Renal oncocytoma history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2] Shanshan Cen, M.D. [3]

Overview

Symptoms of renal oncocytoma include hematuria and flank pain.

Symptoms

Renal oncocytomas are often asymptomatic. Possible symptoms of a renal oncocytoma include:

• Hematuria
• Flank pain

Overview

The majority of patients with [disease name] are asymptomatic.

OR

The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].

History and Symptoms

• The majority of patients with [disease name] are asymptomatic.

OR

• The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
• Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. 

History

Patients with [disease name]] may have a positive history of:

• [History finding 1]
• [History finding 2]
• [History finding 3]

Common Symptoms

Common symptoms of [disease] include:

• [Symptom 1]
• [Symptom 2]
• [Symptom 3]

Less Common Symptoms

Less common symptoms of [disease name] include

• [Symptom 1]
• [Symptom 2]
• [Symptom 3]

Because of their well-circumscribed, generally noninvasive growth pattern few renal oncocytomas are symptomatic, but are instead detected incidentally during an evaluation for some unrelated symptom, or even at postmortem examination. This feature was noted in Klein and Valensi’s [2] initial series and has been validated by contemporary reports, which suggest that only 17% to 21% of patients with oncocytoma present with symptoms [2,4,7]. Gross hematuria precipitated work-up in 3% to 9% of patients, flank pain in 3% to 4%, and abdominal mass in 3% to 4% [4,7].

More than 50% of patients with oncocytomas are asymptomatic . Flank pain, a palpable mass, gross or microscopic hematuria, or weight loss is seen in some patients .

Other clinical features: Bilateral or multifocal oncocytomas are sometimes seen The coexistence of oncocytoma and renal cell carcinoma has also been reported. An association with angiomyolipoma or tuberculous sclerosis in some patients has been reported . The occurrence of oncocytoma in transplant patients has also been reported (Rostaing et al., 1994). Familial cases of oncocytoma have also been found .