Sandbox:Sara: Difference between revisions

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{| class="wikitable"
{| class="wikitable"
|+Treatment options for dermatofibrosarcoma protuberans
|+Treatment options for dermatofibrosarcoma protuberans
!Treatment option
!style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Treatment option}}
!Details
!style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Details}}
|-
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|'''[[Surgery]]'''
|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |'''[[Surgery]]'''
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*[[Mohs micrographic surgery]]
*[[Mohs micrographic surgery]]
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**3-[[Dimensional analysis|dimensional]] [[histological]] evaluation of margins (necessarily recommended in order to [[Prevention (medical)|prevent]] the [[tumor]] [[Recurrence plot|recurrence]])
**3-[[Dimensional analysis|dimensional]] [[histological]] evaluation of margins (necessarily recommended in order to [[Prevention (medical)|prevent]] the [[tumor]] [[Recurrence plot|recurrence]])
|-
|-
|[[Targeted therapy|'''Targeted therapy''']]
|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |[[Targeted therapy|'''Targeted therapy''']]
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* [[Imatinib]]-[[STI571]] ([[tyrosine kinase inhibitor]]) [[therapy]] (may be [[Effective method|effective]] in [[CD117]]- [[tumors]]) is the [[Gold standard (test)|gold standard]] [[Treatments|treatment]] of [[Recurrence plot|recurrent]] or [[inoperable]] [[tumor]]
* [[Imatinib]]-[[STI571]] ([[tyrosine kinase inhibitor]]) [[therapy]] (may be [[Effective method|effective]] in [[CD117]]- [[tumors]]) is the [[Gold standard (test)|gold standard]] [[Treatments|treatment]] of [[Recurrence plot|recurrent]] or [[inoperable]] [[tumor]]
* As [[imatinib]] [[Inhibition|inhibits]] [[PDGFB]], may be [[Effective method|effective]] for [[tumors]] positive for the t(17;22) [[Translocations|translocation]]
* As [[imatinib]] [[Inhibition|inhibits]] [[PDGFB]], may be [[Effective method|effective]] for [[tumors]] positive for the t(17;22) [[Translocations|translocation]]
|-
|-
|'''[[Chemotherapy]]'''
|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |'''[[Chemotherapy]]'''
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* Less beneficial than [[targeted therapy]]
* Less beneficial than [[targeted therapy]]
|-
|-
|'''[[Radiotherapy]]'''
|style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" |'''[[Radiotherapy]]'''
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* May be required sometimes
* May be required sometimes

Revision as of 16:56, 16 August 2019


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]

Treatment options for dermatofibrosarcoma protuberans
Treatment option Details
Surgery
Targeted therapy
Chemotherapy
Radiotherapy
  • May be required sometimes

Reference

  1. Huis In 't Veld EA, van Houdt WJ (2019). "Reply to Follow-up after treatment of dermatofibrosarcoma protuberans". Cancer. doi:10.1002/cncr.32341. PMID 31251395.
  2. Loss L, Zeitouni NC (2005). "Management of scalp dermatofibrosarcoma protuberans". Dermatol Surg. 31 (11 Pt 1): 1428–33. PMID 16416612.
  3. Dawes KW, Hanke CW (1996). "Dermatofibrosarcoma protuberans treated with Mohs micrographic surgery: cure rates and surgical margins". Dermatol Surg. 22 (6): 530–4. PMID 8646467.
  4. Bowne WB, Antonescu CR, Leung DH, Katz SC, Hawkins WG, Woodruff JM; et al. (2000). "Dermatofibrosarcoma protuberans: A clinicopathologic analysis of patients treated and followed at a single institution". Cancer. 88 (12): 2711–20. PMID 10870053.
  5. DuBay D, Cimmino V, Lowe L, Johnson TM, Sondak VK (2004). "Low recurrence rate after surgery for dermatofibrosarcoma protuberans: a multidisciplinary approach from a single institution". Cancer. 100 (5): 1008–16. doi:10.1002/cncr.20051. PMID 14983497.
  6. Snow SN, Gordon EM, Larson PO, Bagheri MM, Bentz ML, Sable DB (2004). "Dermatofibrosarcoma protuberans: a report on 29 patients treated by Mohs micrographic surgery with long-term follow-up and review of the literature". Cancer. 101 (1): 28–38. doi:10.1002/cncr.20316. PMID 15221986.