Germ cell tumor classification: Difference between revisions
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* [[Back pain]] | * [[Back pain]] | ||
* [[Abdominal discomfort]] | * [[Abdominal discomfort]] | ||
* [[Abdominal mass]]. | * [[Abdominal mass]]. | ||
| style="padding: 5px 5px; background: #F5F5F5;" |Gross: pale gray to yellow nodules that are uniform or slightly lobulated and often bulge from the cut surface | | style="padding: 5px 5px; background: #F5F5F5;" |Gross: pale gray to yellow nodules that are uniform or slightly lobulated and often bulge from the cut surface | ||
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* Complete blood count and blood chemistry tests.<ref name="Diagnosisoftesticularcancer1">Diagnosis of testicular cancer. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/testicular/diagnosis/?region=on. Accessed on March 2, 2016</ref> | |||
* Abnormal serum tumor marker levels ([[LDH]], [[HCG]]).<ref name="Diagnosisoftesticularcancer1" /><ref name="diagnosisoftesticularseminomawiki1">Diagnosis of seminoma. Wikipedia 2016. https://en.wikipedia.org/wiki/Seminoma. Accessed on March 3, 2016</ref> | |||
* CT: Metastases to the para-aortic, inguinal, or iliac lymph nodes. Visceral metastasis may also be seen. | |||
* Pelvic MRI: may be diagnostic. multinodular tumors of uniform signal intensity | |||
* Hypo- to isointense on T2-weighted images and inhomogenous enhancement on contrast enhanced T1-weighted images.<ref name="radiographicimagesofseminoma1">Radiographic features of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on March 7, 2016</ref> | |||
* Other diagnostic studies for seminoma include [[biopsy]], [[PET|FDG-PET scan]], and [[bone scan]].<ref name="pathologyofseminoma1">Microscopic pathology of seminoma. Libre pathology 2016. http://librepathology.org/wiki/Seminoma. Accessed on March 3, 2016</ref> | |||
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Revision as of 14:17, 1 August 2019
| Types | Subtypes | Signs and Symptoms | Histopathology | Lab finding | Treatment | Prognosis |
|---|---|---|---|---|---|---|
| Gonadal |
Seminoma |
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Gross: pale gray to yellow nodules that are uniform or slightly lobulated and often bulge from the cut surface |
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Dysgerminoma |
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Germinoma |
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| Extragonadal | Embryonic |
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Teratoma |
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Extraembryonic |
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Coriocarcinoma |
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Yolk sac tumor |
- ↑ 1.0 1.1 Diagnosis of testicular cancer. Canadian cancer society 2016. http://www.cancer.ca/en/cancer-information/cancer-type/testicular/diagnosis/?region=on. Accessed on March 2, 2016
- ↑ Diagnosis of seminoma. Wikipedia 2016. https://en.wikipedia.org/wiki/Seminoma. Accessed on March 3, 2016
- ↑ Radiographic features of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on March 7, 2016
- ↑ Microscopic pathology of seminoma. Libre pathology 2016. http://librepathology.org/wiki/Seminoma. Accessed on March 3, 2016