Palmar plantar erythrodysesthesia classification: Difference between revisions
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==Overview== | ==Overview== | ||
A number of different classifications have been used for grading the severity of | A number of different [[Classification|classifications]] have been used for grading the severity of palmar plantar erythrodysesthesia (PPE). The [[Classification|classifications]] suggested by the [[National Cancer Institute|National Cancer Institute (NCI)]], and the [[World Health Organization|World Health Organization (WHO)]] are the two most commonly used. | ||
==Classification== | ==Classification== | ||
* Palmar plantar erythrodysesthesia may be classified into 3 grades according to the National Cancer Institute (NCI).<ref name="urlProtocol Development | CTEP">{{cite web |url=https://ctep.cancer.gov/protocolDevelopment/electronic_applications/ctc.htm |title=Protocol Development | CTEP |format= |work= |accessdate=}}</ref> | * Palmar plantar erythrodysesthesia (PPE) may be [[Classif|classified]] into 3 grades according to the [[National Cancer Institute|National Cancer Institute (NCI)]].<ref name="urlProtocol Development | CTEP">{{cite web |url=https://ctep.cancer.gov/protocolDevelopment/electronic_applications/ctc.htm |title=Protocol Development | CTEP |format= |work= |accessdate=}}</ref> | ||
{| class="wikitable" | {| class="wikitable" | ||
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! | ! | ||
|- | |- | ||
!1 | |||
|Minimal skin changes (e.g, erythema, edema, or hyperkeratosis) without pain | | | ||
* Minimal [[skin changes]] (e.g, [[erythema]], [[edema]], or [[hyperkeratosis]]) without [[pain]] | |||
|- | |- | ||
!2 | |||
|Skin changes (e.g, peeling, blisters, bleeding, fissures, edema, or hyperkeratosis) with pain; limiting instrumental ADL | | | ||
* [[Skin changes]] (e.g, peeling, [[Blister|blisters]], [[bleeding]], [[Fissure|fissures]], [[edema]], or [[hyperkeratosis]]) with [[pain]]; limiting instrumental [[Activities of daily living|ADL]] | |||
|- | |- | ||
!3 | |||
|Severe skin changes (e.g, peeling, blisters, bleeding, fissures, edema, or hyperkeratosis) with pain; limiting self care ADL | | | ||
* Severe [[skin changes]] (e.g, peeling, [[Blister|blisters]], [[bleeding]], [[Fissure|fissures]], [[edema]], or [[hyperkeratosis]]) with [[pain]]; limiting self care [[Activities of daily living|ADL]] | |||
|}<br /> | |}<br /> | ||
*Palmar plantar erythrodysesthesis may be classified into 4 grades based on the World Health Organization. <ref name="pmid11702367">{{cite journal| author=Nagore E, Insa A, Sanmartín O| title=Antineoplastic therapy-induced palmar plantar erythrodysesthesia ('hand-foot') syndrome. Incidence, recognition and management. | journal=Am J Clin Dermatol | year= 2000 | volume= 1 | issue= 4 | pages= 225-34 | pmid=11702367 | doi=10.2165/00128071-200001040-00004 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11702367 }} </ref> | *Palmar plantar erythrodysesthesis (PPE) may be [[Classification|classified]] into 4 grades based on the [[World Health Organization|World Health Organization (WHO)]]. <ref name="pmid11702367">{{cite journal| author=Nagore E, Insa A, Sanmartín O| title=Antineoplastic therapy-induced palmar plantar erythrodysesthesia ('hand-foot') syndrome. Incidence, recognition and management. | journal=Am J Clin Dermatol | year= 2000 | volume= 1 | issue= 4 | pages= 225-34 | pmid=11702367 | doi=10.2165/00128071-200001040-00004 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11702367 }} </ref> | ||
{| class="wikitable" | {| class="wikitable" | ||
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! | ! | ||
|- | |- | ||
!1 | |||
|Dysesthesia/paresthesia, tingling in the hands and feet | | | ||
* [[Dysesthesia]]/[[paresthesia]], [[tingling]] in the [[Hand|hands]] and [[feet]] | |||
|- | |- | ||
!2 | |||
|Discomfort in holding objects and upon walking, painless swelling or erythema | | | ||
* [[Discomfort]] in holding objects and upon walking, painless [[Edema|swelling]] or [[erythema]] | |||
|- | |- | ||
| | !3 | ||
|Painful erythema and swelling of palms and soles, periungual erythema and swelling | | | ||
* [[Pain|Painful]] [[erythema]] and [[Edema|swelling]] of [[Palms of the hands|palms]] and [[Sole (foot)|soles]], periungual [[erythema]] and [[Edema|swelling]] | |||
|- | |- | ||
!4 | |||
|Desquamation, ulceration, blistering, severe pain | | | ||
* [[Desquamation]], [[Ulcer|ulceration]], [[Blister|blistering]], severe [[pain]] | |||
|} | |} | ||
Latest revision as of 18:58, 4 July 2019
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Palmar plantar erythrodysesthesia Microchapters |
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Differentiating Palmar plantar erythrodysesthesia from other Diseases |
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Diagnosis |
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Treatment |
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Palmar plantar erythrodysesthesia classification On the Web |
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American Roentgen Ray Society Images of Palmar plantar erythrodysesthesia classification |
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Palmar plantar erythrodysesthesia classification in the news |
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Directions to Hospitals Treating Palmar plantar erythrodysesthesia |
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Risk calculators and risk factors for Palmar plantar erythrodysesthesia classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mandana Chitsazan, M.D. [2]
Overview
A number of different classifications have been used for grading the severity of palmar plantar erythrodysesthesia (PPE). The classifications suggested by the National Cancer Institute (NCI), and the World Health Organization (WHO) are the two most commonly used.
Classification
- Palmar plantar erythrodysesthesia (PPE) may be classified into 3 grades according to the National Cancer Institute (NCI).[1]
| GRADES | |
|---|---|
| 1 |
|
| 2 |
|
| 3 |
|
- Palmar plantar erythrodysesthesis (PPE) may be classified into 4 grades based on the World Health Organization (WHO). [2]
| GRADES | |
|---|---|
| 1 |
|
| 2 |
|
| 3 | |
| 4 |
|
Gallery
 Grades 1–3, according to the National Cancer Institute Common Terminology Criteria for Adverse events, version 4. Images shown above are courtesy of Siegfried Segaert and Eric Van Cutsem |
References
- ↑ "Protocol Development | CTEP".
- ↑ Nagore E, Insa A, Sanmartín O (2000). "Antineoplastic therapy-induced palmar plantar erythrodysesthesia ('hand-foot') syndrome. Incidence, recognition and management". Am J Clin Dermatol. 1 (4): 225–34. doi:10.2165/00128071-200001040-00004. PMID 11702367.