Sandbox:Sara: Difference between revisions
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{{CMG}}; {{AE}} {{S.M.}} | {{CMG}}; {{AE}} {{S.M.}} | ||
*Immunhistochemical staining of dermatofibrosarcoma protuberans shows: | |||
**Positive staining for: | |||
* | ***CD34 (strong in 95%) | ||
* | ***Vimentin | ||
** | ***Focal actin | ||
* | ***ApoD<ref name="pmid15252314">{{cite journal| author=West RB, Harvell J, Linn SC, Liu CL, Prapong W, Hernandez-Boussard T et al.| title=Apo D in soft tissue tumors: a novel marker for dermatofibrosarcoma protuberans. | journal=Am J Surg Pathol | year= 2004 | volume= 28 | issue= 8 | pages= 1063-9 | pmid=15252314 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15252314 }} </ref><ref name="pmid17885669">{{cite journal| author=Lisovsky M, Hoang MP, Dresser KA, Kapur P, Bhawan J, Mahalingam M| title=Apolipoprotein D in CD34-positive and CD34-negative cutaneous neoplasms: a useful marker in differentiating superficial acral fibromyxoma from dermatofibrosarcoma protuberans. | journal=Mod Pathol | year= 2008 | volume= 21 | issue= 1 | pages= 31-8 | pmid=17885669 | doi=10.1038/modpathol.3800971 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17885669 }} </ref><ref name="pmid20062007">{{cite journal| author=Bandarchi B, Ma L, Marginean C, Hafezi S, Zubovits J, Rasty G| title=D2-40, a novel immunohistochemical marker in differentiating dermatofibroma from dermatofibrosarcoma protuberans. | journal=Mod Pathol | year= 2010 | volume= 23 | issue= 3 | pages= 434-8 | pmid=20062007 | doi=10.1038/modpathol.2009.176 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20062007 }} </ref> | ||
** | ***bcl2 | ||
* | ***NKI-C3<ref name="pmid1553911">{{cite journal| author=Ma CK, Zarbo RJ, Gown AM| title=Immunohistochemical characterization of atypical fibroxanthoma and dermatofibrosarcoma protuberans. | journal=Am J Clin Pathol | year= 1992 | volume= 97 | issue= 4 | pages= 478-83 | pmid=1553911 | doi=10.1093/ajcp/97.4.478 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1553911 }} </ref> | ||
** | ***CD99<ref name="pmid18201229">{{cite journal| author=Diwan AH, Skelton HG, Horenstein MG, Kelly DR, Barrett TL, Bussian AH et al.| title=Dermatofibrosarcoma protuberans and giant cell fibroblastoma exhibit CD99 positivity. | journal=J Cutan Pathol | year= 2008 | volume= 35 | issue= 7 | pages= 647-50 | pmid=18201229 | doi=10.1111/j.1600-0560.2007.00872.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18201229 }} </ref> | ||
* | ***Nestin | ||
***Tenascin | |||
* | ***CD163 | ||
* | ***Factor XIIIa | ||
***CD10 | |||
* | **Negative staining for: | ||
* | ***Factor XIIIa (usually) | ||
* | ***Keratin | ||
* | ***EMA | ||
* | ***S100 | ||
** | ***HMB45 | ||
** | ***Desmin | ||
** | ***CD117<ref name="pmid17944726">{{cite journal| author=Labonte S, Hanna W, Bandarchi-Chamkhaleh B| title=A study of CD117 expression in dermatofibrosarcoma protuberans and cellular dermatofibroma. | journal=J Cutan Pathol | year= 2007 | volume= 34 | issue= 11 | pages= 857-60 | pmid=17944726 | doi=10.1111/j.1600-0560.2007.00731.x | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17944726 }} </ref> | ||
** | |||
* | |||
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Revision as of 23:14, 15 August 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]
- Immunhistochemical staining of dermatofibrosarcoma protuberans shows:
- ↑ West RB, Harvell J, Linn SC, Liu CL, Prapong W, Hernandez-Boussard T; et al. (2004). "Apo D in soft tissue tumors: a novel marker for dermatofibrosarcoma protuberans". Am J Surg Pathol. 28 (8): 1063–9. PMID 15252314.
- ↑ Lisovsky M, Hoang MP, Dresser KA, Kapur P, Bhawan J, Mahalingam M (2008). "Apolipoprotein D in CD34-positive and CD34-negative cutaneous neoplasms: a useful marker in differentiating superficial acral fibromyxoma from dermatofibrosarcoma protuberans". Mod Pathol. 21 (1): 31–8. doi:10.1038/modpathol.3800971. PMID 17885669.
- ↑ Bandarchi B, Ma L, Marginean C, Hafezi S, Zubovits J, Rasty G (2010). "D2-40, a novel immunohistochemical marker in differentiating dermatofibroma from dermatofibrosarcoma protuberans". Mod Pathol. 23 (3): 434–8. doi:10.1038/modpathol.2009.176. PMID 20062007.
- ↑ Ma CK, Zarbo RJ, Gown AM (1992). "Immunohistochemical characterization of atypical fibroxanthoma and dermatofibrosarcoma protuberans". Am J Clin Pathol. 97 (4): 478–83. doi:10.1093/ajcp/97.4.478. PMID 1553911.
- ↑ Diwan AH, Skelton HG, Horenstein MG, Kelly DR, Barrett TL, Bussian AH; et al. (2008). "Dermatofibrosarcoma protuberans and giant cell fibroblastoma exhibit CD99 positivity". J Cutan Pathol. 35 (7): 647–50. doi:10.1111/j.1600-0560.2007.00872.x. PMID 18201229.
- ↑ Labonte S, Hanna W, Bandarchi-Chamkhaleh B (2007). "A study of CD117 expression in dermatofibrosarcoma protuberans and cellular dermatofibroma". J Cutan Pathol. 34 (11): 857–60. doi:10.1111/j.1600-0560.2007.00731.x. PMID 17944726.