Meningioma classification: Difference between revisions
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*Meningothelial, fibrous, [[transitional]], psammomatous,<br> angiomatous, micrcystic, secretory, lymphoplasmacyte-rich, and metaplastic meningioma | *Meningothelial, fibrous, [[transitional]], psammomatous,<br> angiomatous, micrcystic, secretory, lymphoplasmacyte-rich, and metaplastic meningioma | ||
*They are low-grade tumors that grow very slowly and rarely invade the surrounding [[tissues]] | *They are low-grade [[Tumor|tumors]] that grow very slowly and rarely invade the surrounding [[tissues]] | ||
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*Chordoid, clear cell, and atypical meningioma. | *Chordoid, clear cell, and atypical meningioma. | ||
*These are not clearly [[malignant]], but grow faster than benign meningiomas | *These are not clearly [[malignant]], but grow faster than [[benign]] meningiomas | ||
*4 or more mitotic cells per hpf and/or 3 or more of the following features: small cells, increased cellularity, necrosis, prominent nucleoli, sheeting, &/or brain invasion in an otherwise Grade I tumor | *4 or more mitotic cells per hpf and/or 3 or more of the following features: small cells, increased cellularity, [[necrosis]], prominent [[nucleoli]], sheeting, &/or brain invasion in an otherwise Grade I [[tumor]] | ||
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*Rhabdoid, papillary, and anaplastic meningioma | *Rhabdoid, papillary, and anaplastic meningioma | ||
*20 or more mitoses per 10 hpf and/or possess cytological characteristics of an obvious malignancy such that the tumor cell resembles carcinoma, sarcoma, or melanoma. | *20 or more mitoses per 10 hpf and/or possess cytological characteristics of an obvious [[malignancy]] such that the [[tumor]] cell resembles [[carcinoma]], [[sarcoma]], or [[melanoma]]. | ||
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Revision as of 18:22, 11 June 2019
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Meningioma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Meningioma classification On the Web |
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American Roentgen Ray Society Images of Meningioma classification |
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Risk calculators and risk factors for Meningioma classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Meningioma has been classified into 3 groups by the WHO: benign classic meningioma (WHO grade 1), atypical meningioma (WHO grade 2), and anaplastic malignant meningioma (WHO grade 3). The WHO grade 1 group grow very slowly and consists of about 9 variants. About 3 variants correspond to WHO grade II, their association with malignancy isn't clear but they grow faster than benign meningiomas. About 2 variants correspond to WHO grade III.
Classification
- WHO has classified meningiomas into histo- and cytomorphological variants. Nine variants correspond to WHO grade I which are the benign classic meningiomas, three correspond to WHO grade II which are atypical meningiomas, and two in WHO grade III and are anaplastic malignant meningiomas.[1]
| WHO grade | Subtypes |
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Benign classic meningioma |
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Atypical meningioma |
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Anaplastic malignant meningioma |
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References
- ↑ 1.0 1.1 Harter, Patrick N.; Braun, Yannick; Plate, Karl H. (2017). "Classification of meningiomas—advances and controversies". Chinese Clinical Oncology. 6 (S1): S2–S2. doi:10.21037/cco.2017.05.02. ISSN 2304-3865.
- ↑ Commins, Deborah L.; Atkinson, Roscoe D.; Burnett, Margaret E. (2007). "Review of meningioma histopathology". Neurosurgical Focus. 23 (4): E3. doi:10.3171/FOC-07/10/E3. ISSN 1092-0684.