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! style="background: #696969; color: #FFFFFF; text-align: center;" |Major
! style="background: #696969; color: #FFFFFF; text-align: center;" |Major
| style="background: #DCDCDC; padding: 5px; text-align: left;" |
| style="background: #DCDCDC; padding: 5px; text-align: left;" |Typical attacks (1-4)
 
1- Generalised peritonitis
 
2- Unilateral pleuritis or pericarditis
 
3- Monoarthritis (hip, knee, ankle)
 
4- Fever alone
 
5- Incomplete abdominal attack


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! style="background: #696969; color: #FFFFFF; text-align: center;" |Minor
! style="background: #696969; color: #FFFFFF; text-align: center;" |Minor
| style="background: #DCDCDC; padding: 5px; text-align: left;" |
| style="background: #DCDCDC; padding: 5px; text-align: left;" |Incomplete attacks involving either or both
 
of the following sites
 
1- Chest
 
2- Joint
 
3- Exertional leg pain
 
4- Favorable response to colchicine
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===Tel Hashomer criteria===
===Tel Hashomer criteria===

Revision as of 19:06, 22 May 2019

Familial Mediterranean Fever Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Familial Mediterranean Fever from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic study of choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X ray

Echocardiography and Ultrasound

CT scan

MRI

Other imaging Studies

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary prevention

Secondary prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Diagnostic Study of Choice

Study of choice

Familial Mediterranean fever is primarily diagnosed based on the clinical presentation.

The comparison of various diagnostic studies for familial Mediterranean fever

Test Sensitivity Specificity
Tel Hashomer criteria ...% ...%
Livneh criteria ...% ...%

[Name of test with higher sensitivity and specificity] is the preferred investigation based on the sensitivity and specificity

The Tel Hashomer for diagnosing familial Mediterranean fever

Type Criteria
Major I. Recurrent episodes of fever plus serositis

II. AA type of amyloidosis without predisposing disease

III. Response to colchicine

Minor I. Recurrent febrile attacks

II. Erysipelas-like erythema

III. Family history in first-degree relatives

The Livneh criteria for diagnosing familial Mediterranean fever

Type Criteria
Major Typical attacks (1-4)

1- Generalised peritonitis

2- Unilateral pleuritis or pericarditis

3- Monoarthritis (hip, knee, ankle)

4- Fever alone

5- Incomplete abdominal attack

Minor Incomplete attacks involving either or both

of the following sites

1- Chest

2- Joint

3- Exertional leg pain

4- Favorable response to colchicine

Tel Hashomer criteria

[Disease name] may be diagnosed at any time if one or more of the following criteria are met:

  • Criteria 1
  • Criteria 2
  • Criteria 3

The diagnosis of Familial Mediterranean fever is made when at least 2 of the following diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4].

References