Progeria epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare hereditary disease. The [[incidence]] of [[Hutchinson-Gilford progeria syndrome]] ([[HGPS]]) is very rare. The usual age of diagnosis for [[Hutchinson-Gilford progeria syndrome]] ([[HGPS]]) ia around two to three years of age. | Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare hereditary disease. The [[incidence]] of [[Hutchinson-Gilford progeria syndrome]] ([[HGPS]]) is very rare. The usual age of diagnosis for [[Hutchinson-Gilford progeria syndrome]] ([[HGPS]]) ia around two to three years of age. Approximately 100 cases of [[Hutchinson-Gilford progeria syndrome]] (HGPS) have been reported in the literature till now worldwide. | ||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare hereditary disease. The incidence of Hutchinson-Gilford progeria syndrome (HGPS) is very rare. The usual age of diagnosis for Hutchinson-Gilford progeria syndrome (HGPS) ia around two to three years of age. Approximately 100 cases of Hutchinson-Gilford progeria syndrome (HGPS) have been reported in the literature till now worldwide.
Epidemiology and Demographics
Incidence
- The incidence of Hutchinson-Gilford progeria syndrome (HGPS) is approximately one in four to eight million births worldwide.[1]
- The incidence of Hutchinson-Gilford progeria syndrome (HGPS) in Netherlands is 1:4,000,000.[2]
Prevalence
- The prevalence of Hutchinson-Gilford progeria syndrome (HGPS) is approximately 1 in 20 million individuals worldwide.
Age
- Hutchinson-Gilford progeria syndrome (HGPS) commonly affects individuals of very younger age rather than older age.
- The median age at diagnosis is 2.9 years overall.[3]
Race
- There is no race predilection of Hutchinson-Gilford progeria syndrome (HGPS) till now.
Gender
- Hutchinson-Gilford progeria syndrome (HGPS) affects men and women equally but males are little more commonly affected by Hutchinson-Gilford progeria syndrome (HGPS) than females.
- The male to female ratio is approximately 1.2:1.[4]
References
- ↑ Hennekam RC (2006). "Hutchinson-Gilford progeria syndrome: review of the phenotype". Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.
- ↑ Hennekam RC (2006). "Hutchinson-Gilford progeria syndrome: review of the phenotype". Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.
- ↑ Hennekam RC (2006). "Hutchinson-Gilford progeria syndrome: review of the phenotype". Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.
- ↑ Hennekam RC (2006). "Hutchinson-Gilford progeria syndrome: review of the phenotype". Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.