Extranodal NK-T-cell lymphoma epidemiology and demographics: Difference between revisions

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=== Mortality rate ===
=== Mortality rate ===


* NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis.
* NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis.<ref name="pmid8640683">{{cite journal| author=Harabuchi Y, Imai S, Wakashima J, Hirao M, Kataura A, Osato T et al.| title=Nasal T-cell lymphoma causally associated with Epstein-Barr virus: clinicopathologic, phenotypic, and genotypic studies. | journal=Cancer | year= 1996 | volume= 77 | issue= 10 | pages= 2137-49 | pmid=8640683 | doi=10.1002/(SICI)1097-0142(19960515)77:10<2137::AID-CNCR27>3.0.CO;2-V | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8640683  }}</ref>


=== Race ===
=== Race ===


* Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.
* Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.<ref name="pmid86406832">{{cite journal| author=Harabuchi Y, Imai S, Wakashima J, Hirao M, Kataura A, Osato T et al.| title=Nasal T-cell lymphoma causally associated with Epstein-Barr virus: clinicopathologic, phenotypic, and genotypic studies. | journal=Cancer | year= 1996 | volume= 77 | issue= 10 | pages= 2137-49 | pmid=8640683 | doi=10.1002/(SICI)1097-0142(19960515)77:10<2137::AID-CNCR27>3.0.CO;2-V | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8640683  }}</ref>
* Nk cell lymphoma is usually associated with Epstein-Barr virus infection.
* Nk cell lymphoma is usually associated with Epstein-Barr virus infection.


=== Gender ===
=== Gender ===


* There is no established difference between male and female prevalence of extranodal NK cell lymphoma.  
* Extranodal NK/T-cell lymphoma shows male preponderance.<ref name="pmid27932776">{{cite journal| author=Al Shawabkeh MA, Al Sulaiti M, Al Sa'ey H, Ganesan S| title=Nasal Type Extranodal Natural Killer/T (NK/T) Cell Lymphoma Presenting as Periorbital Cellulitis: A Case Report. | journal=Am J Case Rep | year= 2016 | volume= 17 | issue=  | pages= 934-938 | pmid=27932776 | doi=10.12659/ajcr.899922 | pmc=5153321 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27932776  }}</ref>


=== Region ===
=== Region ===
Line 26: Line 26:


=== Age ===
=== Age ===
<br />
 
* The median age of onset is approximately 50 years and it is common in elderly.
* Extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensetivity or other EBV-associated disease.<ref name="pmid23341729">{{cite journal| author=Seon HS, Roh JH, Lee SH, Kang EK| title=A case of hypersensitivity to mosquito bites without peripheral natural killer cell lymphocytosis in a 6-year-old Korean boy. | journal=J Korean Med Sci | year= 2013 | volume= 28 | issue= 1 | pages= 164-6 | pmid=23341729 | doi=10.3346/jkms.2013.28.1.164 | pmc=3546098 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23341729  }}</ref>


*
*

Revision as of 14:14, 22 August 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2] Sowminya Arikapudi, M.B,B.S. [3]

Overview


Epidemiology and Demographics

Mortality rate

  • NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis.[1]

Race

  • Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.[2]
  • Nk cell lymphoma is usually associated with Epstein-Barr virus infection.

Gender

  • Extranodal NK/T-cell lymphoma shows male preponderance.[3]

Region

  • NK T cell lymphoma, nasal type (NNKTL) consist 3-10% of non-Hodgkin lymphoma in Asia and South America and less than 1% in Western countries.
  • It is estimated the incidence of NNKTL is higher in Asia by 10-folds.

Age

  • The median age of onset is approximately 50 years and it is common in elderly.
  • Extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensetivity or other EBV-associated disease.[4]

References

  1. ↑ Harabuchi Y, Imai S, Wakashima J, Hirao M, Kataura A, Osato T; et al. (1996). "Nasal T-cell lymphoma causally associated with Epstein-Barr virus: clinicopathologic, phenotypic, and genotypic studies". Cancer. 77 (10): 2137–49. doi:10.1002/(SICI)1097-0142(19960515)77:10<2137::AID-CNCR27>3.0.CO;2-V. PMID 8640683.
  2. ↑ Harabuchi Y, Imai S, Wakashima J, Hirao M, Kataura A, Osato T; et al. (1996). "Nasal T-cell lymphoma causally associated with Epstein-Barr virus: clinicopathologic, phenotypic, and genotypic studies". Cancer. 77 (10): 2137–49. doi:10.1002/(SICI)1097-0142(19960515)77:10<2137::AID-CNCR27>3.0.CO;2-V. PMID 8640683.
  3. ↑ Al Shawabkeh MA, Al Sulaiti M, Al Sa'ey H, Ganesan S (2016). "Nasal Type Extranodal Natural Killer/T (NK/T) Cell Lymphoma Presenting as Periorbital Cellulitis: A Case Report". Am J Case Rep. 17: 934–938. doi:10.12659/ajcr.899922. PMC 5153321. PMID 27932776.
  4. ↑ Seon HS, Roh JH, Lee SH, Kang EK (2013). "A case of hypersensitivity to mosquito bites without peripheral natural killer cell lymphocytosis in a 6-year-old Korean boy". J Korean Med Sci. 28 (1): 164–6. doi:10.3346/jkms.2013.28.1.164. PMC 3546098. PMID 23341729.
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