Familial mediterranean fever laboratory Findings: Difference between revisions
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==Overview== | ==Overview== | ||
An [[acute phase response]] is present during attacks, with high [[C-reactive protein]] levels, an elevated [[white blood cell]] count and other markers of [[inflammation]]. | An [[acute phase response]] is present during attacks, with high [[C-reactive protein]] levels, an elevated [[white blood cell]] count and other markers of [[inflammation]]. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
There are no [[diagnostic]] [[laboratory]] findings associated with [[Familial mediterranean fever|familial Mediterranean fever]]. However, this [[disorder]] is associated with an increase in [[acute phase reactant]] such as:<ref name="pmid11779767">{{cite journal |vauthors=Korkmaz C, Ozdogan H, Kasapçopur O, Yazici H |title=Acute phase response in familial Mediterranean fever |journal=Ann. Rheum. Dis. |volume=61 |issue=1 |pages=79–81 |date=January 2002 |pmid=11779767 |pmc=1753891 |doi=10.1136/ard.61.1.79 |url=}}</ref> | There are no [[diagnostic]] [[laboratory]] findings associated with [[Familial mediterranean fever|familial Mediterranean fever]]. However, this [[disorder]] is associated with an increase in [[acute phase reactant]] such as:<ref name="pmid11779767">{{cite journal |vauthors=Korkmaz C, Ozdogan H, Kasapçopur O, Yazici H |title=Acute phase response in familial Mediterranean fever |journal=Ann. Rheum. Dis. |volume=61 |issue=1 |pages=79–81 |date=January 2002 |pmid=11779767 |pmc=1753891 |doi=10.1136/ard.61.1.79 |url=}}</ref> | ||
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*[[Serum amyloid A]] ([[Serum amyloid A protein|SAA]]) | *[[Serum amyloid A]] ([[Serum amyloid A protein|SAA]]) | ||
Urinary sediment of [[patients]] with [[FMF]] may show [[hematuria]].<ref name="KallinichAktay2015">{{cite journal|last1=Kallinich|first1=Tilmann|last2=Aktay|first2=Nuray|last3=Ozen|first3=Seza|title=Special Aspects of Familial Mediterranean Fever in Childhood|volume=3|year=2015|pages=31–45|issn=2282-6505|doi=10.1007/978-3-319-14615-7_3}}</ref> | Urinary sediment of [[patients]] with [[FMF]] may show [[hematuria]].<ref name="KallinichAktay2015">{{cite journal|last1=Kallinich|first1=Tilmann|last2=Aktay|first2=Nuray|last3=Ozen|first3=Seza|title=Special Aspects of Familial Mediterranean Fever in Childhood|volume=3|year=2015|pages=31–45|issn=2282-6505|doi=10.1007/978-3-319-14615-7_3}}</ref> | ||
*In patients with a long history of attacks, monitoring the [[renal function]] is of importance in predicting [[chronic renal failure]].<ref name="Livneh">Livneh A, Langevitz P. Diagnostic and treatment concerns in familial Mediterranean fever. ''Baillieres Best Pract Res Clin Rheumatol'' 2000;14(3):477-98. PMID 10985982.</ref> | |||
==References== | ==References== | ||
Revision as of 02:43, 5 June 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
An acute phase response is present during attacks, with high C-reactive protein levels, an elevated white blood cell count and other markers of inflammation.
Laboratory Findings
There are no diagnostic laboratory findings associated with familial Mediterranean fever. However, this disorder is associated with an increase in acute phase reactant such as:[1]
Urinary sediment of patients with FMF may show hematuria.[2]
- In patients with a long history of attacks, monitoring the renal function is of importance in predicting chronic renal failure.[3]
References
- ↑ Korkmaz C, Ozdogan H, Kasapçopur O, Yazici H (January 2002). "Acute phase response in familial Mediterranean fever". Ann. Rheum. Dis. 61 (1): 79–81. doi:10.1136/ard.61.1.79. PMC 1753891. PMID 11779767.
- ↑ Kallinich, Tilmann; Aktay, Nuray; Ozen, Seza (2015). "Special Aspects of Familial Mediterranean Fever in Childhood". 3: 31–45. doi:10.1007/978-3-319-14615-7_3. ISSN 2282-6505.
- ↑ Livneh A, Langevitz P. Diagnostic and treatment concerns in familial Mediterranean fever. Baillieres Best Pract Res Clin Rheumatol 2000;14(3):477-98. PMID 10985982.