Renal oncocytoma history and symptoms: Difference between revisions
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Homa Najafi (talk | contribs) |
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{{Renal Oncocytoma}} | {{Renal Oncocytoma}} | ||
{{CMG}}; {{AE}}{{Homa}} {{SC}} | {{CMG}}; {{AE}}{{Homa}} {{SC}} | ||
==Overview== | ==Overview== | ||
The majority of patients with [disease name] are asymptomatic. | The majority of patients with [disease name] are asymptomatic. | ||
Line 19: | Line 10: | ||
==History and Symptoms== | ==History and Symptoms== | ||
*The majority of patients with [ | *The majority of patients with renal oncocytoma are asymptomatic.<ref>{{Cite journal | ||
| author = [[H. Choi]], [[U. A. Almagro]], [[J. T. McManus]], [[D. H. Norback]] & [[S. C. Jacobs]] | |||
* | | title = Renal oncocytoma. A clinicopathologic study | ||
| journal = [[Cancer]] | |||
=== | | volume = 51 | ||
| issue = 10 | |||
*[ | | pages = 1887–1896 | ||
| year = 1983 | |||
| month = May | |||
| pmid = 6831354 | |||
=== | }}</ref><ref>{{Cite journal | ||
| author = [[M. B. Amin]], [[T. B. Crotty]], [[S. K. Tickoo]] & [[G. M. Farrow]] | |||
| title = Renal oncocytoma: a reappraisal of morphologic features with clinicopathologic findings in 80 cases | |||
| journal = [[The American journal of surgical pathology]] | |||
| volume = 21 | |||
| issue = 1 | |||
=== | | pages = 1–12 | ||
| year = 1997 | |||
| month = January | |||
| pmid = 8990136 | |||
}}</ref> | |||
*Symptoms are seen in almost 17% to 21% of patients with renal oncocytoma. | |||
*Symptoms of renal oncocytoma include [[hematuria]], [[flank pain]], [[abdominal mass]] and [[weight loss]].<ref>{{Cite journal | |||
| author = [[B. Perez-Ordonez]], [[G. Hamed]], [[S. Campbell]], [[R. A. Erlandson]], [[P. Russo]], [[P. B. Gaudin]] & [[V. E. Reuter]] | |||
| title = Renal oncocytoma: a clinicopathologic study of 70 cases | |||
| journal = [[The American journal of surgical pathology]] | |||
| volume = 21 | |||
| issue = 8 | |||
| pages = 871–883 | |||
| year = 1997 | |||
| month = August | |||
| pmid = 9255250 | |||
}}</ref><ref>{{Cite journal | |||
| author = [[M. M. Lieber]], [[K. M. Tomera]] & [[G. M. Farrow]] | |||
| title = Renal oncocytoma | |||
| journal = [[The Journal of urology]] | |||
| volume = 125 | |||
| issue = 4 | |||
| pages = 481–485 | |||
| year = 1981 | |||
| month = April | |||
| pmid = 7218443 | |||
}}</ref><ref name="NeisiusBraedel1988">{{cite journal|last1=Neisius|first1=D.|last2=Braedel|first2=H. U.|last3=Schindler|first3=E.|last4=Hoene|first4=E.|last5=Alloussi|first5=Sch.|title=Computed tomographic and angiographic findings in renal oncocytoma|journal=The British Journal of Radiology|volume=61|issue=731|year=1988|pages=1019–1025|issn=0007-1285|doi=10.1259/0007-1285-61-731-1019}}</ref><ref>{{Cite journal | |||
| author = [[M. R. Licht]], [[A. C. Novick]], [[R. R. Tubbs]], [[E. A. Klein]], [[H. S. Levin]] & [[S. B. Streem]] | |||
| title = Renal oncocytoma: clinical and biological correlates | |||
| journal = [[The Journal of urology]] | |||
| volume = 150 | |||
| issue = 5 Pt 1 | |||
| pages = 1380–1383 | |||
| year = 1993 | |||
| month = November | |||
| pmid = 8411404 | |||
}}</ref><ref>{{Cite journal | |||
| author = [[F. Bertoni]], [[C. Ferri]], [[P. Bacchini]], [[G. Corrado]], [[A. Benati]], [[D. Mannini]] & [[F. Corrado]] | |||
| title = Oncocytoma and low-grade oncocytic carcinoma of the kidney | |||
| journal = [[European urology]] | |||
| volume = 16 | |||
| issue = 2 | |||
| pages = 101–109 | |||
| year = 1989 | |||
| month = | |||
| pmid = 2714326 | |||
}}</ref><ref>{{Cite journal | |||
| author = [[C. B. Dechet]], [[D. G. Bostwick]], [[M. L. Blute]], [[S. C. Bryant]] & [[H. Zincke]] | |||
| title = Renal oncocytoma: multifocality, bilateralism, metachronous tumor development and coexistent renal cell carcinoma | |||
| journal = [[The Journal of urology]] | |||
| volume = 162 | |||
| issue = 1 | |||
| pages = 40–42 | |||
| year = 1999 | |||
| month = July | |||
| doi = 10.1097/00005392-199907000-00010 | |||
| pmid = 10379735 | |||
}}</ref> | |||
===Symptoms=== | |||
Symptoms of renal oncocytoma include:<ref>{{Cite journal | |||
| author = [[H. Choi]], [[U. A. Almagro]], [[J. T. McManus]], [[D. H. Norback]] & [[S. C. Jacobs]] | |||
| title = Renal oncocytoma. A clinicopathologic study | |||
| journal = [[Cancer]] | |||
| volume = 51 | |||
| issue = 10 | |||
| pages = 1887–1896 | |||
| year = 1983 | |||
| month = May | |||
| pmid = 6831354 | |||
}}</ref><ref>{{Cite journal | |||
| author = [[M. B. Amin]], [[T. B. Crotty]], [[S. K. Tickoo]] & [[G. M. Farrow]] | |||
| title = Renal oncocytoma: a reappraisal of morphologic features with clinicopathologic findings in 80 cases | |||
| journal = [[The American journal of surgical pathology]] | |||
| volume = 21 | |||
| issue = 1 | |||
| pages = 1–12 | |||
| year = 1997 | |||
| month = January | |||
| pmid = 8990136 | |||
}}</ref> | |||
*Symptoms are seen in almost 17% to 21% of patients with renal oncocytoma. | |||
*Symptoms of renal oncocytoma include [[hematuria]], [[flank pain]], [[abdominal mass]] and [[weight loss]].<ref>{{Cite journal | |||
| author = [[B. Perez-Ordonez]], [[G. Hamed]], [[S. Campbell]], [[R. A. Erlandson]], [[P. Russo]], [[P. B. Gaudin]] & [[V. E. Reuter]] | |||
| title = Renal oncocytoma: a clinicopathologic study of 70 cases | |||
| journal = [[The American journal of surgical pathology]] | |||
| volume = 21 | |||
| issue = 8 | |||
| pages = 871–883 | |||
| year = 1997 | |||
| month = August | |||
| pmid = 9255250 | |||
}}</ref><ref>{{Cite journal | |||
| author = [[M. M. Lieber]], [[K. M. Tomera]] & [[G. M. Farrow]] | |||
| title = Renal oncocytoma | |||
| journal = [[The Journal of urology]] | |||
| volume = 125 | |||
| issue = 4 | |||
| pages = 481–485 | |||
| year = 1981 | |||
| month = April | |||
| pmid = 7218443 | |||
}}</ref><ref name="NeisiusBraedel1988">{{cite journal|last1=Neisius|first1=D.|last2=Braedel|first2=H. U.|last3=Schindler|first3=E.|last4=Hoene|first4=E.|last5=Alloussi|first5=Sch.|title=Computed tomographic and angiographic findings in renal oncocytoma|journal=The British Journal of Radiology|volume=61|issue=731|year=1988|pages=1019–1025|issn=0007-1285|doi=10.1259/0007-1285-61-731-1019}}</ref><ref>{{Cite journal | |||
| author = [[M. R. Licht]], [[A. C. Novick]], [[R. R. Tubbs]], [[E. A. Klein]], [[H. S. Levin]] & [[S. B. Streem]] | |||
| title = Renal oncocytoma: clinical and biological correlates | |||
| journal = [[The Journal of urology]] | |||
| volume = 150 | |||
| issue = 5 Pt 1 | |||
| pages = 1380–1383 | |||
| year = 1993 | |||
| month = November | |||
| pmid = 8411404 | |||
}}</ref><ref>{{Cite journal | |||
| author = [[F. Bertoni]], [[C. Ferri]], [[P. Bacchini]], [[G. Corrado]], [[A. Benati]], [[D. Mannini]] & [[F. Corrado]] | |||
| title = Oncocytoma and low-grade oncocytic carcinoma of the kidney | |||
| journal = [[European urology]] | |||
| volume = 16 | |||
| issue = 2 | |||
| pages = 101–109 | |||
| year = 1989 | |||
| month = | |||
| pmid = 2714326 | |||
}}</ref><ref>{{Cite journal | |||
| author = [[C. B. Dechet]], [[D. G. Bostwick]], [[M. L. Blute]], [[S. C. Bryant]] & [[H. Zincke]] | |||
| title = Renal oncocytoma: multifocality, bilateralism, metachronous tumor development and coexistent renal cell carcinoma | |||
| journal = [[The Journal of urology]] | |||
| volume = 162 | |||
| issue = 1 | |||
| pages = 40–42 | |||
| year = 1999 | |||
| month = July | |||
| doi = 10.1097/00005392-199907000-00010 | |||
| pmid = 10379735 | |||
}}</ref> | |||
*[[Hematuria]] | |||
*[[Flank pain]] | |||
*[[Abdominal mass]] | |||
*[[Weight loss]] | |||
Less common symptoms of [disease name] include | Less common symptoms of [disease name] include | ||
*[Symptom 1] | *[Symptom 1] | ||
Line 41: | Line 169: | ||
*[Symptom 3] | *[Symptom 3] | ||
Because of their well-circumscribed, generally noninvasive growth pattern few renal oncocytomas are symptomatic | Because of their well-circumscribed, generally noninvasive growth pattern few renal oncocytomas are symptomatic but are instead detected incidentally during an evaluation for some unrelated symptom, or even at postmortem examination. This feature was noted in Klein and Valensi’s [2] initial series and has been validated by contemporary reports, which suggest that only 17% to 21% of patients with oncocytoma present with symptoms [2,4,7]. Gross hematuria precipitated work-up in 3% to 9% of patients, flank pain in 3% to 4%, and abdominal mass in 3% to 4% [4,7]. | ||
More than 50% of patients with oncocytomas are asymptomatic . Flank pain, a palpable mass, gross or microscopic hematuria, or weight loss is seen in some patients . | More than 50% of patients with oncocytomas are asymptomatic . Flank pain, a palpable mass, gross or microscopic hematuria, or weight loss is seen in some patients . |
Revision as of 17:48, 8 May 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2] Shanshan Cen, M.D. [3]
Overview
The majority of patients with [disease name] are asymptomatic.
OR
The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
History and Symptoms
- The majority of patients with renal oncocytoma are asymptomatic.[1][2]
- Symptoms are seen in almost 17% to 21% of patients with renal oncocytoma.
- Symptoms of renal oncocytoma include hematuria, flank pain, abdominal mass and weight loss.[3][4][5][6][7][8]
Symptoms
Symptoms of renal oncocytoma include:[9][10]
- Symptoms are seen in almost 17% to 21% of patients with renal oncocytoma.
- Symptoms of renal oncocytoma include hematuria, flank pain, abdominal mass and weight loss.[11][12][5][13][14][15]
- Hematuria
- Flank pain
- Abdominal mass
- Weight loss
Less common symptoms of [disease name] include
- [Symptom 1]
- [Symptom 2]
- [Symptom 3]
Because of their well-circumscribed, generally noninvasive growth pattern few renal oncocytomas are symptomatic but are instead detected incidentally during an evaluation for some unrelated symptom, or even at postmortem examination. This feature was noted in Klein and Valensi’s [2] initial series and has been validated by contemporary reports, which suggest that only 17% to 21% of patients with oncocytoma present with symptoms [2,4,7]. Gross hematuria precipitated work-up in 3% to 9% of patients, flank pain in 3% to 4%, and abdominal mass in 3% to 4% [4,7].
More than 50% of patients with oncocytomas are asymptomatic . Flank pain, a palpable mass, gross or microscopic hematuria, or weight loss is seen in some patients .
Other clinical features: Bilateral or multifocal oncocytomas are sometimes seen The coexistence of oncocytoma and renal cell carcinoma has also been reported. An association with angiomyolipoma or tuberculous sclerosis in some patients has been reported . The occurrence of oncocytoma in transplant patients has also been reported (Rostaing et al., 1994). Familial cases of oncocytoma have also been found .
References
- ↑ H. Choi, U. A. Almagro, J. T. McManus, D. H. Norback & S. C. Jacobs (1983). "Renal oncocytoma. A clinicopathologic study". Cancer. 51 (10): 1887–1896. PMID 6831354. Unknown parameter
|month=
ignored (help) - ↑ M. B. Amin, T. B. Crotty, S. K. Tickoo & G. M. Farrow (1997). "Renal oncocytoma: a reappraisal of morphologic features with clinicopathologic findings in 80 cases". The American journal of surgical pathology. 21 (1): 1–12. PMID 8990136. Unknown parameter
|month=
ignored (help) - ↑ B. Perez-Ordonez, G. Hamed, S. Campbell, R. A. Erlandson, P. Russo, P. B. Gaudin & V. E. Reuter (1997). "Renal oncocytoma: a clinicopathologic study of 70 cases". The American journal of surgical pathology. 21 (8): 871–883. PMID 9255250. Unknown parameter
|month=
ignored (help) - ↑ M. M. Lieber, K. M. Tomera & G. M. Farrow (1981). "Renal oncocytoma". The Journal of urology. 125 (4): 481–485. PMID 7218443. Unknown parameter
|month=
ignored (help) - ↑ 5.0 5.1 Neisius, D.; Braedel, H. U.; Schindler, E.; Hoene, E.; Alloussi, Sch. (1988). "Computed tomographic and angiographic findings in renal oncocytoma". The British Journal of Radiology. 61 (731): 1019–1025. doi:10.1259/0007-1285-61-731-1019. ISSN 0007-1285.
- ↑ M. R. Licht, A. C. Novick, R. R. Tubbs, E. A. Klein, H. S. Levin & S. B. Streem (1993). "Renal oncocytoma: clinical and biological correlates". The Journal of urology. 150 (5 Pt 1): 1380–1383. PMID 8411404. Unknown parameter
|month=
ignored (help) - ↑ F. Bertoni, C. Ferri, P. Bacchini, G. Corrado, A. Benati, D. Mannini & F. Corrado (1989). "Oncocytoma and low-grade oncocytic carcinoma of the kidney". European urology. 16 (2): 101–109. PMID 2714326.
- ↑ C. B. Dechet, D. G. Bostwick, M. L. Blute, S. C. Bryant & H. Zincke (1999). "Renal oncocytoma: multifocality, bilateralism, metachronous tumor development and coexistent renal cell carcinoma". The Journal of urology. 162 (1): 40–42. doi:10.1097/00005392-199907000-00010. PMID 10379735. Unknown parameter
|month=
ignored (help) - ↑ H. Choi, U. A. Almagro, J. T. McManus, D. H. Norback & S. C. Jacobs (1983). "Renal oncocytoma. A clinicopathologic study". Cancer. 51 (10): 1887–1896. PMID 6831354. Unknown parameter
|month=
ignored (help) - ↑ M. B. Amin, T. B. Crotty, S. K. Tickoo & G. M. Farrow (1997). "Renal oncocytoma: a reappraisal of morphologic features with clinicopathologic findings in 80 cases". The American journal of surgical pathology. 21 (1): 1–12. PMID 8990136. Unknown parameter
|month=
ignored (help) - ↑ B. Perez-Ordonez, G. Hamed, S. Campbell, R. A. Erlandson, P. Russo, P. B. Gaudin & V. E. Reuter (1997). "Renal oncocytoma: a clinicopathologic study of 70 cases". The American journal of surgical pathology. 21 (8): 871–883. PMID 9255250. Unknown parameter
|month=
ignored (help) - ↑ M. M. Lieber, K. M. Tomera & G. M. Farrow (1981). "Renal oncocytoma". The Journal of urology. 125 (4): 481–485. PMID 7218443. Unknown parameter
|month=
ignored (help) - ↑ M. R. Licht, A. C. Novick, R. R. Tubbs, E. A. Klein, H. S. Levin & S. B. Streem (1993). "Renal oncocytoma: clinical and biological correlates". The Journal of urology. 150 (5 Pt 1): 1380–1383. PMID 8411404. Unknown parameter
|month=
ignored (help) - ↑ F. Bertoni, C. Ferri, P. Bacchini, G. Corrado, A. Benati, D. Mannini & F. Corrado (1989). "Oncocytoma and low-grade oncocytic carcinoma of the kidney". European urology. 16 (2): 101–109. PMID 2714326.
- ↑ C. B. Dechet, D. G. Bostwick, M. L. Blute, S. C. Bryant & H. Zincke (1999). "Renal oncocytoma: multifocality, bilateralism, metachronous tumor development and coexistent renal cell carcinoma". The Journal of urology. 162 (1): 40–42. doi:10.1097/00005392-199907000-00010. PMID 10379735. Unknown parameter
|month=
ignored (help)