Hepatopulmonary syndrome differential diagnosis: Difference between revisions
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! style="background: #4479BA; color: #FFFFFF; text-align: center;|Contrast enhanced echocardiography | ! style="background: #4479BA; color: #FFFFFF; text-align: center;|Contrast enhanced echocardiography | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" | | | style="background: #DCDCDC; padding: 5px; text-align: center;" |HSP | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" | | | style="background: #DCDCDC; padding: 5px; text-align: center;" |PPH | ||
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| style="background: #DCDCDC; padding: 5px; text-align: center;" | | | style="background: #DCDCDC; padding: 5px; text-align: center;" |HHT | ||
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* '''Chronic liver disease signs''' including, spider angioma, red palms, edema, gynecomastia | * '''Chronic liver disease signs''' including, spider angioma, red palms, edema, gynecomastia | ||
* '''Respiratory symptoms''' including, shortness of breath, clubbed fingers, and cyanosis. | * '''Respiratory symptoms''' including, shortness of breath, clubbed fingers, and cyanosis. | ||
*Hepatopulmonary syndrome ('''HPS''') must be differentiated from portopulmonary hypertension ('''PPH''') and hereditary hemorrhagic telangiectasia '''(HHT'''). | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category: (name of the system)]] | [[Category: (name of the system)]] | ||
Revision as of 16:55, 8 July 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]
Overview
Hepatopulmonary syndrome (HPS) must be differentiated from portopulmonary hypertension (PPH) and hereditary hemorrhagic telangiectasia (HHT).
Differentiating Hepatopulmonary Syndrome from other Diseases
Hepatopulmonary syndrome (HPS) must be differentiated from portopulmonary hypertension (PPH) and hereditary hemorrhagic telangiectasia (HHT).
Differentiating hepatopulmonary syndrome from other diseases on the basis of pulse oximetry, arterial blood gas (ABG) analysis , contrast enhanced echocardiography; 99mTc scan: lung perfusion scintigraphy with technetium 99mTc labeled macro aggregated albumin, chest CT scan , pulmonary angiography, and pulmonary function test.
On the basis pulse oximetry, arterial blood gas (ABG) analysis , contrast enhanced echocardiography; 99mTc scan: lung perfusion scintigraphy with technetium 99mTc labeled macro aggregated albumin, chest CT scan , pulmonary angiography, and pulmonary function test, hepatopulmonary syndrome (HPS) must be differentiated from portopulmonary hypertension (PPH) and hereditary hemorrhagic telangiectasia (HHT).[1]
| Diseases | Clinical manifestations | Para-clinical findings | Gold standard | Additional findings | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Symptoms | Physical examination | |||||||||||||
| Lab Findings | Imaging | Histopathology | ||||||||||||
| Respiratory symptoms | Chronic liver disease symptoms | Platypnea | Orthodeoxia | Chronic liver disease signs | Pulse oximetry | Arterial blood gas (ABG) analysis | Pulmonary function test | Chest CT scan/Pulmonary angiography | 99mTc scan | Contrast enhanced echocardiography | ||||
| HSP | ||||||||||||||
| PPH | ||||||||||||||
| HHT | ||||||||||||||
| Diseases | Lab 1 | Lab 2 | Lab 3 | Imaging 1 | Imaging 2 | Imaging 3 | Histopathology | Gold standard | Additional findings | |||||
| Differential Diagnosis 4 | ||||||||||||||
| Differential Diagnosis 5 | ||||||||||||||
| Differential Diagnosis 6 | ||||||||||||||
- Platypnea (increased shortness of breath when the body is in a vertical position) and orthodeoxia (3-10 mmHg reduction in РаО2 in capillary blood during transition from horizontal to vertical position)
- 99mTc scan: lung perfusion scintigraphy with technetium 99mTc labeled macro aggregated albumin
- Chronic liver disease symptoms including, Itching, easy bruising, abdominal fullness, decreased libido, abdominal distension, and fatigue.
- Chronic liver disease signs including, spider angioma, red palms, edema, gynecomastia
- Respiratory symptoms including, shortness of breath, clubbed fingers, and cyanosis.
- Hepatopulmonary syndrome (HPS) must be differentiated from portopulmonary hypertension (PPH) and hereditary hemorrhagic telangiectasia (HHT).
References
- ↑ Krynytska I, Marushchak M, Mikolenko A, Bob A, Smachylo I, Radetska L et al. (2017) Differential diagnosis of hepatopulmonary syndrome (HPS): Portopulmonary hypertension (PPH) and hereditary hemorrhagic telangiectasia (HHT). Bosn J Basic Med Sci 17 (4):276-285. DOI:10.17305/bjbms.2017.2020 PMID: 28759737