Progeria causes: Difference between revisions
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===Common Causes=== | ===Common Causes=== | ||
Common causes of Hutchinson-Gilford progeria syndrome (HGPS) may include: | Common causes of Hutchinson-Gilford progeria syndrome (HGPS) may include:<ref name="pmid28811278">{{cite journal| author=Elzeneini E, Wickström SA| title=Lipodystrophic laminopathy: Lamin A mutation relaxes chromatin architecture to impair adipogenesis. | journal=J Cell Biol | year= 2017 | volume= 216 | issue= 9 | pages= 2607-2610 | pmid=28811278 | doi=10.1083/jcb.201707090 | pmc=5584192 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28811278 }}</ref> | ||
*Mutation in ''LMNA'' gene which results in production of abnormal protein laminin A which is also called progerin | *Mutation in ''LMNA'' gene which results in production of abnormal protein laminin A which is also called progerin | ||
*LMNA gene plays a very crucial role in the following: | *LMNA gene plays a very crucial role in the following: | ||
**Membrane which surrounds the cell’s nucleus | **Membrane which surrounds the cell’s nucleus and stabilizes the nuclear membrane. | ||
*The location of the LMNA gene is on chromosome 1. | *The location of the LMNA gene is on chromosome 1. | ||
Revision as of 16:58, 19 July 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
Disease name] may be caused by [cause1], [cause2], or [cause3].
OR
Common causes of [disease] include [cause1], [cause2], and [cause3].
OR
The most common cause of [disease name] is [cause 1]. Less common causes of [disease name] include [cause 2], [cause 3], and [cause 4].
OR
The cause of [disease name] has not been identified. To review risk factors for the development of [disease name], click here.
Causes
Life-threatening Causes
- Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated. There are no life-threatening causes of disease name, however complications resulting from untreated disease name is common.
- Life-threatening causes of [symptom/manifestation] include [cause1], [cause2], and [cause3].
- [Cause] is a life-threatening cause of [disease].
Common Causes
Common causes of Hutchinson-Gilford progeria syndrome (HGPS) may include:[1]
- Mutation in LMNA gene which results in production of abnormal protein laminin A which is also called progerin
- LMNA gene plays a very crucial role in the following:
- Membrane which surrounds the cell’s nucleus and stabilizes the nuclear membrane.
- The location of the LMNA gene is on chromosome 1.
Less Common Causes
Less common causes of [disease name] include:
- [Cause1]
- [Cause2]
- [Cause3]
Genetic Causes
- Hutchinson-Gilford progeria syndrome (HGPS) is caused by a mutation in the LMNA gene.
Causes by Organ System
| Cardiovascular | No underlying causes |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | No underlying causes |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | No underlying causes |
| Gastroenterologic | No underlying causes |
| Genetic | No underlying causes |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | No underlying causes |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | No underlying causes |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Causes in Alphabetical Order
List the causes of the disease in alphabetical order:
- Cause 1
- Cause 2
- Cause 3
- Cause 4
- Cause 5
- Cause 6
- Cause 7
- Cause 8
- Cause 9
- Cause 10
References
- ↑ Elzeneini E, Wickström SA (2017). "Lipodystrophic laminopathy: Lamin A mutation relaxes chromatin architecture to impair adipogenesis". J Cell Biol. 216 (9): 2607–2610. doi:10.1083/jcb.201707090. PMC 5584192. PMID 28811278.