Cryopyrin-associated periodic syndrome diagnostic study of choice: Difference between revisions
Jump to navigation
Jump to search
Created page with "__NOTOC__ {{Cryopyrin-associated periodic syndrome}} {{CMG}}; {{AE}} {{Sahar}} == Overview == Cryopyrin-associated periodic syndrome is primarily diagnosed base..." |
No edit summary |
||
| Line 33: | Line 33: | ||
! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF|Presence}} !! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF|Score}} | ! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF|Presence}} !! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF|Score}} | ||
|- | |- | ||
! style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" | | ! style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" |Urticarial rash | ||
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | | | style="padding: 5px 5px; background: #F5F5F5;" align="center" |25 | ||
|- | |- | ||
! style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" | | ! style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" |Neurosensorial hearing loss | ||
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | | | style="padding: 5px 5px; background: #F5F5F5;" align="center" |25 | ||
|- | |- | ||
! style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" | | ! style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" |Conjunctivitis | ||
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | | | style="padding: 5px 5px; background: #F5F5F5;" align="center" |10 | ||
|- | |- | ||
! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF|Absence}} !! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF|Score}} | ! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF|Absence}} !! style="background: #4479BA; width: 150px;" | {{fontcolor|#FFF|Score}} | ||
|- | |- | ||
! style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" | | ! style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" |Exudative pharyngitis | ||
| style="padding: 5px 5px; background: #F5F5F5;" align="center" | | | style="padding: 5px 5px; background: #F5F5F5;" align="center" |25 | ||
|- | |- | ||
! style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" | | ! style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" |Abdominal pain | ||
| style="padding: 5px 5px; background: #F5F5F5;" align="center" |15 | | style="padding: 5px 5px; background: #F5F5F5;" align="center" |15 | ||
|} | |} | ||
Revision as of 14:52, 8 July 2019
|
Cryopyrin-associated periodic syndrome Microchapters |
|
Differentiating Cryopyrin-associated periodic syndrome from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Cryopyrin-associated periodic syndrome diagnostic study of choice On the Web |
|
American Roentgen Ray Society Images of Cryopyrin-associated periodic syndrome diagnostic study of choice |
|
FDA on Cryopyrin-associated periodic syndrome diagnostic study of choice |
|
CDC on Cryopyrin-associated periodic syndrome diagnostic study of choice |
|
Cryopyrin-associated periodic syndrome diagnostic study of choice in the news |
|
Blogs on Cryopyrin-associated periodic syndrome diagnostic study of choice |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
Cryopyrin-associated periodic syndrome is primarily diagnosed based on the clinical presentation.
Diagnostic Study of Choice
Study of choice
- Genetic analysis is the gold standard test for the diagnosis of the cryopyrin-associated periodic syndrome.
- However, the first step to diagnose this condition is the clinical features.
The comparison of various diagnostic studies for [disease name]
| Test | Sensitivity | Specificity |
|---|---|---|
| Test 1 | ...% | ...% |
| Test 2 | ...% | ...% |
[Name of test with higher sensitivity and specificity] is the preferred investigation based on the sensitivity and specificity
Euro fever criteria
- Cryopyrin-associated periodic syndrome is primarily diagnosed based on clinical presentation.
- In 2014, Eurofever registry developed a set of criteria for the diagnosis of the four major periodic fever syndromes. Table below is the diagnostic criteria for CAPS.[1]
| Presence | Score |
|---|---|
| Urticarial rash | 25 |
| Neurosensorial hearing loss | 25 |
| Conjunctivitis | 10 |
| Absence | Score |
| Exudative pharyngitis | 25 |
| Abdominal pain | 15 |
- The cut-off value for the diagnosis of CAPS is score equal or higher than 52 scores.
- The overall sensitivity and specificity of this set of criteria for the diagnosis of this disorder is 70% and 95%, respectively.
References
- ↑ Federici, Silvia; Sormani, Maria Pia; Ozen, Seza; Lachmann, Helen J; Amaryan, Gayane; Woo, Patricia; Koné-Paut, Isabelle; Dewarrat, Natacha; Cantarini, Luca; Insalaco, Antonella; Uziel, Yosef; Rigante, Donato; Quartier, Pierre; Demirkaya, Erkan; Herlin, Troels; Meini, Antonella; Fabio, Giovanna; Kallinich, Tilmann; Martino, Silvana; Butbul, Aviel Yonatan; Olivieri, Alma; Kuemmerle-Deschner, Jasmin; Neven, Benedicte; Simon, Anna; Ozdogan, Huri; Touitou, Isabelle; Frenkel, Joost; Hofer, Michael; Martini, Alberto; Ruperto, Nicolino; Gattorno, Marco (2015). "Evidence-based provisional clinical classification criteria for autoinflammatory periodic fevers". Annals of the Rheumatic Diseases. 74 (5): 799–805. doi:10.1136/annrheumdis-2014-206580. ISSN 0003-4967.