Cryopyrin-associated periodic syndrome history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
The cryopyrin-associated periodic syndrome is a spectrum of three different clinical phenotypes with the mildest form being familial cold autoinflammatory syndrome (FCAS), formerly called familial cold urticaria and neonatal-onset multisystem inflammatory disorder (NOMID), also known as chronic infantile neurologic cutaneous and articular (CINCA) as the most severe form. | |||
Muckle-Wells syndrome (MWS) is the intermediate form of the disease in terms of severity. Symptoms of the cryopyrin-associated periodic syndrome include episodes of cold-induced fever, skin rash, and joint pain. | |||
==History and Symptoms== | ==History and Symptoms== | ||
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**Headache | **Headache | ||
*Less common symptoms of Muckle-Wells syndrome (MWS) include: | *Less common symptoms of Muckle-Wells syndrome (MWS) include: | ||
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*Less common symptoms of Neonatal-onset multisystem inflammatory disorder (NOMID) include: | *Less common symptoms of Neonatal-onset multisystem inflammatory disorder (NOMID) include: | ||
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==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 20:08, 2 July 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
The cryopyrin-associated periodic syndrome is a spectrum of three different clinical phenotypes with the mildest form being familial cold autoinflammatory syndrome (FCAS), formerly called familial cold urticaria and neonatal-onset multisystem inflammatory disorder (NOMID), also known as chronic infantile neurologic cutaneous and articular (CINCA) as the most severe form. Muckle-Wells syndrome (MWS) is the intermediate form of the disease in terms of severity. Symptoms of the cryopyrin-associated periodic syndrome include episodes of cold-induced fever, skin rash, and joint pain.
History and Symptoms
- Symptoms of the cryopyrin-associated periodic syndrome include episodes of cold-induced fever, skin rash, and joint pain.
Common Symptoms
- Common symptoms of the familial cold autoinflammatory syndrome (FCAS) include:
- Cold-induced episodes of fever
- Joint pain
- Skin rash
- Erythema of the eye
- Common symptoms of Muckle-Wells syndrome (MWS) include:
- Episodes of fever
- Joint pain
- Headache
- Progressive hearing loss
- Common symptoms of Neonatal-onset multisystem inflammatory disorder (NOMID) include:
- Urticarial skin rash
- Hearing loss
- Limb, and joint pain
Less Common Symptoms
- Less common symptoms of the familial cold autoinflammatory syndrome (FCAS) include:
- Fatigue
- Headache
- Less common symptoms of Muckle-Wells syndrome (MWS) include:
- Less common symptoms of Neonatal-onset multisystem inflammatory disorder (NOMID) include: