Dermatofibroma classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Homa Najafi, M.D.[2]

Overview

Dermatofibromas are classed as benign skin lesions, meaning that they are completely harmless, though they may be confused with a variety of subcutaneous tumours. Deep penetrating dermatofibromas may be difficult to distinguish, even histologically, from rare malignant fibrohistocytic tumours like dermatofibrosarcoma protuberans.

Classification

Dermatofibromas are classed as benign skin lesions, meaning that they are completely harmless, though they may be confused with a variety of subcutaneous tumours. Deep penetrating dermatofibromas may be difficult to distinguish, even histologically, from rare malignant fibrohistocytic tumours like dermatofibrosarcoma protuberans.

Overview

There is no established system for the classification of [disease name].

Dermatofibroma may be classified according to [classification method] into [number] subtypes/groups: [group1], [group2], [group3], and [group4].

[Disease name] may be classified into [large number > 6] subtypes based on [classification method 1], [classification method 2], and [classification method 3]. [Disease name] may be classified into several subtypes based on [classification method 1], [classification method 2], and [classification method 3].

Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.

If the staging system involves specific and characteristic findings and features: According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].

The staging of [malignancy name] is based on the [staging system].

There is no established system for the staging of [malignancy name].

Classification

Dermatofibroma may be classified according to histopathology into [number] subtypes/groups:

• [Group1]
• [Group2]
• [Group3]
• [Group4]

OR

[Disease name] may be classified into [large number > 6] subtypes based on:

• [Classification method 1]
• [Classification method 2]
• [Classification method 3]

[Disease name] may be classified into several subtypes based on:

• [Classification method 1]
• [Classification method 2]
• [Classification method 3]

OR

Based on the duration of symptoms, [disease name] may be classified as either acute or chronic.

OR

If the staging system involves specific and characteristic findings and features:

According to the [staging system + reference], there are [number] stages of [malignancy name] based on the [finding1], [finding2], and [finding3]. Each stage is assigned a [letter/number1] and a [letter/number2] that designate the [feature1] and [feature2].

OR

The staging of [malignancy name] is based on the [staging system].

OR

There is no established system for the staging of [malignancy name].

Histopathology varient of dermatofibroma

Variants that are prominent in architectural (low-power) properties

Variants that are prominent in cytologic or stromal (high-power) properties

Variants that have architectural (low) and cytological or stromal (high-power) properties

1.Deep penetrating dermatofibroma 2. Atrophic dermatofibroma 3. Aneurysmal fibrous histiocytoma 4. Haemangiopericytoma-like fibrous histiocytoma 5. Palisading cutaneous fibrous histiocytoma 6. Lichenoid, erosive, & ulcerated dermatofibroma 7.Plaque-like dermal fibromatosis, dermatofibroma

1. Clear cell dermatofibroma 2. Granular cell dermatofibroma 3. Myofibroblastic dermatofibroma 4. Sclerotic dermatofibroma 5. Keloidal dermatofibroma 6. Atypical/pseudosarcomatous fibrous histiocytoma, dermatofibroma with monster cells 7. Hemosiderrhotic dermatofibroma 8. Cholesterotic/lipidized dermatofibroma 9. Myxoid dermatofibroma 10. Ossifying dermatofibroma 11. Pseudolymphomatous dermatofibroma 12. Dermatofibroma with diffuse eosinophilic infiltrate

1. Epithelioid cell histiocytoma 2. Cellular benign fibrous histiocytoma 3. Smooth muscle proliferation in dermatofibroma 4. Multinucleate cell angiohistiocytoma 5. Cellular neurothekeoma 6. Combined DF