Progeria epidemiology and demographics: Difference between revisions
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===Race=== | ===Race=== | ||
* | * [[Hutchinson-Gilford progeria syndrome]] (HGPS) usually affects individuals of the white race. | ||
===Gender=== | ===Gender=== | ||
*[[Hutchinson-Gilford progeria syndrome]] ([[HGPS]]) affects men and women equally but males are little more commonly affected by [[Hutchinson-Gilford progeria syndrome]] | *[[Hutchinson-Gilford progeria syndrome]] ([[HGPS]]) affects men and women equally but males are little more commonly affected by [[Hutchinson-Gilford progeria syndrome]] than females. | ||
*The male to female ratio is approximately 1. | *The male to female ratio is approximately 1.5:1.<ref name="pmid168383303">{{cite journal| author=Hennekam RC| title=Hutchinson-Gilford progeria syndrome: review of the phenotype. | journal=Am J Med Genet A | year= 2006 | volume= 140 | issue= 23 | pages= 2603-24 | pmid=16838330 | doi=10.1002/ajmg.a.31346 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16838330 }}</ref> | ||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Hutchinson-Gilford progeria syndrome (HGPS) is an extremely rare hereditary disease. The incidence of Hutchinson-Gilford progeria syndrome (HGPS) is very rare. The usual age of diagnosis for Hutchinson-Gilford progeria syndrome (HGPS) ia around two to three years of age. Approximately 100 cases of Hutchinson-Gilford progeria syndrome (HGPS) have been reported in the literature till now worldwide.
Epidemiology and Demographics
Incidence
- The incidence of Hutchinson-Gilford progeria syndrome (HGPS) is approximately one in four to eight million births worldwide.[1]
- The incidence of Hutchinson-Gilford progeria syndrome (HGPS) in Netherlands is 1:4,000,000.[2]
Prevalence
- The prevalence of Hutchinson-Gilford progeria syndrome (HGPS) is approximately 1 in 20 million individuals worldwide.
Age
- Hutchinson-Gilford progeria syndrome (HGPS) commonly affects individuals of very younger age rather than older age.
- The median age at diagnosis is 2.9 years overall.[3]
Race
- Hutchinson-Gilford progeria syndrome (HGPS) usually affects individuals of the white race.
Gender
- Hutchinson-Gilford progeria syndrome (HGPS) affects men and women equally but males are little more commonly affected by Hutchinson-Gilford progeria syndrome than females.
- The male to female ratio is approximately 1.5:1.[4]
References
- ↑ Hennekam RC (2006). "Hutchinson-Gilford progeria syndrome: review of the phenotype". Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.
- ↑ Hennekam RC (2006). "Hutchinson-Gilford progeria syndrome: review of the phenotype". Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.
- ↑ Hennekam RC (2006). "Hutchinson-Gilford progeria syndrome: review of the phenotype". Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.
- ↑ Hennekam RC (2006). "Hutchinson-Gilford progeria syndrome: review of the phenotype". Am J Med Genet A. 140 (23): 2603–24. doi:10.1002/ajmg.a.31346. PMID 16838330.