Progeria laboratory findings: Difference between revisions
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==Laboratory Findings== | ==Laboratory Findings== | ||
Laboratory findings consistent with the diagnosis of Hutchinson-Gilford progeria syndrome (HGPS) include: | Laboratory findings consistent with the diagnosis of Hutchinson-Gilford progeria syndrome (HGPS) include:<ref name="pmid18256394">{{cite journal| author=Merideth MA, Gordon LB, Clauss S, Sachdev V, Smith AC, Perry MB et al.| title=Phenotype and course of Hutchinson-Gilford progeria syndrome. | journal=N Engl J Med | year= 2008 | volume= 358 | issue= 6 | pages= 592-604 | pmid=18256394 | doi=10.1056/NEJMoa0706898 | pmc=2940940 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18256394 }}</ref> | ||
*Decreased serum leptin levels | *Decreased serum leptin levels | ||
*Insulin resistance | *Insulin resistance | ||
*Decreased bone density | *Decreased bone density | ||
*Elevated platelet counts | |||
*Elevated serum phosphorus levels | |||
*Some patients with Hutchinson-Gilford progeria syndrome (HGPS) may have prolonged prothrombin time | *Some patients with Hutchinson-Gilford progeria syndrome (HGPS) may have prolonged prothrombin time | ||
Revision as of 17:01, 31 July 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
OR
Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
OR
[Test] is usually normal for patients with [disease name].
OR
Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].
OR
There are no diagnostic laboratory findings associated with [disease name].
Laboratory Findings
Laboratory findings consistent with the diagnosis of Hutchinson-Gilford progeria syndrome (HGPS) include:[1]
- Decreased serum leptin levels
- Insulin resistance
- Decreased bone density
- Elevated platelet counts
- Elevated serum phosphorus levels
- Some patients with Hutchinson-Gilford progeria syndrome (HGPS) may have prolonged prothrombin time
References
- ↑ Merideth MA, Gordon LB, Clauss S, Sachdev V, Smith AC, Perry MB; et al. (2008). "Phenotype and course of Hutchinson-Gilford progeria syndrome". N Engl J Med. 358 (6): 592–604. doi:10.1056/NEJMoa0706898. PMC 2940940. PMID 18256394.