosis for stage III is generally good, the 5-year mortality survival rate of patients with satge II of seminoma is approximately 85% | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
Seminoma grows slower than non-seminomatous germ cell tumors. Common complications of seminoma include recurrence, lymph node metastasis, distant metastasis, and secondary malignancies. Prognosis of seminoma is good for all stages with greater than 90% cure rate. The International Germ Cell Cancer Consensus Group divides seminoma into two prognosis groups: good and intermediate.
Natural History
Seminoma grows slower than non-seminomatous germ cell tumors.[1]
Complications
Common complications of seminoma include:[2]
- Recurrence
- Lymph node metastasis
- Distant metastasis
- Increased risk of seminoma in the remaining testicle
- Increased risk of other cancers (second malignancies)
Prognosis
- Prognosis for stage I is excellent, and the survival rate of patients with seminoma for satgr I is approximately 100%.[3][4]
- Prognosis for stage II is generally good, the 5-year mortality survival rate of patients with satge II of seminoma is approximately 97%.
- Prognosis for stage III is generally good, the 5-year mortality survival rate of patients with satge II of seminoma is approximately 85%
References
- ↑ Cancerous tumours of the testicle. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/testicular/testicular-cancer/cancerous-tumours/?region=on. Accessed on February 26, 2016
- ↑ Testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on March 3, 2016
- ↑ Dong W, Gang W, Liu M, Zhang H (February 2016). "Analysis of the prognosis of patients with testicular seminoma". Oncol Lett. 11 (2): 1361–1366. doi:10.3892/ol.2015.4065. PMC 4734256. PMID 26893743.
- ↑ Honecker, F; Aparicio, J; Berney, D; Beyer, J; Bokemeyer, C; Cathomas, R; Clarke, N; Cohn-Cedermark, G; Daugaard, G; Dieckmann, K -P; Fizazi, K; Fosså, S; Germa-Lluch, J R; Giannatempo, P; Gietema, J A; Gillessen, S; Haugnes, H S; Heidenreich, A; Hemminki, K; Huddart, R; Jewett, M A S; Joly, F; Lauritsen, J; Lorch, A; Necchi, A; Nicolai, N; Oing, C; Oldenburg, J; Ondruš, D; Papachristofilou, A; Powles, T; Sohaib, A; Ståhl, O; Tandstad, T; Toner, G; Horwich, A (2018). "ESMO Consensus Conference on testicular germ cell cancer: diagnosis, treatment and follow-up". Annals of Oncology. 29 (8): 1658–1686. doi:10.1093/annonc/mdy217. ISSN 0923-7534.